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Nucleic Acids Research Advance Access published online on November 13, 2009

Nucleic Acids Research, doi:10.1093/nar/gkp941
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© The Author(s) 2009. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Database Issue

EuPathDB: a portal to eukaryotic pathogen databases

Cristina Aurrecoechea1, John Brestelli2,3, Brian P. Brunk2,4, Steve Fischer2,3, Bindu Gajria2,4, Xin Gao2,4, Alan Gingle5, Greg Grant2,3, Omar S. Harb2,4,*, Mark Heiges1, Frank Innamorato2,3, John Iodice2,3, Jessica C. Kissinger1,6, Eileen T. Kraemer7, Wei Li2,4, John A. Miller7, Vishal Nayak2,3, Cary Pennington1, Deborah F. Pinney2,3, David S. Roos4, Chris Ross1, Ganesh Srinivasamoorthy1, Christian J. Stoeckert, Jr2,3, Ryan Thibodeau1, Charles Treatman2,4 and Haiming Wang1

1Center for Tropical & Emerging Global Diseases, University of Georgia, Athens, GA 30602, 2Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA 19104, 3Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, 4Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, 5Center for Applied Genetic Technologies, University of Georgia, Athens, GA 30602, 6Department of Genetics, University of Georgia, Athens, GA 30602 and 7Department of Computer Science, University of Georgia, Athens, GA 30602, USA

*To whom correspondence should be addressed. Tel: +1 215 746 7019; Fax: +1 215 573 3111; Email: oharb{at}pcbi.upenn.edu

Correspondence may also be addressed to Brian P. Brunk. Tel: +1 215 573 3118; Fax: +1 215 573 3111; Email: brunkb{at}pcbi.upenn.edu

Correspondence may also be addressed to Jessica C. Kissinger. Tel: +1 706 542 6562; Fax: +1 706 542 3582; Email: jkissing{at}uga.edu

Correspondence may also be addressed to David S. Roos. Tel: +1 215 898 2118; Fax: +1 215 746 6697; Email: droos{at}sas.upenn.edu

Correspondence may also be addressed to Christian J. Stoeckert. Tel: +1 215 573 4409; Fax: +1 215 573 3111; Email: stoeckrt{at}pcbi.upenn.edu

Received September 16, 2009. Accepted October 10, 2009.

EuPathDB (http://EuPathDB.org; formerly ApiDB) is an integrated database covering the eukaryotic pathogens of the genera Cryptosporidium, Giardia, Leishmania, Neospora, Plasmodium, Toxoplasma, Trichomonas and Trypanosoma. While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the EuPathDB portal offers an entry point to all these resources, and the opportunity to leverage orthology for searches across genera. The most recent release of EuPathDB includes updates and changes affecting data content, infrastructure and the user interface, improving data access and enhancing the user experience. EuPathDB currently supports more than 80 searches and the recently-implemented ‘search strategy’ system enables users to construct complex multi-step searches via a graphical interface. Search results are dynamically displayed as the strategy is constructed or modified, and can be downloaded, saved, revised, or shared with other database users.


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