Nucleic Acids Research, 1980, Vol. 8, No. 6 1201-1216
© 1980
Articles |
The nucleotide sequence of the ubiquitous repetitive DNA sequence B1 complementary to the most abundant class of mouse fold-back RNA
Institute of Molecular Biology, USSR Academy of Sciences Vavilov street 32, Moscow B-34, USSR
Received February 22, 1980. Three copies of a highly repetitive DNA sequence B1 which is complementary to the most abundant class of mouse fold-back RNA have been cloned in pBR322 plasmid and sequenced by the method of Maxam and Gilbert. All the three have a length of about 130 base pairs and are very similar in their base sequence. The deviation from the average sequence is equal to 4% and the overall mismatch between each two is not higher than 8%, One of the recombinant clones used contained two copies of B1 oriented in the same direction. All of the B1 copies are flanked with sequences which possess nonidentical but very similar structure. They consist of a number of AmCn blocks (where m varies from 2 to 8 and n equals 1–2). These peculiar sequences in all cases are separated from B1 by non-homologous DNA stretches of 2–8 residues. In one case, a long polypurine stretch is located next to such a block. It consists of 74 residues most of which represent a reiteration of the basic sequence AAAAG. We have found two regions within the B1 sequence which are homologous to the intron-exon junctions, especially to those present in the large intron of the mouse ß-globin gene. It may indicate the involvement of the B1 sequence in pre-mRNA splicing.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A. J. Gentles, O. Kohany, and J. Jurka Evolutionary Diversity and Potential Recombinogenic Role of Integration Targets of Non-LTR Retrotransposons Mol. Biol. Evol., October 1, 2005; 22(10): 1983 - 1991. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. S. Lobachev, B. M. Shor, H. T. Tran, W. Taylor, J. D. Keen, M. A. Resnick, and D. A. Gordenin Factors Affecting Inverted Repeat Stimulation of Recombination and Deletion in Saccharomyces cerevisiae Genetics, April 1, 1998; 148(4): 1507 - 1524. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Puech, A. Dupressoir, M.-P. Loireau, M.-G. Mattei, and T. Heidmann Characterization of Two Age-induced Intracisternal A-particle-related Transcripts in the Mouse Liver. TRANSCRIPTIONAL READ-THROUGH INTO AN OPEN READING FRAME WITH SIMILARITIES TO THE YEAST CCR4 TRANSCRIPTION FACTOR J. Biol. Chem., February 28, 1997; 272(9): 5995 - 6003. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J L Rothstein, D Johnson, J A DeLoia, J Skowronski, D Solter, and B Knowles Gene expression during preimplantation mouse development. Genes & Dev., July 1, 1992; 6(7): 1190 - 1201. [Abstract] [PDF]
|
|
|
|
 |
|
 C. Schmid and W. Jelinek The Alu family of dispersed repetitive sequences Science, June 4, 1982; 216(4550): 1065 - 1070. [Abstract] [PDF]
|
|
|
|
|
|
K. Moore, B. Sher, Y. Sun, K. Eakle, and L Hood DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen Science, February 5, 1982; 215(4533): 679 - 682. [Abstract] [PDF]
|
|
|
|
|
|
Y. Ueda and G. Chaudhuri Differential Expression of B1-containing Transcripts in Leishmania-exposed Macrophages J. Biol. Chem., June 16, 2000; 275(25): 19428 - 19432. [Abstract] [Full Text] [PDF]
|
|