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Nucleic Acids Research Advance Access originally published online on November 29, 2006
Nucleic Acids Research 2007 35(Database issue):D557-D560; doi:10.1093/nar/gkl961
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Nucleic Acids Research, 2007, Vol. 35, Database issue D557-D560
© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles

DOMINO: a database of domain–peptide interactions

Arnaud Ceol, Andrew Chatr-aryamontri, Elena Santonico, Roberto Sacco, Luisa Castagnoli and Gianni Cesareni*

Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy

*To whom correspondence should be addressed. Tel: +39 0672594315; Fax: +39 062023500; Email: Cesareni{at}uniroma2.it

Received August 8, 2006. Revised October 25, 2006. Accepted October 25, 2006.

Many protein interactions are mediated by small protein modules binding to short linear peptides. DOMINO (http://mint.bio.uniroma2.it/domino/) is an open-access database comprising more than 3900 annotated experiments describing interactions mediated by protein-interaction domains. DOMINO can be searched with a versatile search tool and the interaction networks can be visualized with a convenient graphic display applet that explicitly identifies the domains/sites involved in the interactions.

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors


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