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Nucleic Acids Research Advance Access originally published online on November 11, 2006
Nucleic Acids Research 2007 35(Database issue):D800-D804; doi:10.1093/nar/gkl856
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Nucleic Acids Research, 2007, Vol. 35, Database issue D800-D804
© 2006 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles

probeBase—an online resource for rRNA-targeted oligonucleotide probes: new features 2007

Alexander Loy, Frank Maixner, Michael Wagner and Matthias Horn*

Department für Mikrobielle Ökologie, Universität Wien Althanstrasse 14, A-1090 Wien, Austria

*To whom correspondence should be addressed: Tel: +43 1 4277 54393; Fax: +43 1 4277 54389; Email: horn{at}microbial-ecology.net

Received September 13, 2006. Revised October 10, 2006. Accepted October 10, 2006.

probeBase is a curated database of annotated rRNA-targeted oligonucleotide probes and supporting information. Rapid access to probe, microarray and reference data is achieved by powerful search tools and via different lists that are based on selected categories such as functional or taxonomic properties of the target organism(s) or the hybridization format (fluorescence in situ hybridization or microarray) in which the probes were applied. Additional information on probe coverage and specificity is available through direct submissions of probe sequences from probeBase to RDP-II and Greengenes, two major rRNA sequence databases. A freely editable user comments field for each probe entry allows any user to add, modify or remove information or to report errors in real-time. probeBase entries increased from 700 to more than 1200 during the past three years. Several options for submission of single probes or entire probe sets, even prior to publication of newly developed probes, should further contribute to keeping probeBase an up-to-date and useful resource. probeBase is freely accessible at http://www.microbial-ecology.net/probebase. Email correspondence can be addressed to probebase{at}microbial-ecology.net.


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