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Nucleic Acids Research 2006 34(Database Issue):D407-D410; doi:10.1093/nar/gkj134
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Nucleic Acids Research, 2006, Vol. 34, Database issue D407-D410
© The Author 2006. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions{at}oxfordjournals.org


Article

The UCSC Archaeal Genome Browser

Kevin L. Schneider, Katherine S. Pollard, Robert Baertsch, Andy Pohl and Todd M. Lowe*

Biomolecular Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA

*To whom correspondence should be addressed. Tel: +1 831 459 1511; Fax: +1 831 459 4829; Email: lowe{at}soe.ucsc.edu

Received August 12, 2005. Revised October 27, 2005. Accepted October 27, 2005.

As more archaeal genomes are sequenced, effective research and analysis tools are needed to integrate the diverse information available for any given locus. The feature-rich UCSC Genome Browser, created originally to annotate the human genome, can be applied to any sequenced organism. We have created a UCSC Archaeal Genome Browser, available at http://archaea.ucsc.edu/, currently with 26 archaeal genomes. It displays G/C content, gene and operon annotation from multiple sources, sequence motifs (promoters and Shine-Dalgarno), microarray data, multi-genome alignments and protein conservation across phylogenetic and habitat categories. We encourage submission of new experimental and bioinformatic analysis from contributors. The purpose of this tool is to aid biological discovery and facilitate greater collaboration within the archaeal research community.


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