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Nucleic Acids Research 2006 34(Database Issue):D628-D631; doi:10.1093/nar/gkj137
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Nucleic Acids Research, 2006, Vol. 34, Database issue D628-D631
© The Author 2006. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions{at}oxfordjournals.org

Article

BodyMap-Xs: anatomical breakdown of 17 million animal ESTs for cross-species comparison of gene expression

Osamu Ogasawara1, Makiko Otsuji1, Kouji Watanabe1, Takayasu Iizuka1, Takuro Tamura1, Teruyoshi Hishiki2, Shoko Kawamoto3 and Kousaku Okubo1,2,*

1Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics 1111 Yata, Mishima, Shizuoka 411-8540, Japan 2Biological Information Research Center, National Institute of Advanced Industrial Science and Technology (AIST) 2-42 Aomi, Koto, Tokyo 135-0064, Japan 3National Institute of Informatics 2-1-2 Hitotsubashi, Chiyoda-ku, Tokyo 101-8430, Japan

*To whom correspondence should be addressed. Tel: +81 559 815 838; Fax: +81 559 815 837; E-mail: kokubo{at}genes.nig.ac.jp

Received August 15, 2005. Revised October 27, 2005. Accepted October 27, 2005.

BodyMap-Xs (http://bodymap.jp) is a database for cross-species gene expression comparison. It was created by the anatomical breakdown of 17 million animal expressed sequence tag (EST) records in DDBJ using a sorting program tailored for this purpose. In BodyMap-Xs, users are allowed to compare the expression patterns of orthologous and paralogous genes in a coherent manner. This will provide valuable insights for the evolutionary study of gene expression and identification of a responsive motif for a particular expression pattern. In addition, starting from a concise overview of the taxonomical and anatomical breakdown of all animal ESTs, users can navigate to obtain gene expression ranking of a particular tissue in a particular animal. This method may lead to the understanding of the similarities and differences between the homologous tissues across animal species. BodyMap-Xs will be automatically updated in synchronization with the major update in DDBJ, which occurs periodically.


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