Nucleic Acids Research, 2003, Vol. 31, No. 13 3856-3858
© 2003 Oxford University Press
Building protein diagrams on the web with the residue-based diagram editor RbDe
1 Mount Sinai School of Medicine, Institute for Computational Biomedicine and Department of Physiology and Biophysics, New York, NY, USA 2 Weill Medical College of Cornell University, Physiology and Biophysics, New York, NY, USA
*To whom correspondence should be addressed. Tel: +1 212 327 7345; Fax: +1 212 327 7344; Email: fabien.campagne{at}mssm.edu
The residue-based diagram editor (RbDe) is web-based software that greatly simplifies the construction of schematic diagrams of proteins. Residue-based diagrams display the sequence of a given protein in the context of its secondary and tertiary structure. Such diagrams are frequently used to summarize mutations or sequence features, in the context of the overall topology of a protein. The initial version of RbDe was designed for transmembrane proteins and has enabled many users to create diagrams of large systems such as G protein-coupled receptors or transporters. We present an extended diagram editor that supports other families of proteins. Users can now import custom-diagram layouts, use them to render members of any protein family and generate high-quality output for publication purposes. RbDe is available free over the web, at http://icb.mssm.edu/crt/RbDe
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