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Nucleic Acids Research 2006 34(Database Issue):D423-D427; doi:10.1093/nar/gkj090
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Nucleic Acids Research, 2006, Vol. 34, Database issue D423-D427
© The Author 2006. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions{at}oxfordjournals.org

Article

dictyBase, the model organism database for Dictyostelium discoideum

Rex L. Chisholm*, Pascale Gaudet, Eric M. Just, Karen E. Pilcher, Petra Fey, Sohel N. Merchant and Warren A. Kibbe

dictyBase, Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University Chicago, IL 60611, USA

*To whom correspondence should be addressed. Tel: +1 312 503 3209; Fax: +1 312 503 5603; Email: r-chisholm{at}northwestern.edu

Received September 14, 2005. Revised October 13, 2005. Accepted October 13, 2005.

dictyBase (http://dictybase.org) is the model organism database (MOD) for the social amoeba Dictyostelium discoideum. The unique biology and phylogenetic position of Dictyostelium offer a great opportunity to gain knowledge of processes not characterized in other organisms. The recent completion of the 34 MB genome sequence, together with the sizable scientific literature using Dictyostelium as a research organism, provided the necessary tools to create a well-annotated genome. dictyBase has leveraged software developed by the Saccharomyces Genome Database and the Generic Model Organism Database project. This has reduced the time required to develop a full-featured MOD and greatly facilitated our ability to focus on annotation and providing new functionality. We hope that manual curation of the Dictyostelium genome will facilitate the annotation of other genomes.


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