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Nucleic Acids Research 2006 34(Database Issue):D104-D107; doi:10.1093/nar/gkj113
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Nucleic Acids Research, 2006, Vol. 34, Database issue D104-D107
© The Author 2006. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions{at}oxfordjournals.org

Article

TiProD: the Tissue-specific Promoter Database

Xin Chen, Jian-min Wu, Klaus Hornischer1, Alexander Kel1 and Edgar Wingender1,2,*

Centre of Bioinformatics, College of Life Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University Beijing 100871, China 1BIOBASE GmbH Halchtersche Strasse 33, D-38304 Wolfenbüttel, Germany 2Department of Bioinformatics, UKG, University of Göttingen Goldschmidtstrasse 1, D-37077 Göttingen, Germany

*To whom correspondence should be addressed. Tel: +49 (0) 551 39 14912; Fax: +49 (0) 551 39 14914; Email: edgar.wingender{at}bioinf.med.uni-goettingen.de

Received August 12, 2005. Revised October 7, 2005. Accepted October 18, 2005.

TiProD is a database of human promoter sequences for which some functional features are known. It allows a user to query individual promoters and the expression pattern they mediate, gene expression signatures of individual tissues, and to retrieve sets of promoters according to their tissue-specific activity or according to individual Gene Ontology terms the corresponding genes are assigned to. We have defined a measure for tissue-specificity that allows the user to discriminate between ubiquitously and specifically expressed genes. The database is accessible at http://tiprod.cbi.pku.edu.cn:8080/index.html.


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