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Figure 1. Mutated and wild-type (wt) versions of the siRNA hTF167i. The sequence of the sense strand of wild-type siRNA corresponds to position 167–187 in hTF (Acc.No. M16553). Single (s1, s2, s3, s4, s7, s10, s11, s13, s16) and double (ds7/10, ds10/11, ds10/13, ds10/16) mutants are all named according to the position of the mutation, counted from the 5' end of the sense strand. All mutations (in bold) are GC inversions relative to the wild-type.
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