Nucleic Acids Research Advance Access published online on November 13, 2009
Nucleic Acids Research, doi:10.1093/nar/gkp941
Database Issue |
EuPathDB: a portal to eukaryotic pathogen databases
1Center for Tropical & Emerging Global Diseases, University of Georgia, Athens, GA 30602, 2Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, PA 19104, 3Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, 4Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, 5Center for Applied Genetic Technologies, University of Georgia, Athens, GA 30602, 6Department of Genetics, University of Georgia, Athens, GA 30602 and 7Department of Computer Science, University of Georgia, Athens, GA 30602, USA
*To whom correspondence should be addressed. Tel: +1 215 746 7019; Fax: +1 215 573 3111; Email: oharb{at}pcbi.upenn.edu
Correspondence may also be addressed to Brian P. Brunk. Tel: +1 215 573 3118; Fax: +1 215 573 3111; Email: brunkb{at}pcbi.upenn.edu
Correspondence may also be addressed to Jessica C. Kissinger. Tel: +1 706 542 6562; Fax: +1 706 542 3582; Email: jkissing{at}uga.edu
Correspondence may also be addressed to David S. Roos. Tel: +1 215 898 2118; Fax: +1 215 746 6697; Email: droos{at}sas.upenn.edu
Correspondence may also be addressed to Christian J. Stoeckert. Tel: +1 215 573 4409; Fax: +1 215 573 3111; Email: stoeckrt{at}pcbi.upenn.edu
Received September 16, 2009. Accepted October 10, 2009.
EuPathDB (http://EuPathDB.org; formerly ApiDB) is an integrated database covering the eukaryotic pathogens of the genera Cryptosporidium, Giardia, Leishmania, Neospora, Plasmodium, Toxoplasma, Trichomonas and Trypanosoma. While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the EuPathDB portal offers an entry point to all these resources, and the opportunity to leverage orthology for searches across genera. The most recent release of EuPathDB includes updates and changes affecting data content, infrastructure and the user interface, improving data access and enhancing the user experience. EuPathDB currently supports more than 80 searches and the recently-implemented search strategy system enables users to construct complex multi-step searches via a graphical interface. Search results are dynamically displayed as the strategy is constructed or modified, and can be downloaded, saved, revised, or shared with other database users.