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Supplementary Table 1. NAR Molecular Biology Database Collection: 2008 updatea

Nob Database name Full name and/or description URL
1. Nucleotide Sequence Databases
1.1. International Nucleotide Sequence Database Collaboration
1 DDBJ - DNA Data Bank of Japan All known nucleotide and protein sequences http://www.ddbj.nig.ac.jp
2 EMBL Nucleotide Sequence Database All known nucleotide and protein sequences http://www.ebi.ac.uk/embl.html
3 GenBank® All known nucleotide and protein sequences http://www.ncbi.nlm.nih.gov/Entrez
1.2. Coding and coding DNA: genes, motifs and regulatory sites
403 ACLAME A classification of genetic mobile elements http://aclame.ulb.ac.be/
337 CORG Comparative Regulatory Genomics: conserved non-coding blocks in vertebrate species http://corg.molgen.mpg.de
30 CUTG Codon Usage Tabulated from GenBank http://www.kazusa.or.jp/codon/
1157 ECRbase Database of Evolutionary Conserved Regions, promoters, and transcription factor binding sites http://ecrbase.dcode.org/
668 Entrez Gene Gene-centered information at NCBI http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene
669 FESD Functional Element SNPs Database: SNPs located within promoters, UTRs, etc., of human genes http://sysbio.kribb.re.kr/FESD/  
468 FREP Functional Repeats in mouse cDNAs http://facts.gsc.riken.go.jp/FREP/
480 Genetic Codes Genetic codes in various organisms and organelles http://www.ncbi.nlm.nih.gov/Taxonomy/Utils/wprintgc.cgi?mode=c
1079 GISSD Group I Intron Sequence and Structure Database http://www.rna.whu.edu.cn/gissd
1083 GyDB Gypsy database of mobile genetic elements http://gydb.uv.es/gydb/intro.htm
825 HumHot Human meiotic recombination hot spots http://www.jncasr.ac.in/humhot/
932 InSatDb Sequences and properties of insect microsatellites http://www.cdfd.org.in/insatdb
832 ISfinder Insertion sequences from bacteria and archaea http://www-is.biotoul.fr
512 Islander Pathogenicity islands and prophages in bacterial genomes http://www.indiana.edu/~islander
697 L1Base Functional annotation and prediction of LINE-1 elements http://line1.molgen.mpg.de
19 MethDB DNA methylation data, patterns and profiles http://www.methdb.de
343 MICdb Prokaryotic microsatellites http://210.212.212.7/MIC/index.html
707 NPRD Nucleosome Positioning Region Database http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?page+ LibInfo+-id+2Xnp11RCiPU+-lib+NUCLEOSOME
931 OriDB DNA Replication Origin Database: Confirmed and predicted sites http://www.oridb.org/
551 PACRAT Archaeal and bacterial intergenic sequence features No longer maintained
608 PANDIT Protein and associated nucleotide domains with inferred trees http://www.ebi.ac.uk/goldman-srv/pandit/
933 Patome Annotated sequences from patents and patent applications http://www.patome.org
958 PolymiRTS Polymorphism in microRNA Target Site http://compbio.utmem.edu/miRSNP/
1007 PseudoGene.org Pseudogenes in eukaryotic and prokaryotic genomes http://www.pseudogene.org/
21 RECODE Genes using programmed translational recoding in their expression http://recode.genetics.utah.edu
391 RefSeq Reference Sequence database: an integrated, non-redundant set of genomic DNA, RNA, and protein sequences http://www.ncbi.nlm.nih.gov/RefSeq/
1019 RetrOryza LTR-retrotransposons in rice http://www.retroryza.org
309 S/MARt DB Nuclear scaffold/matrix attached regions http://smartdb.bioinf.med.uni-goettingen.de/
1013 SNPSTR Microsatellite compound markers in 5 vertebrate genomes http://www3.imperial.ac.uk/theoreticalgenomics/data-software
