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Nucleic Acids Research, 1977, Vol. 4, No. 2 457-460
© 1977

Articles

Terminal deoxynucleotidyl transferase is present in athymic nude mice

J.J. Hutton* and F.J. Bollum

Medical Service, Veterans Administration Hospital Lexington, KY 40507 Department of Biochemistry, University of Kentucky Lexington, KY 40506, USA

*To whom correspondence should be sent

Received December 30, 1976. Terminal deoxynucleotidyl transferase activity is normal in the bone marrow of congenitally athymic nude mice, regardless of whether transferase activity is calculated on the basis of cell number, DNA content, or activity per femur. This suggests that terminal transferase containing cells of marrow do not originate in thymus.


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