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Corrigendum for Rozners and Moulder, Nucl. Acids Res. 32 (1) 248-254.
Nucleic Acids Research 2004 32(20):6153; doi:10.1093/nar/gkh955
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Published online 24 November 2004

Nucleic Acids Research, Vol. 32 No. 20 © Oxford University Press 2004; all rights reserved

Corrigendum

Hydration of short DNA, RNA, and 2'-OMe oligonucleotides determined by osmotic stressing

Eriks Rozners and Janelle Moulder

The authors would like to apologize for an error that appears in Table 2. Because of an inadvertent error in the spread sheet calculations, the number of water molecules for d(CG)3 (3a) was underestimated. The correct Table 2 should be:


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  		Table 2. Values of {Delta}nW (per base pair)

 
Thus, in DNA the GC base pairs are hydrated to a similar or slightly higher extent than in RNA. The {Delta}nW for DNA duplexes is 2–5 and appears to be more sequence dependant than for RNA ({Delta}nW = 3–4) or 2'-OMe ({Delta}nW = 2–3) duplexes. Therefore, until more osmotic stressing data on different sequences are accumulated, comparisons of DNA and RNA hydration are perhaps best done with some skepticism.


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This Article
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