47 STRBase Short tandem DNA repeats database http://www.cstl.nist.gov/div831/strbase/
929 Synthetic Gene DB Synthetic genes described in peer-reviewed literature http://www.evolvingcode.net/codon/sgdb/index.php
588 TIGR plant repeat DB Classification of repetitive sequences in plant genomes http://www.tigr.org/tdb/e2k1/plant.repeats
1141 TranspoGene Transposed elements influence on the transcriptome of seven vertebrates and invertebrates http://transpogene.tau.ac.il/
1035 TRDB Tandem repeats in genomic DNA http://tandem.bu.edu/cgi-bin/trdb/trdb.exe
1143 UgMicroSatdb UniGene MicroSatellite database: short tandem repeats from various eukaryotic genomes http://ipu.ac.in/usbt/UgMicroSatdb.htm
320 UniVec Vector sequences, adapters, linkers and primers used in DNA cloning, used to check for vector contamination http://www.ncbi.nlm.nih.gov/VecScreen/UniVec.html
252 UTRdb/UTRsite 5'- and 3'-UTRs of eukaryotic mRNAs http://bighost.area.ba.cnr.it/BIG/UTRHome/
1146 UTRome 3'UTRs and their functional elements in C. elegans http://www.utrome.org
302 Vectordb Characterization and classification of nucleic acid vectors http://seq.yeastgenome.org/vectordb/
968 VISTA Enhancer Browser Enhancer elements in the human genome http://enhancer.lbl.gov/
1.3. Gene structure, introns and exons, splice sites
414 ASAP II Comparative analysis of alternative splicing in animal species http://bioinfo.mbi.ucla.edu/ASAP2/
10 ASDB Alternative Splicing Database: protein products and expression patterns of alternatively-spliced genes http://hazelton.lbl.gov/~teplitski/alt/
639 ASHESdb Alternatively Spliced Human genes by Exon Skipping http://sege.ntu.edu.sg/wester/ashes/
28 ASTD Alternative Splicing and Transcript Diversity database http://www.ebi.ac.uk/astd/
920 ATD Alternate transcript diversity database Superseded by ASTD, no. 28
803 ChimerDB Chimeric (fusion) sequences in human, rat and mouse http://genome.ewha.ac.kr/ChimerDB/
450 EASED Extended Alternatively Spliced EST Database http://eased.bioinf.mdc-berlin.de/
667 ECgene Genome annotation for alternative splicing http://genome.ewha.ac.kr/ECgene/
631 EDAS EST-derived alternative splicing database http://www.ig-msk.ru:8005/EDAS/
32 EID Exon-intron database http://www.meduohio.edu/bioinfo/eid/
34 ExInt Exon–intron structure of eukaryotic genes http://sege.ntu.edu.sg/wester/exint/
913 ExtraTRAIN Extragenic regions and transcriptional regulators in bacteria and archaea http://www.era7.com/ExtraTrain/
782 FUGOID Functional genomics of organelle introns database http://web.austin.utexas.edu/fugoid/introndata/main.htm
970 H-DBAS Human database of alternative splicing http://jbirc.jbic.or.jp/h-dbas/
821 Hollywood Exon annotation database http://hollywood.mit.edu
36 HS3D Homo Sapiens Splice Sites Dataset http://www.sci.unisannio.it/docenti/rampone/
238 Intronerator Alternative splicing in C. elegans and C. briggsae http://hgwdev-hiram.cse.ucsc.edu/IntronWS120/
1122 ProSAS Protein Structure and Alternative Splicing: effects of alternative splicing events on protein structure http://services.bio.ifi.lmu.de/ProSAS
46 SpliceDB Canonical and non-canonical mammalian splice sites http://www.softberry.com/berry.phtml?topic=splicedb&group=data&subgroup=spldb
746 SpliceInfo Modes of alternative splicing in human genome http://spliceinfo.mbc.nctu.edu.tw/
580 SpliceNest Visualizing Splicing of Genes from EST Data http://splicenest.molgen.mpg.de/
927 TassDB TAndem Splice Site Database http://helios.informatik.uni-freiburg.de/TassDB/
