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Nucleic Acids Research, 2004, Vol. 32, Database issue D95-D100
© 2004 Oxford University Press

Aptamer Database

Jennifer F. Lee, Jay R. Hesselberth1, Lauren Ancel Meyers2 and Andrew D. Ellington*

Department of Chemistry and Biochemistry, Institute for Cell and Molecular Biology, University of Texas at Austin, 1 University Station A4800, Austin, TX 78712, USA, 1 Department of Genome Sciences, University of Washington, Health Sciences Building K-2222/Box 357730, Seattle, WA 98915, USA and 2 Section of Integrative Biology, University of Texas at Austin, 1 University Station C0930, Austin, TX 78712, USA

*To whom correspondence should be addressed. Tel: +1 512 232 3424; Fax: +1 512 471 7014; Email: andy.ellington{at}mail.utexas.edu

The aptamer database is designed to contain comprehensive sequence information on aptamers and unnatural ribozymes that have been generated by in vitro selection methods. Such data are not normally collected in ‘natural’ sequence databases, such as GenBank. Besides serving as a storehouse of sequences that may have diagnostic or therapeutic utility, the database serves as a valuable resource for theoretical biologists who describe and explore fitness landscapes. The database is updated monthly and is publicly available at http://aptamer. icmb.utexas.edu/.


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