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Nucleic Acids Research Advance Access originally published online on October 26, 2007
Nucleic Acids Research 2008 36(Database issue):D700-D706; doi:10.1093/nar/gkm907
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Nucleic Acids Research, 2008, Vol. 36, Database issue D700-D706
© 2007 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]

Articles

The Molecule Pages database

Brian Saunders1, Stephen Lyon1, Matthew Day2, Brenda Riley2, Emily Chenette3 and Shankar Subramaniam1,4,*

1San Diego Supercomputer Center San Diego, La Jolla, CA 92093, 2Nature Publishing Group, 25 First Street, Cambridge, MA 02141, USA, 3Nature Publishing Group, The Macmillan Building, 4 Crinan Street, London N1 9XW, UK and 4Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA

*To whom correspondence should be addressed. Tel: +1 858 822 0986; Fax: +1 858 822 3752; Email: shankar{at}sdsc.edu

Received August 31, 2007. Revised October 4, 2007. Accepted October 5, 2007.

The UCSD-Nature Signaling Gateway Molecule Pages (http://www.signaling-gateway.org/molecule) provides essential information on more than 3800 mammalian proteins involved in cellular signaling. The Molecule Pages contain expert-authored and peer-reviewed information based on the published literature, complemented by regularly updated information derived from public data source references and sequence analysis. The expert-authored data includes both a full-text review about the molecule, with citations, and highly structured data for bioinformatics interrogation, including information on protein interactions and states, transitions between states and protein function. The expert-authored pages are anonymously peer reviewed by the Nature Publishing Group. The Molecule Pages data is present in an object-relational database format and is freely accessible to the authors, the reviewers and the public from a web browser that serves as a presentation layer. The Molecule Pages are supported by several applications that along with the database and the interfaces form a multi-tier architecture. The Molecule Pages and the Signaling Gateway are routinely accessed by a very large research community.


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