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Nucleic Acids Research 2004 32(Web Server Issue):W508-W511; doi:10.1093/nar/gkh388
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© 2004, the authors
Nucleic Acids Research, Vol. 32, Web Server issue © Oxford University Press 2004; all rights reserved

SCit: web tools for protein side chain conformation analysis

R. Gautier, A.-C. Camproux and P. Tufféry*

Equipe de Bioinformatique Génomique et Moléculaire, INSERM E346, Université Paris 7, case 7113, 2, place Jussieu, 75251 Paris cedex 05, France

* To whom correspondence should be addressed. Tel: +33 1 44 27 77 33; Fax: +33 1 43 26 38 30; Email: tuffery{at}ebgm.jussieu.fr

Received February 13, 2004; Revised and Accepted March 24, 2004

SCit is a web server providing services for protein side chain conformation analysis and side chain positioning. Specific services use the dependence of the side chain conformations on the local backbone conformation, which is described using a structural alphabet that describes the conformation of fragments of four-residue length in a limited library of structural prototypes. Based on this concept, SCit uses sets of rotameric conformations dependent on the local backbone conformation of each protein for side chain positioning and the identification of side chains with unlikely conformations. The SCit web server is accessible at http://bioserv.rpbs.jussieu.fr/SCit.

The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated.


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