Figure 2. Clickable genomic maps of maxicircle DNAs from four kinetoplastid species.Figure 2 Clickable genomic maps of maxicircle DNAs from four kinetoplastid species. (A) L.tarentolae, (B) T.brucei, (C) C.fasciculata and (D) T.borreli. The molecules are linearized. Genes above the line are in the 5[prime]->3[prime] direction, left to right, and genes below are in the opposite orientation. The number of Us added and deleted are indicated for each editing domain in the L.tarentolae and T.brucei maps (A and B), and the number of sites shown in parenthesis. The locations of maxicircle-encoded gRNAs are indicated and the gRNAs identified by gene and editing block (3[prime]->5[prime] within the editing domain). 12S and 9S, mitochondrial rRNAs; CO, cytochrome oxidase; MURF, maxicircle unidentified reading frame; ND, NADH dehydrogenase; CYb, cytochrome b; A6, ATPase subunit 6; RPS12, ribosomal protein S12; G1-G5 and CR1-CR5, G-rich regions 1-5. Clicking on the gene gives an HTML file of the unedited or edited sequence. Clicking on the gene name gives the map file. Clicking on the species name gives the entire maxicircle sequence from GenBank.