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Nucleic Acids Research Advance Access originally published online on December 1, 2006
Nucleic Acids Research 2007 35(Database issue):D561-D565; doi:10.1093/nar/gkl958
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Nucleic Acids Research, 2007, Vol. 35, Database issue D561-D565
© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles

IntAct—open source resource for molecular interaction data

S. Kerrien*, Y. Alam-Faruque, B. Aranda, I. Bancarz, A. Bridge1, C. Derow, E. Dimmer, M. Feuermann1, A. Friedrichsen, R. Huntley, C. Kohler, J. Khadake, C. Leroy, A. Liban, C. Lieftink, L. Montecchi-Palazzi, S. Orchard, J. Risse, K. Robbe, B. Roechert1, D. Thorneycroft, Y. Zhang, R. Apweiler and H. Hermjakob

EMBL Outstation—European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus Hinxton, Cambridge, CB10 1SD, UK 1 Swiss Institute of Bioinformatics Geneva, Switzerland

*To whom correspondence should be addressed. Tel: +44 0 1223 494 671; Fax: +44 0 1223 494 468; Email: skerrien{at}ebi.ac.uk

Received September 15, 2006. Revised October 23, 2006. Accepted October 24, 2006.

IntAct is an open source database and software suite for modeling, storing and analyzing molecular interaction data. The data available in the database originates entirely from published literature and is manually annotated by expert biologists to a high level of detail, including experimental methods, conditions and interacting domains. The database features over 126 000 binary interactions extracted from over 2100 scientific publications and makes extensive use of controlled vocabularies. The web site provides tools allowing users to search, visualize and download data from the repository. IntAct supports and encourages local installations as well as direct data submission and curation collaborations. IntAct source code and data are freely available from http://www.ebi.ac.uk/intact.


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