Skip Navigation

This Article
Right arrow Print PDF (668K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Wilkes, P.R.
Right arrow Articles by Birnie, G.D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wilkes, P.R.
Right arrow Articles by Birnie, G.D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1981, Vol. 9, No. 8 2021-2035
© 1981

MOLECULAR BIOLOGY

The appearance of new polyadenylated nuclear RNA sequences during rat-liver regeneration

P.R. Wilkes and G.D. Birnie

The Beatson Institute for Cancer Research Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK

Received January 26, 1981. Polyadenylated RNA populations from normal and 16-hour regenerating rat-liver nuclei were compared by heterologous hybridisation reactions with cDNA and unique DNA probes. Whereas unique DNA hybridisations did not show differences between the RNA populations, comparisons by cDNA hybridisation showed that about 10–15% by weight of polyadenylated sequences present in the nuclei of 16-hour regenerating rat livers were not found in the poly-adenylated nuclear RNA of normal rat livers. These regenerating-sepecific nuclear cDNA sequences were isolated and characterised; the experiments showed that the complexity of the new sequences was 1–2 x 107 nucleotides (equivalent to 5,000–10,000 RNA sequences of 2,000 nucleotides in length) and that they were probably not potential messenger RNA sequences.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.