Article |
SMART 5: domains in the context of genomes and networks
EMBL Meyerhofstrasse 1, 69012 Heidelberg, Germany 1Wellcome Trust Centre for Human Genetics Roosevelt Drive, Oxford OX3 7BN, UK 2Bioinformatik, Biozentrum, Am Hubland, University of Wuerzburg 97074 Wuerzburg, Germany
*To whom correspondence should be addressed. Tel: +49 6221 387 8526; Fax: +49 6221 387 517; Email: bork{at}embl.de
Received September 13, 2005. Revised October 11, 2005. Accepted October 11, 2005.
The Simple Modular Architecture Research Tool (SMART) is an online resource (http://smart.embl.de/) used for protein domain identification and the analysis of protein domain architectures. Many new features were implemented to make SMART more accessible to scientists from different fields. The new ‘Genomic’ mode in SMART makes it easy to analyze domain architectures in completely sequenced genomes. Domain annotation has been updated with a detailed taxonomic breakdown and a prediction of the catalytic activity for 50 SMART domains is now available, based on the presence of essential amino acids. Furthermore, intrinsically disordered protein regions can be identified and displayed. The network context is now displayed in the results page for more than 350 000 proteins, enabling easy analyses of domain interactions.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  S. Krauss, J. Kaps, N. Czech, C. Paulus, and M. Nevels Physical Requirements and Functional Consequences of Complex Formation between the Cytomegalovirus IE1 Protein and Human STAT2 J. Virol., December 15, 2009; 83(24): 12854 - 12870. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Beckstette, R. Homann, R. Giegerich, and S. Kurtz Significant speedup of database searches with HMMs by search space reduction with PSSM family models Bioinformatics, December 15, 2009; 25(24): 3251 - 3258. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Abdesselem, A. Shypitsyna, G. P. Solis, V. Bodrikov, and C. A. O. Stuermer No Nogo66- and NgR-Mediated Inhibition of Regenerating Axons in the Zebrafish Optic Nerve J. Neurosci., December 9, 2009; 29(49): 15489 - 15498. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Werden, J. Lanchbury, D. Shattuck, C. Neff, M. Dufford, and G. McFadden The Myxoma Virus M-T5 Ankyrin Repeat Host Range Protein Is a Novel Adaptor That Coordinately Links the Cellular Signaling Pathways Mediated by Akt and Skp1 in Virus-Infected Cells J. Virol., December 1, 2009; 83(23): 12068 - 12083. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Jin, X. Xie, C. Chen, J. G. Park, C. Stark, D. A. James, M. Olhovsky, R. Linding, Y. Mao, and T. Pawson Eukaryotic Protein Domains as Functional Units of Cellular Evolution Sci. Signal., November 24, 2009; 2(98): ra76 - ra76. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. A. Lee, R. Rentzsch, and C. Orengo GeMMA: functional subfamily classification within superfamilies of predicted protein structural domains Nucleic Acids Res., November 18, 2009; (2009) gkp1049v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. W. Sayers, T. Barrett, D. A. Benson, E. Bolton, S. H. Bryant, K. Canese, V. Chetvernin, D. M. Church, M. DiCuccio, S. Federhen, et al. Database resources of the National Center for Biotechnology Information Nucleic Acids Res., November 12, 2009; (2009) gkp967v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Yu. Lobanov, B. A. Shoemaker, S. O. Garbuzynskiy, J. H. Fong, A. R. Panchenko, and O. V. Galzitskaya ComSin: database of protein structures in bound (complex) and unbound (single) states in relation to their intrinsic disorder Nucleic Acids Res., November 11, 2009; (2009) gkp963v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Rancurel, M. Khosravi, A. K. Dunker, P. R. Romero, and D. Karlin Overlapping Genes Produce Proteins with Unusual Sequence Properties and Offer Insight into De Novo Protein Creation J. Virol., October 15, 2009; 83(20): 10719 - 10736. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. D. Brown, S. Tiozzo, M. M. Roux, K. Ishizuka, B. J. Swalla, and A. W. De Tomaso Early lineage specification of long-lived germline precursors in the colonial ascidian Botryllus schlosseri Development, October 15, 2009; 136(20): 3485 - 3494. