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Nucleic Acids Research 2005 33(Web Server Issue):W130-W132; doi:10.1093/nar/gki427
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© The Author 2005. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions{at}oupjournals.org

Article

DIAL: a web-based server for the automatic identification of structural domains in proteins

Ganesan Pugalenthi, Govindaraju Archunan1 and Ramanathan Sowdhamini*

National Centre for Biological Sciences, Tata Institute of Fundamental Research UAS-GKVK campus, Bellary Road, Bangalore 560 065, Karnataka, India 1Department of Animal Science, Bharathidasan University Trichirapalli, Tamilnadu, 620 024, India

*To whom correspondence should be addressed. Tel: +91 80 23636421 Ext. 4240/1; Fax: +91 80 23636462; Email: mini{at}ncbs.res.in

Received February 14, 2005. Revised March 24, 2005. Accepted March 24, 2005.

DIAL is a web server for the automatic identification of structural domains given the 3D coordinates of a protein. Delineation of the structural domains and their exact boundaries are the starting points for the better realization of distantly related members of the domain families, for the rational design of the experiments and for clearer understanding of the biological function. The current server can examine crystallographic multiple chains and provide structural domain solutions that can also describe domain swapping events. The server can be accessed from http://www.ncbs.res.in/~faculty/mini/DIAL/home.html. The Supplementary data can be accessed from http://www.ncbs.res.in/~faculty/mini/DIAL/supplement.html.


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