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Nucleic Acids Research 2005 33(Database Issue):D418-D424; doi:10.1093/nar/gki051
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Nucleic Acids Research, 2005, Vol. 33, Database issue D418-D424
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved

The Biomolecular Interaction Network Database and related tools 2005 update

C. Alfarano1, C. E. Andrade1,2, K. Anthony1, N. Bahroos1, M. Bajec1, K. Bantoft1, D. Betel1, B. Bobechko1, K. Boutilier1, E. Burgess1, K. Buzadzija1, R. Cavero1, C. D'Abreo1, I. Donaldson1, D. Dorairajoo2, M. J. Dumontier1, M. R. Dumontier1, V. Earles1, R. Farrall1, H. Feldman1, E. Garderman1, Y. Gong1, R. Gonzaga1, V. Grytsan1, E. Gryz1, V. Gu1, E. Haldorsen1, A. Halupa1, R. Haw1, A. Hrvojic1, L. Hurrell1, R. Isserlin1, F. Jack1, F. Juma1, A. Khan1, T. Kon1, S. Konopinsky1, V. Le1, E. Lee1, S. Ling1, M. Magidin1, J. Moniakis1, J. Montojo1, S. Moore1, B. Muskat1, I. Ng1, J. P. Paraiso1, B. Parker1, G. Pintilie1, R. Pirone1, J. J. Salama1, S. Sgro1, T. Shan1, Y. Shu2, J. Siew2, D. Skinner1, K. Snyder1, R. Stasiuk1, D. Strumpf1, B. Tuekam1, S. Tao2, Z. Wang1, M. White1, R. Willis1, C. Wolting1, S. Wong1, A. Wrong1, C. Xin2, R. Yao1, B. Yates2, S. Zhang1, K. Zheng1, T. Pawson1, B. F. F. Ouellette3 and C. W. V. Hogue1,2,*

1 The Blueprint Initiative of Mount Sinai Hospital, 600 University Avenue, Toronto, ON, Canada M5G 1X5, 2 Department of Biological Sciences, The Blueprint Initiative Asia c/o National University of Singapore, 14 Science Drive 4, Singapore 117543 and 3 UBC Bioinformatics Centre, University of British Columbia, Vancouver, BC, Canada V5Z 4H4

* To whom correspondence should be addressed. Tel: +1 416 596 8505; Fax: +1 416 596 8077; Email: chogue{at}blueprint.org

Received September 16, 2004; Revised and Accepted September 30, 2004

The Biomolecular Interaction Network Database (BIND) (http://bind.ca) archives biomolecular interaction, reaction, complex and pathway information. Our aim is to curate the details about molecular interactions that arise from published experimental research and to provide this information, as well as tools to enable data analysis, freely to researchers worldwide. BIND data are curated into a comprehensive machine-readable archive of computable information and provides users with methods to discover interactions and molecular mechanisms. BIND has worked to develop new methods for visualization that amplify the underlying annotation of genes and proteins to facilitate the study of molecular interaction networks. BIND has maintained an open database policy since its inception in 1999. Data growth has proceeded at a tremendous rate, approaching over 100 000 records. New services provided include a new BIND Query and Submission interface, a Standard Object Access Protocol service and the Small Molecule Interaction Database (http://smid.blueprint.org) that allows users to determine probable small molecule binding sites of new sequences and examine conserved binding residues.


The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use permissions, please contact journals.permissions{at}oupjournals.org.


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