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. T. Longhi, T. R. Oliveira, E. C. Romero, A. P. Goncales, Z. M. de Morais, S. A. Vasconcellos, and A. L. T. O. Nascimento A newly identified protein of Leptospira interrogans mediates binding to laminin J. Med. Microbiol., October 1, 2009; 58(10): 1275 - 1282. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Jalasvuori, S. T. Jaatinen, S. Laurinavicius, E. Ahola-Iivarinen, N. Kalkkinen, D. H. Bamford, and J. K. H. Bamford The Closest Relatives of Icosahedral Viruses of Thermophilic Bacteria Are among Viruses and Plasmids of the Halophilic Archaea J. Virol., September 15, 2009; 83(18): 9388 - 9397. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Encinar, G. Fernandez-Ballester, I. E. Sanchez, E. Hurtado-Gomez, F. Stricher, P. Beltrao, and L. Serrano ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs Bioinformatics, September 15, 2009; 25(18): 2418 - 2424. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Van Doorslaer, A. Ould M'hamed Ould Sidi, K. Zanier, V. Rybin, F. Deryckere, A. Rector, R. D. Burk, E. K. Lienau, M. van Ranst, and G. Trave Identification of Unusual E6 and E7 Proteins within Avian Papillomaviruses: Cellular Localization, Biophysical Characterization, and Phylogenetic Analysis J. Virol., September 1, 2009; 83(17): 8759 - 8770. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Jagadeesan, P. Mann, C. W. Schink, and P. I. Higgs A Novel "Four-component" Two-component Signal Transduction Mechanism Regulates Developmental Progression in Myxococcus xanthus J. Biol. Chem., August 7, 2009; 284(32): 21435 - 21445. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. Fong and A. Marchler-Bauer CORAL: aligning conserved core regions across domain families Bioinformatics, August 1, 2009; 25(15): 1862 - 1868. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Yabu, A. Shimuzu, and M. Yamashita A Novel Mitochondrial Sphingomyelinase in Zebrafish Cells J. Biol. Chem., July 24, 2009; 284(30): 20349 - 20363. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Netter, G. Weber, H. Benecke, and M. C. Wahl Functional stabilization of an RNA recognition motif by a noncanonical N-terminal expansion RNA, July 1, 2009; 15(7): 1305 - 1313. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Malet, B. Coutard, S. Jamal, H. Dutartre, N. Papageorgiou, M. Neuvonen, T. Ahola, N. Forrester, E. A. Gould, D. Lafitte, et al. The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket J. Virol., July 1, 2009; 83(13): 6534 - 6545. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. T. M. Mooij, E. Mitsiki, and A. Perrakis ProteinCCD: enabling the design of protein truncation constructs for expression and crystallization experiments Nucleic Acids Res., July 1, 2009; 37(suppl_2): W402 - W405. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Gustin, B.-J. Guan, A. Dziduszko, and D. A. Brian Bovine Coronavirus Nonstructural Protein 1 (p28) Is an RNA Binding Protein That Binds Terminal Genomic cis-Replication Elements J. Virol., June 15, 2009; 83(12): 6087 - 6097. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. R. Mohamed, M. M. Rahman, J. S. Lanchbury, D. Shattuck, C. Neff, M. Dufford, N. van Buuren, K. Fagan, M. Barry, S. Smith, et al. Proteomic screening of variola virus reveals a unique NF-{kappa}B inhibitor that is highly conserved among pathogenic orthopoxviruses PNAS, June 2, 2009; 106(22): 9045 - 9050. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Ghosh, K. Chakrabarti, and D. Chattopadhyay Cloning of feather-degrading minor extracellular protease from Bacillus cereus DCUW: dissection of the structural domains Microbiology, June 1, 2009; 155(6): 2049 - 2057. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. J. Ipsaro, L. Huang, and A. Mondragon Structures of the spectrin-ankyrin interaction binding domains Blood, May 28, 2009; 113(22): 5385 - 5393. