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Figure 2. Sequence walkers to test E. coli (A and B) and B. subtilis (C and D) Fur models. (A and B) The three E. coli Fur models (M12, M9 and M6) were tested with two E. coli Fur binding sites, fepB and entS (55). Sequence walkers of each model (green, M12; red, M9; blue, M6) are shown for each site. (C and D) Two B. subtilis Fur models (M9 and M6) were tested with two B. subtilis Fur binding sites, feuA and dhbA (40). Gray bars indicate natural sequence, surrounded by synthetic DNA. Different colored rectangles indicate different Fur models (by hue: green, M12; red, M9; blue, M6) and their strengths (by saturation) (30). Only major walkers are shown in these figures, for a full list of walkers (Ri>0 bits) please see Supplementary Figures S3, S5 and S7.
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