937 U12DB Database of orthologous U12-type spliceosomal introns http://genome.imim.es/cgi-bin/u12db/u12db.cgi
305 Xpro Eukaryotic protein-encoding DNA sequences, both intron-containing and intron-less genes http://origin.bic.nus.edu.sg/xpro/
342 Yeast Intron Database Ares lab database of splicesomal introns in S. cerevisiae http://www.cse.ucsc.edu/research/compbio/yeast_introns.html
1.4. Transcriptional regulator sites and transcription factors
795 ABS Annotated regulatory binding sites from orthologous promoters http://genome.imim.es/datasets/abs2005/
231 ACTIVITY Functional DNA/RNA site activity http://wwwmgs.bionet.nsc.ru/mgs/systems/activity/
308 ASPD Artificial selected proteins/peptides database http://wwwmgs.bionet.nsc.ru/mgs/gnw/aspd/
805 CisRed Human regulatory DNA sequence motifs http://www.cisred.org/
1058 CMGSDB Computational models for gene silencing in C. elegans https://bioinformatics.cs.vt.edu/cmgs/CMGSDB/
1062 COXPRESdb Coexpressed genes and networks in human and mouse http://coxpresdb.hgc.jp/
1063 CTCF Binding Site DB Experimentally identified and predicted CTCF binding sties http://insulatordb.utmem.edu/
807 DBD Transcription factor prediction database http://www.transcriptionfactor.org/
31 DBTBS Bacillus subtilis promoters and transcription factors http://dbtbs.hgc.jp/
591 DBTSS Database of transcriptional start sites http://dbtss.hgc.jp/
663 DoOP Databases of Orthologous Promoters: chordates and plants http://doop.abc.hu/
106 DPInteract Binding sites for E. coli DNA-binding proteins http://arep.med.harvard.edu/dpinteract/
33 EPD Eukaryotic promoter database http://www.epd.isb-sib.ch/
329 GeneNet Database on gene network components http://wwwmgs.bionet.nsc.ru/mgs/gnw/genenet/
1036 GenomeTraFaC Conserved regulatory elements of human and mouse genes http://genometrafac.cchmc.org
823 HTPSELEX Transcription factor binding site sequences obtained using high-throughput SELEX method http://www.isrec.isb-sib.ch/htpselex/
516 JASPAR PSSMs for transcription factor DNA-binding sites http://jaspar.cgb.ki.se
700 MAPPER Putative transcription factor binding sites in various genomes http://bio.chip.org/mapper
842 MPromDB Mammalian promoter database http://bioinformatics.med.ohio-state.edu/MPromDb
846 ODB Operon database http://odb.kuicr.kyoto-u.ac.jp/
185 ooTFD Object-oriented transcription factors database http://www.ifti.org/ootfd
1107 ORegAnno Open REGulatory ANNOtation database http://www.oreganno.org/
711 Osteo-Promoter DB Genes in osteogenic proliferation and differentiation http://www.opd.tau.ac.il
40 PLACE Plant cis-acting regulatory DNA elements http://www.dna.affrc.go.jp/PLACE/
41 PlantCARE Plant promoters and cis-acting regulatory elements http://bioinformatics.psb.ugent.be/webtools/plantcare/html/
563 PlantProm Plant promoter sequences for RNA polymerase II http://mendel.cs.rhul.ac.uk/mendel.php?topic=plantprom
1117 PlantTFDB Plant Transcription Factor Database http://planttfdb.cbi.pku.edu.cn
1005 PReMod Predicted transcriptional regulatory modules in the human genome http://genomequebec.mcgill.ca/PReMod
566 PRODORIC Prokaryotic database of gene regulation networks http://prodoric.tu-bs.de/
42 PromEC E. coli promoters with experimentally-identified transcriptional start sites http://margalit.huji.ac.il/promec/
1123 ProTISA Translation Initiation Site Annotation in prokaryotic genomes http://mech.ctb.pku.edu.cn/protisa/
116 RegulonDB Transcriptional regulation and operon organization in E.coli http://regulondb.ccg.unam.mx/