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Rezvani, Y. Teng, Y. Pan, J. A. Dani, J. Lindstrom, E. A. Garcia Gras, J. M. McIntosh, and M. De Biasi UBXD4, a UBX-Containing Protein, Regulates the Cell Surface Number and Stability of {alpha}3-Containing Nicotinic Acetylcholine Receptors J. Neurosci., May 27, 2009; 29(21): 6883 - 6896. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Miyakawa, A. Okamuro, S. Kinsky, K. Visacka, L. Tomaska, and J. Nosek Mitochondrial nucleoids from the yeast Candida parapsilosis: expansion of the repertoire of proteins associated with mitochondrial DNA Microbiology, May 1, 2009; 155(5): 1558 - 1568. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. Lehti-Shiu, C. Zou, K. Hanada, and S.-H. Shiu Evolutionary History and Stress Regulation of Plant Receptor-Like Kinase/Pelle Genes Plant Physiology, May 1, 2009; 150(1): 12 - 26. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Lian, Y. Wang, M. Flick, J. Choi, E. W. Scott, J. Degen, M. A. Lemmon, and C. S. Abrams Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis Blood, April 9, 2009; 113(15): 3577 - 3584. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Visacka, J. M. Gerhold, J. Petrovicova, S. Kinsky, P. Joers, J. Nosek, J. Sedman, and L. Tomaska Novel subfamily of mitochondrial HMG box-containing proteins: functional analysis of Gcf1p from Candida albicans Microbiology, April 1, 2009; 155(4): 1226 - 1240. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Chatre, L. A. Matheson, A. S. Jack, S. L. Hanton, and F. Brandizzi Efficient mitochondrial targeting relies on co-operation of multiple protein signals in plants J. Exp. Bot., March 1, 2009; 60(3): 741 - 749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. R. Evans, P. B. Card, and K. H. Gardner ARNT PAS-B has a fragile native state structure with an alternative {beta}-sheet register nearby in sequence space PNAS, February 24, 2009; 106(8): 2617 - 2622. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. V. Patankar and J. E. Gonzalez An Orphan LuxR Homolog of Sinorhizobium meliloti Affects Stress Adaptation and Competition for Nodulation Appl. Envir. Microbiol., February 15, 2009; 75(4): 946 - 955. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. D. Hay, U. Remminghorst, and B. H. A. Rehm MucR, a Novel Membrane-Associated Regulator of Alginate Biosynthesis in Pseudomonas aeruginosa Appl. Envir. Microbiol., February 15, 2009; 75(4): 1110 - 1120. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Bondugula, M. S. Lee, and A. Wallqvist FIEFDom: a transparent domain boundary recognition system using a fuzzy mean operator Nucleic Acids Res., February 1, 2009; 37(2): 452 - 462. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. H. Singh, T. Doerks, I. Letunic, J. Raes, and P. Bork Discovering Functional Novelty in Metagenomes: Examples from Light-Mediated Processes J. Bacteriol., January 1, 2009; 191(1): 32 - 41. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Iida, T. Waki, K. Nakamura, Y. Mukouzaka, and T. Kudo The GAF-Like-Domain-Containing Transcriptional Regulator DfdR Is a Sensor Protein for Dibenzofuran and Several Hydrophobic Aromatic Compounds J. Bacteriol., January 1, 2009; 191(1): 123 - 134. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Diella, S. Chabanis, K. Luck, C. Chica, C. Ramu, C. Nerlov, and T. J. Gibson KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors Bioinformatics, January 1, 2009; 25(1): 1 - 5. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. W. Sayers, T. Barrett, D. A. Benson, S. H. Bryant, K. Canese, V. Chetvernin, D. M. Church, M. DiCuccio, R. Edgar, S. Federhen, et al. Database resources of the National Center for Biotechnology Information Nucleic Acids Res., January 1, 2009; 37(suppl_1): D5 - D15. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Hunter, R. Apweiler, T. K. Attwood, A. Bairoch, A. Bateman, D. Binns, P. Bork, U. Das, L. Daugherty, L. Duquenne, et al. InterPro: the integrative protein signature database Nucleic Acids Res., January 1, 2009; 37(suppl_1): D211 - D215. