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Nucleic Acids Research 2006 34(Web Server issue):W444-W447; doi:10.1093/nar/gkl268
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© The Author 2006. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org

Article

ASGS: an alternative splicing graph web service

Durgaprasad Bollina1, Bernett T. K. Lee2, Tin Wee Tan2 and Shoba Ranganathan1,2,*

1 Department of Chemistry and Biomolecular Sciences and Biotechnology Research Institute, Macquarie University Sydney, NSW 2109, Australia 2 Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore Singapore, 119260

*To whom correspondence should be addressed. Tel: +61 2 9850 6262; Fax: +61 2 9850 8313; Email: shoba{at}els.mq.edu.au

Received February 14, 2006. Revised March 1, 2006. Accepted March 31, 2006.

Alternative transcript diversity manifests itself a prime cause of complexity in higher eukaryotes. The Alternative Splicing Graph Server (ASGS) is a web service facilitating the systematic study of alternatively spliced genes of higher eukaryotes by generating splicing graphs for the compact visual representation of transcript diversity from a single gene. Taking a set of transcripts in General Feature Format as input, ASGS identifies distinct reference and variable exons, generates a transcript splicing graph, an exon summary, splicing events classification and a single line graph to facilitate experimental analysis. This freely available web service can be accessed at http://asgs.biolinfo.org.


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