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BIOVERSE: enhancements to the framework for structural, functional and contextual modeling of proteins and proteomes
Department of Microbiology, University of Washington Seattle, WA, USA
*To whom correspondence should be addressed. Tel: +1 206 732 6122; Fax: +1 206 732 6055; Email: ram{at}compbio.washington.edu
Received February 14, 2005. Revised March 16, 2005. Accepted March 16, 2005.
We have made a number of enhancements to the previously described Bioverse web server and computational biology framework (http://bioverse.compbio.washington.edu). In this update, we provide an overview of the new features available that include: (i) expansion of the number of organisms represented in the Bioverse and addition of new data sources and novel prediction techniques not available elsewhere, including network-based annotation; (ii) reengineering the database backend and supporting code resulting in significant speed, search and ease-of use improvements; and (iii) creation of a stateful and dynamic web application frontend to improve interface speed and usability. Integrated Java-based applications also allow dynamic visualization of real and predicted protein interaction networks.
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