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Letunic, T. Doerks, and P. Bork SMART 6: recent updates and new developments Nucleic Acids Res., January 1, 2009; 37(suppl_1): D229 - D232. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Marchler-Bauer, J. B. Anderson, F. Chitsaz, M. K. Derbyshire, C. DeWeese-Scott, J. H. Fong, L. Y. Geer, R. C. Geer, N. R. Gonzales, M. Gwadz, et al. CDD: specific functional annotation with the Conserved Domain Database Nucleic Acids Res., January 1, 2009; 37(suppl_1): D205 - D210. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Richardson, Q. Gao, C. Mitsopoulous, M. Zvelebil, L. H. Pearl, and F. M. G. Pearl MoKCa database--mutations of kinases in cancer Nucleic Acids Res., January 1, 2009; 37(suppl_1): D824 - D831. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Wilson, R. Pethica, Y. Zhou, C. Talbot, C. Vogel, M. Madera, C. Chothia, and J. Gough SUPERFAMILY--sophisticated comparative genomics, data mining, visualization and phylogeny Nucleic Acids Res., January 1, 2009; 37(suppl_1): D380 - D386. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. V. Elias, R. Quiroga, N. Gottig, H. Nakanishi, T. E. Nash, A. Neiman, and H. D. Lujan Characterization of SNAREs Determines the Absence of a Typical Golgi Apparatus in the Ancient Eukaryote Giardia lamblia J. Biol. Chem., December 19, 2008; 283(51): 35996 - 36010. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. M. Sansom, S. C. Robson, and E. L. Hartland Possible Effects of Microbial Ecto-Nucleoside Triphosphate Diphosphohydrolases on Host-Pathogen Interactions Microbiol. Mol. Biol. Rev., December 1, 2008; 72(4): 765 - 781. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. G. Brown, E. H. Mitchell, and D. L. Balkwill Tet 42, a Novel Tetracycline Resistance Determinant Isolated from Deep Terrestrial Subsurface Bacteria Antimicrob. Agents Chemother., December 1, 2008; 52(12): 4518 - 4521. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Hu, J. Xing, L. Chen, X. Guo, Y. Du, C. Zhao, Y. Zhu, M. Lin, Z. Zhou, and J. Sha RGS22, A Novel Testis-Specific Regulator of G-protein Signaling Involved in Human and Mouse Spermiogenesis along with GNA12/13 Subunits Biol Reprod, December 1, 2008; 79(6): 1021 - 1029. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Chalkia, N. Nikolaidis, W. Makalowski, J. Klein, and M. Nei Origins and Evolution of the Formin Multigene Family That Is Involved in the Formation of Actin Filaments Mol. Biol. Evol., December 1, 2008; 25(12): 2717 - 2733. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. J. Munoz-Elias, J. Marcano, and A. Camilli Isolation of Streptococcus pneumoniae Biofilm Mutants and Their Characterization during Nasopharyngeal Colonization Infect. Immun., November 1, 2008; 76(11): 5049 - 5061. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Hiwatashi, M. Obara, Y. Sato, T. Fujita, T. Murata, and M. Hasebe Kinesins Are Indispensable for Interdigitation of Phragmoplast Microtubules in the Moss Physcomitrella patens PLANT CELL, November 1, 2008; 20(11): 3094 - 3106. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Paterson, C. A. Ydenberg, and M. D. Rose Dynamic localization of yeast Fus2p to an expanding ring at the cell fusion junction during mating J. Cell Biol., October 17, 2008; 181(4): 697 - 709. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Colomina, F. Ferrezuelo, H. Wang, M. Aldea, and E. Gari Whi3, a Developmental Regulator of Budding Yeast, Binds a Large Set of mRNAs Functionally Related to the Endoplasmic Reticulum J. Biol. Chem., October 17, 2008; 283(42): 28670 - 28679. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Vestergaard, S. A. Shah, A. Bize, W. Reitberger, M. Reuter, H. Phan, A. Briegel, R. Rachel, R. A. Garrett, and D. Prangishvili Stygiolobus Rod-Shaped Virus and the Interplay of Crenarchaeal Rudiviruses with the CRISPR Antiviral System J. Bacteriol., October 15, 2008; 190(20): 6837 - 6845. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Ruiz, P. Salinas, M. L. Lopez-Redondo, M. L. Cayuela, A. Marina, and A. Contreras Phosphorylation-independent activation of the atypical response regulator NblR Microbiology, October 1, 2008; 154(10): 3002 - 3015. