GOblet: a platform for Gene Ontology annotation of anonymous sequence data
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
* To whom correspondence should be addressed. Tel: +49 30 8413 1612; Fax: +49 30 8413 1380; Email: hennig{at}molgen.mpg.de
Received February 24, 2004; Revised and Accepted March 29, 2004
GOblet is a comprehensive web server application providing the annotation of anonymous sequence data with Gene Ontology (GO) terms. It uses a variety of different protein databases (human, murines, invertebrates, plants, sp-trembl) and their respective GO mappings. The user selects the appropriate database and alignment threshold and thereafter submits single or multiple nucleotide or protein sequences. Results are shown in different ways, e.g. as survey statistics for the main GO categories for all sequences or as detailed results for each single sequence that has been submitted. In its newest version, GOblet allows the batch submission of sequences and provides an improved display of results with the aid of Java applets. All output data, together with the Java applet, are packed to a downloadable archive for local installation and analysis. GOblet can be accessed freely at http://goblet.molgen.mpg.de.
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