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Nucleic Acids Research Advance Access originally published online on November 14, 2008
Nucleic Acids Research 2009 37(Database issue):D365-D368; doi:10.1093/nar/gkn790
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Nucleic Acids Research, 2009, Vol. 37, Database issue D365-D368
© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]

Articles

The protein structure initiative structural genomics knowledgebase

Helen M. Berman1,*, John D. Westbrook1, Margaret J. Gabanyi1, Wendy Tao1, Raship Shah1, Andrei Kouranov1, Torsten Schwede2, Konstantin Arnold2, Florian Kiefer2, Lorenza Bordoli2, Jürgen Kopp2,3, Michael Podvinec2, Paul D. Adams4, Lester G. Carter4, Wladek Minor5, Rajesh Nair6 and Joshua La Baer7

1Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, 2Swiss Institute of Bioinfomatics & Biozentrum, University of Basel, CH-4056 Basel, Switzerland, 3Biochemie-Zentrum, Heidelberg University, D-69120 Heidelberg, Germany, 4Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, 5Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908-0736, 6Department of Biochemistry & Molecular Biophysics, Columbia University, New York, NY 10027 and 7Harvard Institute of Proteomics & Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115

*To whom correspondence should be addressed. Tel: +1-732-445-0103; Fax: +1-732-445-4320; Email: berman{at}rcsb.rutgers.edu

Received September 16, 2008. Accepted October 8, 2008.

The Protein Structure Initiative Structural Genomics Knowledgebase (PSI SGKB, http://kb.psi-structuralgenomics.org) has been created to turn the products of the PSI structural genomics effort into knowledge that can be used by the biological research community to understand living systems and disease. This resource provides central access to structures in the Protein Data Bank (PDB), along with functional annotations, associated homology models, worldwide protein target tracking information, available protocols and the potential to obtain DNA materials for many of the targets. It also offers the ability to search all of the structural and methodological publications and the innovative technologies that were catalyzed by the PSI's high-throughput research efforts. In collaboration with the Nature Publishing Group, the PSI SGKB provides a research library, editorials about new research advances, news and an events calendar to present a broader view of structural biology and structural genomics. By making these resources freely available, the PSI SGKB serves as a bridge to connect the structural biology and the greater biomedical communities.


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