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Nucleic Acids Research Advance Access published online on October 27, 2009
Nucleic Acids Research, doi:10.1093/nar/gkp880
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© The Author(s) 2009. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

The Mouse Genome Database: enhancements and updates

Carol J. Bult*, James A. Kadin, Joel E. Richardson, Judith A. Blake, Janan T Eppig and the Mouse Genome Database Group{dagger}

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 USA

*To whom correspondence should be addressed. Tel: +1 207 288 6248; Fax: +1 207 288 6132; Email: carol.bult{at}jax.org

Received September 15, 2009. Accepted October 1, 2009.

The Mouse Genome Database (MGD) is a major component of the Mouse Genome Informatics (MGI, http://www.informatics.jax.org/) database resource and serves as the primary community model organism database for the laboratory mouse. MGD is the authoritative source for mouse gene, allele and strain nomenclature and for phenotype and functional annotations of mouse genes. MGD contains comprehensive data and information related to mouse genes and their functions, standardized descriptions of mouse phenotypes, extensive integration of DNA and protein sequence data, normalized representation of genome and genome variant information including comparative data on mammalian genes. Data for MGD are obtained from diverse sources including manual curation of the biomedical literature and direct contributions from individual investigator’s laboratories and major informatics resource centers, such as Ensembl, UniProt and NCBI. MGD collaborates with the bioinformatics community on the development and use of biomedical ontologies such as the Gene Ontology and the Mammalian Phenotype Ontology. Recent improvements in MGD described here includes integration of mouse gene trap allele and sequence data, integration of gene targeting information from the International Knockout Mouse Consortium, deployment of an MGI Biomart, and enhancements to our batch query capability for customized data access and retrieval.

{dagger}The Mouse Genome Database Group: M. T. Airey, A. Anagnostopoulos, R. Babiuk, R. M. Baldarelli, M. Baya, J. S. Beal, S. M. Bello, D. W. Bradt, D. L. Burkart, N. E. Butler, J. Campbell, L. E. Corbani, S. L. Cousins, D. J. Dahmen, H. Dene, A. D. Diehl, M. E. Dolan, K. L. Forthofer, K. S. Frazer, P. Frost, D. E. Geel, M. Hall, M. Knowlton, J. R. Lewis, L. J. Maltais, M. McAndrews-Hill, S. McClatchy, M. J. McCrossin, J. Mason, T. F. Meehan, D. B. Miers, L. A. Miller, L. Ni, H. Onda, J. E. Ormsby, D. J. Reed, B. Richards-Smith, D. R. Shaw, R. Sinclair, D. Sitnikov, C. L. Smith, P. Szauter, M. Tomczuk, L. L. Washburn, I. T. Witham, Y. Zhu.


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