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. K. Shimizu, T. Ito, S. Ishiguro, and K. Okada MAA3 (MAGATAMA3) Helicase Gene is Required for Female Gametophyte Development and Pollen Tube Guidance in Arabidopsis thaliana Plant Cell Physiol., October 1, 2008; 49(10): 1478 - 1483. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Przybylski and B. Rost Powerful fusion: PSI-BLAST and consensus sequences Bioinformatics, September 15, 2008; 24(18): 1987 - 1993. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. An, J. B. Blumer, M. L. Bernard, and S. M. Lanier The PDZ and Band 4.1 Containing Protein Frmpd1 Regulates the Subcellular Location of Activator of G-protein Signaling 3 and Its Interaction with G-proteins J. Biol. Chem., September 5, 2008; 283(36): 24718 - 24728. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L. Miller, L. J. Jensen, F. Diella, C. Jorgensen, M. Tinti, L. Li, M. Hsiung, S. A. Parker, J. Bordeaux, T. Sicheritz-Ponten, et al. Linear Motif Atlas for Phosphorylation-Dependent Signaling Sci. Signal., September 2, 2008; 1(35): ra2 - ra2. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. Tudor, J. J. Davis, M. Panichella, and A. Zwolak Isolation of Predation-Deficient Mutants of Bdellovibrio bacteriovorus by Using Transposon Mutagenesis Appl. Envir. Microbiol., September 1, 2008; 74(17): 5436 - 5443. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Wang, P. C. Hanington, M. Belosevic, and C. J. Secombes Two Macrophage Colony-Stimulating Factor Genes Exist in Fish That Differ in Gene Organization and Are Differentially Expressed J. Immunol., September 1, 2008; 181(5): 3310 - 3322. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. D. Malone, K. A. Falkowska, A. Y. Li, S. E. Galanti, R. C. Kanuru, E. G. LaMont, K. C. Mazzarella, A. J. Micev, M. M. Osman, N. K. Piotrowski, et al. Nucleus-Specific Importin Alpha Proteins and Nucleoporins Regulate Protein Import and Nuclear Division in the Binucleate Tetrahymena thermophila Eukaryot. Cell, September 1, 2008; 7(9): 1487 - 1499. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Spatuzza, M. Schiavone, E. Di Salle, E. Janda, M. Sardiello, G. Fiume, O. Fierro, M. Simonetta, N. Argiriou, R. Faraonio, et al. Physical and functional characterization of the genetic locus of IBtk, an inhibitor of Bruton's tyrosine kinase: evidence for three protein isoforms of IBtk Nucleic Acids Res., August 1, 2008; 36(13): 4402 - 4416. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. B. Quintaje and S. Orchard The Annotation of Both Human and Mouse Kinomes in UniProtKB/Swiss-Prot: One Small Step in Manual Annotation, One Giant Leap for Full Comprehension of Genomes Mol. Cell. Proteomics, August 1, 2008; 7(8): 1409 - 1419. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Schallus, C. Jaeckh, K. Feher, A. S. Palma, Y. Liu, J. C. Simpson, M. Mackeen, G. Stier, T. J. Gibson, T. Feizi, et al. Malectin: A Novel Carbohydrate-binding Protein of the Endoplasmic Reticulum and a Candidate Player in the Early Steps of Protein N-Glycosylation Mol. Biol. Cell, August 1, 2008; 19(8): 3404 - 3414. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. N. Moschou, M. Sanmartin, A. H. Andriopoulou, E. Rojo, J. J. Sanchez-Serrano, and K. A. Roubelakis-Angelakis Bridging the Gap between Plant and Mammalian Polyamine Catabolism: A Novel Peroxisomal Polyamine Oxidase Responsible for a Full Back-Conversion Pathway in Arabidopsis Plant Physiology, August 1, 2008; 147(4): 1845 - 1857. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Pincus, I. Letunic, P. Bork, and W. A. Lim From the Cover: Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages PNAS, July 15, 2008; 105(28): 9680 - 9684. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Katoh and H. Toh Recent developments in the MAFFT multiple sequence alignment program Brief Bioinform, July 1, 2008; 9(4): 286 - 298. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. I. Higgs, S. Jagadeesan, P. Mann, and D. R. Zusman EspA, an Orphan Hybrid Histidine Protein Kinase, Regulates the Timing of Expression of Key Developmental Proteins of Myxococcus xanthus J. Bacteriol., July 1, 2008; 190(13): 4416 - 4426. