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Nucleic Acids Research, 1977, Vol. 4, No. 11 4015-4022
© 1977

Articles

Repair of ionizing radiation induced DNA damage In human lymphocytes

M. F. Lavin and Chev Kidson

Department of Biochemistry, University of Queensland Brisbane 4067, Australia

Received September 27, 1977. Phytohemagglutinin stimulated human lymphocytes exhibit a 20 fold increase in DNA repair synthesis.following ionizing radiation damage compared to the level of repair in unstimulated cells. The peak of repair synthesis coincides with that for DNA replication. Stimulated lymphocytes provide a relatively simple assay for ionizing radiation repair defects.


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