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Nucleic Acids Research, 1977, Vol. 4, No. 5 1291-1300
© 1977

Articles

Restriction endonuclease cleavage maps of rat and mouse mitochondrial DNAs

Richard C. Parker1 and Robert M. Watson2

1Division of Biology, California Institute of Technology Pasadena, CA 91125, USA 2Division of Chemistry and Chemical Engineering, California Institute of Technology Pasadena, CA 91125, USA

Received February 28, 1977. Mitochondrial DNA from an Old World mouse, Mus musculus, and from an Old World rat, Rattus norvegicus, contain 19 and 22 distinct sites, respectively, for the 8 restriction encfonucleases, BamHI, EcoRI, HaeII, HhaI, HincII, HindIII, HpaI and PstI. The relative positions of the sites have been mapped by the study of partial and double enzyme digests. Some sites may have been conserved between the mouse and rat mitochondrial genomes.


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