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Nucleic Acids Research 2004 32(Web Server Issue):W313-W317; doi:10.1093/nar/gkh406
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© 2004, the authors
Nucleic Acids Research, Vol. 32, Web Server issue © Oxford University Press 2004; all rights reserved

GOblet: a platform for Gene Ontology annotation of anonymous sequence data

Detlef Groth, Hans Lehrach and Steffen Hennig*

Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany

* To whom correspondence should be addressed. Tel: +49 30 8413 1612; Fax: +49 30 8413 1380; Email: hennig{at}molgen.mpg.de

Received February 24, 2004; Revised and Accepted March 29, 2004

GOblet is a comprehensive web server application providing the annotation of anonymous sequence data with Gene Ontology (GO) terms. It uses a variety of different protein databases (human, murines, invertebrates, plants, sp-trembl) and their respective GO mappings. The user selects the appropriate database and alignment threshold and thereafter submits single or multiple nucleotide or protein sequences. Results are shown in different ways, e.g. as survey statistics for the main GO categories for all sequences or as detailed results for each single sequence that has been submitted. In its newest version, GOblet allows the batch submission of sequences and provides an improved display of results with the aid of Java applets. All output data, together with the Java applet, are packed to a downloadable archive for local installation and analysis. GOblet can be accessed freely at http://goblet.molgen.mpg.de.

The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated.


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