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Nucleic Acids Research, 1981, Vol. 9, No. 5 1045-1052
© 1981

MOLECULAR BIOLOGY

Human fibroblast interferon gene lacks introns

Richard M. Lawn, John Adelman, Arthur E. Franke, Catherine M. Houck, Mitchell Gross, Richard Najarian and David V. Goeddel

Department of Molecular Biology, Genentech, Inc. 460 Pt. San Bruno Blvd., South San Francisco, CA 94080, USA

Received January 30, 1981. A recombinant {lambda} bacteriophage isolated from a human genome library contains the gene for fibroblast interferon (IFN-ß1). The DNA sequence of this gene is identical to the sequence of its mRNA and is devoid of introns.


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