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. F. W. Saunders and B. Kobe The Predikin webserver: improved prediction of protein kinase peptide specificity using structural information Nucleic Acids Res., July 1, 2008; 36(suppl_2): W286 - W290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Li, C. Wu, H. Huang, K. Zhang, J. Gan, and S. S.-C. Li Prediction of phosphotyrosine signaling networks using a scoring matrix-assisted ligand identification approach Nucleic Acids Res., June 1, 2008; 36(10): 3263 - 3273. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Yamakawa, C. Pennelegion, S. Willcocks, A. Stalker, N. MacHugh, D. Burt, T. J. Coffey, and D. Werling Identification and functional characterization of a bovine orthologue to DC-SIGN J. Leukoc. Biol., June 1, 2008; 83(6): 1396 - 1403. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Akagi, J. Li, R. M. Stephens, N. Volfovsky, and D. E. Symer Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition Genome Res., June 1, 2008; 18(6): 869 - 880. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. van Rooijen, R. H. Giles, E. E. Voest, C. van Rooijen, S. Schulte-Merker, and F. J. van Eeden LRRC50, a Conserved Ciliary Protein Implicated in Polycystic Kidney Disease J. Am. Soc. Nephrol., June 1, 2008; 19(6): 1128 - 1138. [Full Text] [PDF]
|
|
|
|
|
|
S. Eys, D. Schwartz, W. Wohlleben, and E. Schinko Three Thioesterases Are Involved in the Biosynthesis of Phosphinothricin Tripeptide in Streptomyces viridochromogenes Tu494 Antimicrob. Agents Chemother., May 1, 2008; 52(5): 1686 - 1696. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Lloret-Llinares, C. Carre, A. Vaquero, N. de Olano, and F. Azorin Characterization of Drosophila melanogaster JmjC+N histone demethylases Nucleic Acids Res., May 1, 2008; 36(9): 2852 - 2863. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. R Copley The animal in the genome: comparative genomics and evolution Phil Trans R Soc B, April 27, 2008; 363(1496): 1453 - 1461. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Anderson, J. Rodriguez, D. Susanti, I. Porat, C. Reich, L. E. Ulrich, J. G. Elkins, K. Mavromatis, A. Lykidis, E. Kim, et al. Genome Sequence of Thermofilum pendens Reveals an Exceptional Loss of Biosynthetic Pathways without Genome Reduction J. Bacteriol., April 15, 2008; 190(8): 2957 - 2965. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. W. Heath and R. H. Insall Dictyostelium MEGAPs: F-BAR domain proteins that regulate motility and membrane tubulation in contractile vacuoles J. Cell Sci., April 1, 2008; 121(7): 1054 - 1064. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Frittoli, A. Palamidessi, A. Pizzigoni, L. Lanzetti, M. Garre, F. Troglio, A. Troilo, M. Fukuda, P. P. Di Fiore, G. Scita, et al. The Primate-specific Protein TBC1D3 Is Required for Optimal Macropinocytosis in a Novel ARF6-dependent Pathway Mol. Biol. Cell, April 1, 2008; 19(4): 1304 - 1316. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Gauntlett, S. Gebhard, S. Keis, J. M. Manson, K. M. Pos, and G. M. Cook Molecular Analysis of BcrR, a Membrane-bound Bacitracin Sensor and DNA-binding Protein from Enterococcus faecalis J. Biol. Chem., March 28, 2008; 283(13): 8591 - 8600. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Avisar, A. I. Prokhnevsky, and V. V. Dolja Class VIII Myosins Are Required for Plasmodesmatal Localization of a Closterovirus Hsp70 Homolog J. Virol., March 15, 2008; 82(6): 2836 - 2843. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Geng, J. B. Bruhn, K. F. Nielsen, L. Gram, and R. Belas Genetic Dissection of Tropodithietic Acid Biosynthesis by Marine Roseobacters Appl. Envir. Microbiol., March 1, 2008; 74(5): 1535 - 1545. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. K. Basu, L. Carmel, I. B. Rogozin, and E. V. Koonin Evolution of protein domain promiscuity in eukaryotes Genome Res., March 1, 2008; 18(3): 449 - 461. [Abstract] [Full Text] [PDF]
|
|