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Nucleic Acids Research, 2004, Vol. 32, Database issue D332-D333
© 2004 Oxford University Press

dictyBase: a new Dictyostelium discoideum genome database

Lisa Kreppel, Petra Fey1, Pascale Gaudet1, Eric Just1, Warren A. Kibbe1, Rex L. Chisholm1 and Alan R. Kimmel*

Laboratory of Cellular and Developmental Biology (50/3351), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-8028, USA and 1 Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA

*To whom correspondence should be addressed. Tel: +1 301 496 3016; Fax: +1 310 496 5239; Email: ark1{at}helix.nih.gov

Dictyostelium discoideum is a powerful and genetically tractable model system used for the study of numerous cellular molecular mechanisms including chemotaxis, phagocytosis and signal transduction. The past 2 years have seen a significant expansion in the scope and accessibility of online resources for Dictyostelium. Recent advances have focused on the development of a new comprehensive online resource called dictyBase (http://dictybase.org). This database not only provides access to genomic data including functional annotation of genes, gene products and chromosomal mapping, but also to extensive biological information such as mutant phenotypes and corresponding reference material. In conjunction with additional sites (http://genome. imb-jena.de/dictyostelium/, http://dictyensembl. bioch.bcm.tmc.edu and http://www.sanger.ac.uk/Projects/D_discoideum/) from the genome sequencing and assembly centers, these improvements have expanded the scope of the Dictyostelium databases making them accessible and useful to any researcher interested in comparative and functional genomics in metazoan organisms.


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