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Nucleic Acids Research Advance Access published online on November 9, 2009
Nucleic Acids Research, doi:10.1093/nar/gkp944
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© The Author(s) 2009. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Database Issue

GWIDD: Genome-wide protein docking database

Petras J. Kundrotas1, Zhengwei Zhu1 and Ilya A. Vakser1,2,*

1Center for Bioinformatics and 2Department of Molecular Biosciences, 2030 Becker Drive, The University of Kansas, Lawrence, KS 66047, USA

*To whom correspondence should be addressed. Tel: +1 785 584 1057; Fax: +1 785 864 5558; Email: vakser{at}ku.edu

Received August 10, 2009. Revised September 27, 2009. Accepted October 12, 2009.

Structural information on interacting proteins is important for understanding life processes at the molecular level. Genome-wide docking database is an integrated resource for structural studies of protein–protein interactions on the genome scale, which combines the available experimental data with models obtained by docking techniques. Current database version (August 2009) contains 25 559 experimental and modeled 3D structures for 771 organisms spanned over the entire universe of life from viruses to humans. Data are organized in a relational database with user-friendly search interface allowing exploration of the database content by a number of parameters. Search results can be interactively previewed and downloaded as PDB-formatted files, along with the information relevant to the specified interactions. The resource is freely available at http://gwidd.bioinformatics.ku.edu.


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