Skip Navigation



Nucleic Acids Research Advance Access published online on November 20, 2008
Nucleic Acids Research, doi:10.1093/nar/gkn862
This Article
Right arrow Full Text Freely available
Right arrow Print PDF (81K) Freely available
Right arrow Screen PDF (90K) Freely available
Right arrowOA All Versions of this Article:
37/suppl_1/D274    most recent
gkn862v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Saier, M. H.
Right arrow Articles by Elkan, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Saier, M. H., Jr
Right arrow Articles by Elkan, C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

The Transporter Classification Database: recent advances

Milton H. Saier, Jr1,*, Ming Ren Yen1, Keith Noto2, Dorjee G. Tamang1 and Charles Elkan2

1Division of Biological Sciences and 2Department of Computer Science and Engineering, University of California at San Diego, La Jolla, CA 92093-0116, USA

*To whom correspondence should be addressed. Tel: +1 858 534 4084; Fax: +1 858 534 7108; Email: msaier{at}ucsd.edu

Received September 16, 2008. Revised October 14, 2008. Accepted October 16, 2008.

The Transporter Classification Database (TCDB), freely accessible at http://www.tcdb.org, is a relational database containing sequence, structural, functional and evolutionary information about transport systems from a variety of living organisms, based on the International Union of Biochemistry and Molecular Biology-approved transporter classification (TC) system. It is a curated repository for factual information compiled largely from published references. It uses a functional/phylogenetic system of classification, and currently encompasses about 5000 representative transporters and putative transporters in more than 500 families. We here describe novel software designed to support and extend the usefulness of TCDB. Our recent efforts render it more user friendly, incorporate machine learning to input novel data in a semiautomatic fashion, and allow analyses that are more accurate and less time consuming. The availability of these tools has resulted in recognition of distant phylogenetic relationships and tremendous expansion of the information available to TCDB users.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Antimicrob. Agents Chemother.Home page
V. Dhote, A. L. Starosta, D. N. Wilson, and K. A. Reynolds
The Final Step of Hygromycin A Biosynthesis, Oxidation of C-5''-Dihydrohygromycin A, Is Linked to a Putative Proton Gradient-Dependent Efflux
Antimicrob. Agents Chemother., December 1, 2009; 53(12): 5163 - 5172.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. Marsico, K. Scheubert, A. Tuukkanen, A. Henschel, C. Winter, R. Winnenburg, and M. Schroeder
MeMotif: a database of linear motifs in {alpha}-helical transmembrane proteins
Nucleic Acids Res., November 12, 2009; (2009) gkp1042v1.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.