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Ensembl 2006
European Bioinformatics Institute (EMBL-EBI) Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK 1Wellcome Trust Sanger Institute Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
*To whom correspondence should be addressed. Tel: +44 1223 494420; Fax: +44 1223 494470; Email: birney{at}ebi.ac.uk
Received September 14, 2005. Revised October 25, 2005. Accepted October 25, 2005.
The Ensembl (http://www.ensembl.org/) project provides a comprehensive and integrated source of annotation of large genome sequences. Over the last year the number of genomes available from the Ensembl site has increased from 4 to 19, with the addition of the mammalian genomes of Rhesus macaque and Opossum, the chordate genome of Ciona intestinalis and the import and integration of the yeast genome. The year has also seen extensive improvements to both data analysis and presentation, with the introduction of a redesigned website, the addition of RNA gene and regulatory annotation and substantial improvements to the integration of human genome variation data.
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