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Nucleic Acids Research 2009 37(Database issue):D1025-D1028; doi:10.1093/nar/gkn966
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Nucleic Acids Research, 2009, Vol. 37, Database issue D1025-D1028
© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]

Articles

The YH database: the first Asian diploid genome database

Guoqing Li1, Lijia Ma1,2, Chao Song1, Zhentao Yang1, Xiulan Wang1, Hui Huang1, Yingrui Li1, Ruiqiang Li1,3, Xiuqing Zhang1, Huanming Yang1, Jian Wang1,* and Jun Wang1,3,*

1Beijing Genomics Institute at Shenzhen 518083, 2The Graduate University of Chinese Academy of Sciences, Beijing, 100062, China and 3Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, DK-5230, Denmark

*To whom correspondence should be addressed. Tel: +86 755 25273796; Fax: +86 755 25273796; Email: wangjian{at}genomics.org.cn

Correspondence may also be addressed to Jun Wang. Tel: +86 755 25273796; Fax: +86 755 25273796; Email: wangj{at}genomics.org.cn

Received August 12, 2008. Revised November 14, 2008. Accepted November 14, 2008.

The YH database is a server that allows the user to easily browse and download data from the first Asian diploid genome. The aim of this platform is to facilitate the study of this Asian genome and to enable improved organization and presentation large-scale personal genome data. Powered by GBrowse, we illustrate here the genome sequences, SNPs, and sequencing reads in the MapView. The relationships between phenotype and genotype can be searched by location, dbSNP ID, HGMD ID, gene symbol and disease name. A BLAST web service is also provided for the purpose of aligning query sequence against YH genome consensus. The YH database is currently one of the three personal genome database, organizing the original data and analysis results in a user-friendly interface, which is an endeavor to achieve fundamental goals for establishing personal medicine. The database is available at http://yh.genomics.org.cn.

The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors.


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