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Nucleic Acids Research Advance Access originally published online on November 16, 2008
Nucleic Acids Research 2009 37(Database issue):D550-D554; doi:10.1093/nar/gkn859
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Nucleic Acids Research, 2009, Vol. 37, Database issue D550-D554
© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]

Articles

Génolevures: protein families and synteny among complete hemiascomycetous yeast proteomes and genomes

David J. Sherman1,2,*, Tiphaine Martin1, Macha Nikolski1, Cyril Cayla1, Jean-Luc Souciet3, Pascal Durrens1,{dagger} for the Génolevures Consortium

1LaBRI, Laboratoire Bordelais de Recherche en Informatique, UMR CNRS 5800, 2INRIA, Institut National de Recherche en Informatique, Centre de Recherche Bordeaux Sud-Ouest, 351 Cours de la Libération, 33405 Talence cedex and 3Université Louis Pasteur, CNRS, UMR 7156, GDR 2354, Institut de Botanique, 28 rue Goethe, F-67000 Strasbourg, France

*To whom correspondence should be addressed. Tel: +33 540 00 6922; Fax: +33 540 00 6669; Email: david.sherman{at}labri.fr

Received September 15, 2008. Revised October 15, 2008. Accepted October 16, 2008.

The Génolevures online database (http://cbi.labri.fr/Genolevures/ and http://genolevures.org/) provides exploratory tools and curated data sets relative to nine complete and seven partial genome sequences determined and manually annotated by the Génolevures Consortium, to facilitate comparative genomic studies of Hemiascomycete yeasts. The 2008 update to the Génolevures database provides four new genomes in complete (subtelomere to subtelomere) chromosome sequences, 50 000 protein-coding and tRNA genes, and in silico analyses for each gene element. A key element is a novel classification of conserved multi-species protein families and their use in detecting synteny, gene fusions and other aspects of genome remodeling in evolution. Our purpose is to release high-quality curated data from complete genomes, with a focus on the relations between genes, genomes and proteins.

{dagger}The members of the Génolevures Consortium are listed in the Appendix.


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