45 rSNP Guide SNPs in regulatory gene regions http://wwwmgs.bionet.nsc.ru/mgs/systems/rsnp/
577 SCPD Saccharomyces cerevisiae promoter database http://rulai.cshl.edu/SCPD/
246 SELEXdb Selected DNA/RNA functional site sequences http://wwwmgs.bionet.nsc.ru/mgs/systems/selex/
1015 SwissRegulon database Genome-wide annotations of regulatory sites in the intergenic regions http://www.swissregulon.unibas.ch
227 TESS Transcription element search system http://www.cbil.upenn.edu/tess
904 TiProD Tissue-specific promoter database http://tiprod.cbi.pku.edu.cn:8080/index.html
756 Tractor_DB Transcription factors in gamma-proteobacteria database http://www.tractor.lncc.br
345 TRANSCompel® Transcriptional regulation, composite regulatory elements http://www.gene-regulation.com/pub/ databases.html#transcompel
340 TRANSFAC® Transcription factors, gene regulation, positional weight matrices http://www.gene-regulation.com
1141 TransfactomeDB Nucleotide sequence specificity and condition-specific regulatory activity of trans-acting factors http://bussemakerlab.org/YeastTransfactomeDB/
341 TRANSPATH Signal transduction pathways, vizualization and expression data analysis http://www.biobase.de/pages/products/databases.html
48 Transterm Codon usage, start and stop signals http://guinevere.otago.ac.nz/transterm.html
757 TRED Transcriptional regulatory element database http://rulai.cshl.edu/tred
49 TRRD Transcription regulatory regions of eukaryotic genes http://www.bionet.nsc.ru/trrd/
314 TrSDB Transcription factor database http://bioinf.uab.es/cgi-bin/trsdb/trsdb.pl
792 YEASTRACT Yeast transcriptional regulation http://www.yeastract.com
2. RNA Sequence, Structure and Functions
229 16S and 23S rRNA Mutation Database 16S and 23S ribosomal RNA mutations http://ribosome.fandm.edu
1041 3D rRNA modification maps Locations of modified rRNA nucleotides within the 3D structure of the ribosome http://people.biochem.umass.edu/fournierlab/3dmodmap/
230 5S rRNA Database 5S rRNA sequences http://biobases.ibch.poznan.pl/5SData/
411 Aptamer Database Small RNA/DNA molecules binding nucleic acids, proteins http://aptamer.icmb.utexas.edu
232 ARED AU-rich element-containing mRNAs http://brp.kfshrc.edu.sa/ARED
797 Argonaute Gene regulation by mammalian microRNAs http://argonaute.uni-hd.de
984 dbRES Database of known RNA editing sites http://bioinfo.au.tsinghua.edu.cn/dbRES/
463 European rRNA DB All complete or nearly complete rRNA sequences http://www.psb.ugent.be/rRNA/
1027 fRNAdb Functional RNA Database: noncoding transcripts that affect gene expression http://www.ncrna.org/
878 Greengenes Multiple sequence alignment of prokaryotic 16S rDNA http://greengenes.llnl.gov/16S/
820 GRSDB G-rich sequences database http://bioinformatics.ramapo.edu/GRSDB2/
490 G-tRNA-db Genomic tRNA Database http://lowelab.ucsc.edu/GtRNAdb/
236 Guide RNA Database No longer maintained
76 HIV Sequence DB HIV RNA sequences http://hiv-web.lanl.gov/
689 HuSiDa Human siRNA database http://itb.biologie.hu-berlin.de/~nebulus/sirna/index.htm
237 HyPaLib Hybrid pattern library: structural elements in classes of RNA Not actively maintained
379 IRESdb - the Internal Ribosome Entry Site database http://ifr31w3.toulouse.inserm.fr/IRESdatabase/
831 IRESite Experimentally studied internal ribosome entry sites http://www.iresite.org
838 MeRNA Metal ion binding sites in RNA http://merna.lbl.gov
1097 microRNA.org microRNA target predictions and expression profiles http://www.microrna.org
529 miRBase MicroRNA sequences, names, and predicted targets in animals http://microrna.sanger.ac.uk/sequences/
