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Nucleic Acids Research 2006 34(Database Issue):D471-D474; doi:10.1093/nar/gkj036
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Nucleic Acids Research, 2006, Vol. 34, Database issue D471-D474
© The Author 2006. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions{at}oxfordjournals.org

Article

SGCEdb: a flexible database and web interface integrating experimental results and analysis for structural genomics focusing on Caenorhabditis elegans

David H. Johnson1, Jun Tsao1,2, Ming Luo1,2 and Mike Carson1,3,*

1Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham Birmingham, AL, USA 2Department of Microbiology, University of Alabama at Birmingham Birmingham, AL, USA 3Department of Biomedical Engineering, University of Alabama at Birmingham Birmingham, AL, USA

*To whom correspondence should be addressed. Tel: +1 205 934 1983; Fax: +1 205 975 0538; Email: carson{at}uab.edu

Received August 13, 2005. Revised September 26, 2005. Accepted September 26, 2005.

The SGCEdb (http://sgce.cbse.uab.edu) database/interface serves the primary purpose of reporting progress of the Structural Genomics of Caenorhabditis elegans project at the University of Alabama at Birmingham. It stores and analyzes results of experiments ranging from solubility screening arrays to individual protein purification and structure solution. External databases and algorithms are referenced and evaluated for target selection in the human, C.elegans and Pneumocystis carinii genomes. The flexible and reusable design permits tracking of standard and custom experiment types in a scientist-defined sequence. The database coordinates efforts between collaborators and is adaptable to a wide range of biological applications.

Correspondence may also be addressed to Ming Luo. Tel: +1 205 934 4259; Fax: +1 205 975 9578; Email: mingluo{at}uab.edu


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