Nucleic Acids Research Advance Access originally published online on November 19, 2007
Nucleic Acids Research 2008 36(Database issue):D512-D516; doi:10.1093/nar/gkm962
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Nucleic Acids Research, 2008, Vol. 36, Database issue D512-D516
© 2007 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]
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The hepatitis C sequence database in Los Alamos
HCV database, Los Alamos National Laboratory, Los Alamos, NM, USA
*To whom correspondence should be addressed. Tel: +1 505 665 6463; Fax: +505 665 3493; Email: kuiken{at}lanl.gov
Received September 25, 2007. Revised October 16, 2007. Accepted October 17, 2007.
The hepatitis C virus (HCV) is a significant public health threat worldwide. The virus is highly variable and evolves rapidly, making it an elusive target for the immune system and for vaccine and drug design. Presently, 
50 000 HCV sequences have been published. A central website that provides annotated sequences and analysis tools will be helpful to HCV scientists worldwide. The HCV sequence database collects and annotates sequence data, and provides them to the public via a website that contains a user-friendly search interface and a large number of sequence analysis tools, following the model of the highly regarded and widely used Los Alamos HIV database. The HCV website can be accessed via http://hcv.lanl.gov and http://hcv-db.org.
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