BioInfo3D: a suite of tools for structural bioinformatics
School of Computer Science, Raymond and Beverly Sackler Faculty of Exact Sciences and 1 Sackler Institute of Molecular Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel and 2 Basic Research Program, SAIC-Frederick, Inc., Laboratory of Experimental and Computational Biology, NCI-Frederick, Building 469, Room 151, Frederick, MD 21702, USA
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Received February 26, 2004; Revised and Accepted April 2, 2004
Here, we describe BioInfo3D, a suite of freely available web services for protein structural analysis. The FlexProt method performs flexible structural alignment of protein molecules. FlexProt simultaneously detects the hinge regions and aligns the rigid subparts of the molecules. It does not require an a priori knowledge of the flexible hinge regions. MultiProt and MASS perform simultaneous comparison of multiple protein structures. PatchDock performs prediction of protein–protein and protein–small molecule interactions. The input to all services is either protein PDB codes or protein structures uploaded to the server. All the services are available at http://bioinfo3d.cs.tau.ac.il.
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