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Nucleic Acids Research Advance Access originally published online on November 3, 2008
Nucleic Acids Research 2009 37(Database issue):D712-D719; doi:10.1093/nar/gkn886
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Nucleic Acids Research, 2009, Vol. 37, Database issue D712-D719
© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

This article appears in the following Nucleic Acids Research issue: Database issue [View the issue table of contents]

Articles

The Mouse Genome Database genotypes::phenotypes

Judith A. Blake*, Carol J. Bult, Janan T. Eppig, James A. Kadin, Joel E. Richardson{dagger} and the Mouse Genome Database Group

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA

*To whom correspondence should be addressed. Tel: +1 207 288 6248; Fax: +1 207 288 6132; Email: jblake{at}informatics.jax.org

Received September 28, 2008. Revised October 19, 2008. Accepted October 20, 2008.

The Mouse Genome Database (MGD, http://www.informatics.jax.org/), integrates genetic, genomic and phenotypic information about the laboratory mouse, a primary animal model for studying human biology and disease. Information in MGD is obtained from diverse sources, including the scientific literature and external databases, such as EntrezGene, UniProt and GenBank. In addition to its extensive collection of phenotypic allele information for mouse genes that is curated from the published biomedical literature and researcher submission, MGI includes a comprehensive representation of mouse genes including sequence, functional (GO) and comparative information. MGD provides a data mining platform that enables the development of translational research hypotheses based on comparative genotype, phenotype and functional analyses. MGI can be accessed by a variety of methods including web-based search forms, a genome sequence browser and downloadable database reports. Programmatic access is available using web services. Recent improvements in MGD described here include the unified mouse gene catalog for NCBI Build 37 of the reference genome assembly, and improved representation of mouse mutants and phenotypes.


{dagger}The Mouse Genome Database Group: M.T. Airey, A. Anagnostopoulos, R.P. Babiuk, R.M. Baldarelli, M.J. Baya, J.S. Beal, S.M. Bello, D.W. Bradt, D.L. Burkart, N.E. Butler, J.W. Campbell, L.E. Corbani, S.L. Cousins, D.J. Dahmen, H. Dene, A.D. Diehl, K.L. Forthofer, K.S. Frazer, D.E. Geel, M.M. Hall, M. Knowlton, J.R. Lewis, I. Lu, L.J. Maltais, M. McAndrews-Hill, S. McClatchy, M.J. McCrossin, T.F. Meehan, D.B. Miers, L.A. Miller, L. Ni, H. Onda, J.E. Ormsby, D.J. Reed, B. Richards-Smith, D.R. Shaw, R. Sinclair, D. Sitnikov, C.L. Smith, P. Szauter, M. Tomczuk, L.L. Washburn, I.T. Witham and Y. Zhu.


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