RDfolder: a web server for prediction of RNA secondary structure
Beijing Institute of Basic Medical Sciences, PO Box 130(3), Beijing 100850, People's Republic of China and 1 Center of Bioinformatics, Peking University, Beijing 100871, People's Republic of China
* To whom correspondence should be addressed. Tel: +86 10 66931324; Fax: +86 10 68213039; Email: liwj{at}nic.bmi.ac.cn
The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors
Received February 15, 2004; Revised and Accepted April 20, 2004
Prediction of RNA secondary structure is important in the functional analysis of RNA molecules. The RDfolder web server described in this paper provides two methods for prediction of RNA secondary structure: random stacking of helical regions and helical regions distribution. The random stacking method predicts secondary structure by Monte Carlo simulations. The method of helical regions distribution predicts secondary structure based on the helices that appear most frequently in the set of structures, which are generated by the random stacking method. The RDfolder web server can be accessed at http://rna.cbi.pku.edu.cn.
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