Nucleic Acids Research, 2005, Vol. 33, Database issue D567-D572
© 2005, the authors
Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved
The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms
1 Integrated Database Group, Japan Biological Information Research Center, Japan Biological Informatics Consortium, Time24 Building 10F, 2-45 Aomi, Koto-ku, Tokyo 135-0064, Japan, 2 Integrated Database Group, Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, Time24 Building 10F 2-45 Aomi, Koto-ku, Tokyo 135-0064 Japan, 3 Genexpress, Functional Genomics and Systemic Biology for Health, CNRS FRE 2571, 7 rue Guy-Moquet, BP 8, 94801 Villejuif Cedex, France, 4 BITS Co., Ltd, 537-1-103 Namiki, Yata, Mishima 411-0801, Japan, 5 Functional Genomics Group, Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, 2-41-6 Aomi, Koto-ku, Tokyo 135-0064, Japan, 6 Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan, 7 Hitachi Science Systems Co., Ltd, 1040 Ichige, Hitachinaka, Ibaraki 312-0033, Japan, 8 Nara Institute of Science and Technology, 8916-5, Takayama-cho, Ikoma-shi, Nara 630-0101, Japan, 9 Human Genome Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku Tokyo 108-8639, Japan, 10 Ludwig Institute for Cancer Research, Sao Paulo Branch, Rua Prof. Antonio Prudente 109-4 andar Sao Paulo, 01509-010, SP, Brazil, 11 Sino-French Laboratory in Life Sciences and Genomics, 197 Rui-Jin Er Road, Shanghai 200025, China, 12 Ashigara Research Laboratories, Fuji Film Co., Ltd, 210 Nakanuma, Minami-Ashigara, Kanagawa 250-0193, Japan, 13 South African National Bioinformatics Institute, University of the Western Cape, Bellville 7535, South Africa and 14 Department of Genetics, The Graduate University for Advanced Studies, 1111 Yata, Mishima. Shizuoka 411-8540, Japan
* To whom correspondence should be addressed. Tel: +81 3 5531 8550; Fax: +81 3 5531 8551; Email: mtanino{at}jbirc.aist.go.jp
Received August 20, 2004; Revised and Accepted October 15, 2004
The Human Anatomic Gene Expression Library (H-ANGEL) is a resource for information concerning the anatomical distribution and expression of human gene transcripts. The tool contains protein expression data from multiple platforms that has been associated with both manually annotated full-length cDNAs from H-InvDB and RefSeq sequences. Of the H-Inv predicted genes, 18 897 have associated expression data generated by at least one platform. H-ANGEL utilizes categorized mRNA expression data from both publicly available and proprietary sources. It incorporates data generated by three types of methods from seven different platforms. The data are provided to the user in the form of a web-based viewer with numerous query options. H-ANGEL is updated with each new release of cDNA and genome sequence build. In future editions, we will incorporate the capability for expression data updates from existing and new platforms. H-ANGEL is accessible at http://www.jbirc.aist.go.jp/hinv/h-angel/.
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use permissions, please contact journals.permissions{at}oupjournals.org.
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