Skip Navigation



Nucleic Acids Research Advance Access published online on September 25, 2009
Nucleic Acids Research, doi:10.1093/nar/gkp788
This Article
Right arrow Full Text Freely available
Right arrow Print PDF (1447K) Freely available
Right arrow Screen PDF (367K) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Bekaert, M.
Right arrow Articles by Baranov, P. V.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bekaert, M.
Right arrow Articles by Baranov, P. V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author(s) 2009. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

Recode-2: new design, new search tools, and many more genes

Michaël Bekaert1, Andrew E. Firth2, Yan Zhang3, Vadim N. Gladyshev3, John F. Atkins2,4 and Pavel V. Baranov5,*

1School of Biology and Environmental Science, University College Dublin, 2BioSciences Institute, University College Cork, Ireland, 3Division of Genetics, Department of Medicine, Brigham & Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA, 4Human Genetics Department, University of Utah, UT 84112 USA and 5Biochemistry Department, University College Cork, Ireland

*To whom correspondence should be addressed. Tel: +353 (0) 21 4904212; Fax: +353 (0) 21 4904259; Email: p.baranov{at}ucc.ie

Received August 15, 2009. Accepted September 4, 2009.

‘Recoding’ is a term used to describe non-standard read-out of the genetic code, and encompasses such phenomena as programmed ribosomal frameshifting, stop codon readthrough, selenocysteine insertion and translational bypassing. Although only a small proportion of genes utilize recoding in protein synthesis, accurate annotation of ‘recoded’ genes lags far behind annotation of ‘standard’ genes. In order to address this issue, provide a service to researchers in the field, and offer training data for developers of gene-annotation software, we have gathered together known cases of recoding within the Recode database. Recode-2 is an improved and updated version of the database. It provides access to detailed information on genes known to utilize translational recoding and allows complex search queries, browsing of recoding data and enhanced visualization of annotated sequence elements. At present, the Recode-2 database stores information on approximately 1500 genes that are known to utilize recoding in their expression—a factor of approximately three increase over the previous version of the database. Recode-2 is available at http://recode.ucc.ie


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.