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Nucleic Acids Research, 1978, Vol. 5, No. 6 2095-2098
© 1978


Articles

Repair replication in replicating and non-replicating DNA after irradiation with UV light

H. Slor1 and J. E. Cleaver2

1Department of Human Genetics, Sackler School of Medicine, Tel-Aviv University Tel-Aviv, Israel 2Laboratory of Radiobiology, University of California, San Francisco San Francisco, CA 94143, USA

Received March 8, 1978. Ultraviolet light induces more pyrimidine dimers and more repair replication in DNA that replicates within 2 to 3 hr of irradiation than in DNA that does not replicate during this period. This difference may be due to special conformational changes in DNA and chromatin that might be associated with semiconservative DNA replication.


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