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Nucleic Acids Research 2004 32(Web Server Issue):W10-W15; doi:10.1093/nar/gkh367
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© 2004, the authors
Nucleic Acids Research, Vol. 32, Web Server issue © Oxford University Press 2004; all rights reserved

The web server of IBM's Bioinformatics and Pattern Discovery group: 2004 update

Tien Huynh1 and Isidore Rigoutsos1,2,*

1 Bioinformatics and Pattern Discovery group, IBM T.J. Watson Research Center, PO Box 218, Yorktown Heights, NY 10598, USA and 2 Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

* To whom correspondence should be addressed. Tel: +1 914 945 1384; Fax: 1 914 945 4104; Email: rigoutso{at}us.ibm.com

Received February 14, 2004; Accepted March 8, 2004

In this report, we provide an update on the services and content which are available on the web server of IBM's Bioinformatics and Pattern Discovery group. The server, which is operational around the clock, provides access to a large number of methods that have been developed and published by the group's members. There is an increasing number of problems that these tools can help tackle; these problems range from the discovery of patterns in streams of events and the computation of multiple sequence alignments, to the discovery of genes in nucleic acid sequences, the identification—directly from sequence—of structural deviations from {alpha}-helicity and the annotation of amino acid sequences for antimicrobial activity. Additionally, annotations for more than 130 archaeal, bacterial, eukaryotic and viral genomes are now available on-line and can be searched interactively. The tools and code bundles continue to be accessible from http://cbcsrv.watson.ibm.com/Tspd.html whereas the genomics annotations are available at http://cbcsrv.watson.ibm.com/Annotations/.

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