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Nucleic Acids Research 2007 35(Database issue):D280-D286; doi:10.1093/nar/gkl883
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Nucleic Acids Research, 2007, Vol. 35, Database issue D280-D286
© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles

Sharing of worldwide distributed carbohydrate-related digital resources: online connection of the Bacterial Carbohydrate Structure DataBase and GLYCOSCIENCES.de

Philip Toukach, Hiren J Joshi1, René Ranzinger1, Yuri Knirel and Claus-W. von der Lieth1,*

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences 119991 Moscow, Russia 1 German Cancer Research Center, Spectroscopic Department (B090) Molecular Modeling, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany

*To whom correspondence should be addressed. Tel: +49 6221 424541; Fax: +49 6221 42454; Email: w.vonderlieth{at}dkfz.de

Received August 16, 2006. Revised October 11, 2006. Accepted October 11, 2006.

Functional glycomics, the scientific attempt to identify and assign functions to all glycan molecules synthesized by an organism, is an emerging field of science. In recent years, several databases have been started, all aiming to support deciphering the biological function of carbohydrates. However, diverse encoding and storage schemes are in use amongst these databases, significantly hampering the interchange of data. The mutual online access between the Bacterial Carbohydrate Structure DataBase (BCSDB) and the GLYCOSCIENCES.de portal, as a first reported attempt of a structure-based direct interconnection of two glyco-related databases is described. In this approach, users have to learn only one interface, will always have access to the latest data of both services, and will have the results of both searches presented in a consistent way. The establishment of this connection helped to find shortcomings and inconsistencies in the database design and functionality related to underlying data concepts and structural representations. For the maintenance of the databases, duplication of work can be easily avoided, and will hopefully lead to a better worldwide acceptance of both services within the community of glycoscienists. BCSDB is available at http://www.glyco.ac.ru/bcsdb/ and the GLYCOSCIENCES.de portal at http://www.glycosciences.de/

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors


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