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Nucleic Acids Research, 2004, Vol. 32, Database issue D505-D508
© 2004 Oxford University Press

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system

Detlev Bannasch*, Alexander Mehrle, Karl-Heinz Glatting1, Rainer Pepperkok2, Annemarie Poustka and Stefan Wiemann

German Cancer Research Center (DKFZ), Division of Molecular Genome Analysis, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany, 1 German Cancer Research Center (DKFZ), Division of Molecular Biophysics, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany and 2 European Molecular Biology Laboratory (EMBL), Department of Cell Biology and Cell Biophysics, Meyerhofstrasse 1, D-69117 Heidelberg, Germany

*To whom correspondence should be addressed. Tel: +49 6221 424711; Fax: +49 6221 423454; Email: d.bannasch{at}dkfz.de
Correspondence may be also addressed to Alexander Mehrle. Tel: +49 6221 424711; Fax: +49 6221 423454; Email: a.mehrle{at}dkfz.de
The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors

We have implemented LIFEdb (http://www.dkfz.de/LIFEdb) to link information regarding novel human full-length cDNAs generated and sequenced by the German cDNA Consortium with functional information on the encoded proteins produced in functional genomics and proteomics approaches. The database also serves as a sample-tracking system to manage the process from cDNA to experimental read-out and data interpretation. A web interface enables the scientific community to explore and visualize features of the annotated cDNAs and ORFs combined with experimental results, and thus helps to unravel new features of proteins with as yet unknown functions.


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