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Nucleic Acids Research, 2004, Vol. 32, Database issue D552-D556
© 2004 Oxford University Press

GenePaint.org: an atlas of gene expression patterns in the mouse embryo

Axel Visel, Christina Thaller1 and Gregor Eichele*

Max Planck Institute of Experimental Endocrinology, Feodor-Lynen-Strasse 7, D-30625 Hannover, Germany and 1 Baylor College of Medicine, Department of Biochemistry and Molecular Biology, One Baylor Plaza, Houston, TX 77030, USA

*To whom correspondence should be addressed. Tel: +49 511 5359 100; Fax: +49 511 5359 186; Email: Gregor.Eichele{at}mpihan.mpg.de

High-throughput instruments were recently developed to determine gene expression patterns on tissue sections by RNA in situ hybridization. The resulting images of gene expression patterns, chiefly of E14.5 mouse embryos, are accessible to the public at http://www.genepaint.org. This relational database is searchable for gene identifiers and RNA probe sequences. Moreover, patterns and intensity of expression in ~100 different embryonic tissues are annotated and can be searched using a standardized catalog of anatomical structures. A virtual microscope tool, the Zoom Image Server, was implemented in GenePaint.org and permits interactive zooming and panning across ~15 000 high-resolution images.


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