Skip Navigation

This Article
Right arrow Print PDF (1339K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Roe, B. A.
Right arrow Articles by Chen, E. Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Roe, B. A.
Right arrow Articles by Chen, E. Y.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1979, Vol. 6, No. 2 673-688
© 1979

Articles

Comparison of rat liver and Walker 256 carcinosarcoma tRNAs

Bruce A. Roe*, Ann F. Stankiewicz, Helen L. Rizi, Colleen Weisz, Marie N. DiLauro, Debra Pike, Christina Y. Chen and Ellson Y. Chen

Chemistry Department, Kent State University Kent, OH 44242, USA

Received December 8, 1978.

The complete nucleotide sequences of both rat liver and Walker 256 mammary carcinosarcoma tRNAAsn reveal that they are identical except for the nucleotide present in the wobble position of the anticodon loop. The rat liver tRNAAsn contains the Q nucleoside, whereas the tumour tRNAAsn contains an unmodified guanosine. The tRNAs from both tissues also show significant quantitative differences in the chromatographic mobilities for isoaccepting species of tRNAAsp, tRNAAsn, tRNAHis and tRNATyr. In addition, chromatographic shifts upon cyanogen bromide treatment and analyses of the alkaline hydrolysates of these tRNAs demonstrate that those of tumour origin contain significantly less Q and Q* nucleoside than their normal rat liver counterparts.

*Present Address: MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
P. F. Agris
Decoding the genome: a modified view
Nucleic Acids Res., January 9, 2004; 32(1): 223 - 238.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
Katze JR, B Basile, and J. McCloskey
Queuine, a modified base incorporated posttranscriptionally into eukaryotic transfer RNA: wide distribution in nature
Science, April 2, 1982; 216(4541): 55 - 56.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.