1098 miRGator microRNA target prediction, functional analysis, and gene expression data http://genome.ewha.ac.kr/miRGator/miRGator.html
994 miRGen Animal microRNAs located in introns, exons, UTRs, pseudogenes and CpG islands http://www.diana.pcbi.upenn.edu/miRGen
895 miRNAMap microRNA precursors and their mapping to targets in vertebrate genomes http://mirnamap.mbc.nctu.edu.tw
378 Mobile group II introns Database for mobile group II introns http://www.fp.ucalgary.ca/group2introns/
840 MODOMICS Database of RNA modification pathways http://genesilico.pl/modomics/
997 NATsDB Natural Antisense Transcripts database http://nats.cbi.pku.edu.cn
380 NCIR Non-Canonical Interactions in RNA http://prion.bchs.uh.edu/bp_type/
381 ncRNAs database Non-coding RNAs with regulatory functions http://biobases.ibch.poznan.pl/ncRNA/
705 NONCODE Database of noncoding RNAs http://bioinfo.ibp.ac.cn/NONCODE/index.htm
845 NPInter Noncoding RNA-protein interactions http://bioinfo.ibp.ac.cn/NPInter/index.php
1114 piRNABank Sequences and properties of Piwi-interacting RNAs (piRNAs) in human, mouse and rat http://pirnabank.ibab.ac.in/
564 Plant snoRNA DB snoRNA genes in plant species http://bioinf.scri.sari.ac.uk/cgi-bin/plant_snorna/home
240 PLANTncRNAs No longer maintained
241 PLMItRNA Mitochondrial tRNA genes in photosynthetic eukaryotes http://bighost.area.ba.cnr.it/PLMItRNA/
723 PolyA_DB Database of mammalian mRNA polyadenylation http://polya.umdnj.edu/
242 PseudoBase Database of RNA pseudoknots http://wwwbio.leidenuniv.nl/~Batenburg/PKB.html
1009 REDIdb An RNA editing database http://biologia.unical.it/py_script/search.html
382 Rfam Non-coding RNA families http://www.sanger.ac.uk/Software/Rfam/
243 RDP-II Ribosomal Database Project http://rdp.cme.msu.edu
244 RISSC Ribosomal Internal Spacer Sequence Collection http://egg.umh.es/rissc
245 RNA Modification DB Naturally modified nucleosides in RNA http://medlib.med.utah.edu/RNAmods/
900 RNA SSTRAND RNA secondary structure data and structural motifs http://www.rnasoft.ca/sstrand
630 RNAdb Mammalian noncoding RNA database http://ncrna.bioinformatics.com.au
862 RNAi codex Clones from mouse, human and rat shRNA libraries http://codex.cshl.org
1162 siRecords Experimentally tested mammalian siRNAs http://sirecords.umn.edu/siRecords/
629 siRNAdb Functional human siRNA sequences http://sirna.cgb.ki.se
247 Small RNA Database No longer maintained
869 snoRNA-LBME-db Human snoRNAs and Cajal body-specific RNAs (scaRNAs) http://www-snorna.biotoul.fr/
962 Sno/scaRNAbase Small nucleolar RNAs and cajal body-specific RNAs http://gene.fudan.sh.cn/snoRNAbase.nsf
248 SRPDB Signal recognition particle database http://rnp.uthct.edu/rnp/SRPDB/SRPDB.html
383 Subviral RNA DB Database of viroids and viroid-like RNAs http://subviral.med.uottawa.ca/
754 The Small Subunit rRNA Modification DB Modified nucleosides in small subunit rRNA http://library.med.utah.edu/SSUmods/
250 tmRDB tmRNA database http://rnp.uthct.edu/rnp/tmRDB/tmRDB.html
249 tmRNA Website tmRNA sequences and alignments http://www.indiana.edu/~tmrna
251 tRNA Sequences Has not been updated
1148 Vir-Mir db Prediction of viral microRNA candidate hairpins http://alk.ibms.sinica.edu.tw
254 Yeast snoRNA Database Yeast small nucleolar RNAs http://www.bio.umass.edu/biochem/rna-sequence/Yeast_snoRNA_Database/snoRNA_DataBase.html
3. Protein Sequence Databases
3.1. General sequence databases
163 EXProt Sequences of proteins with experimentally verified function http://www.cmbi.kun.nl/EXProt/
88 MIPS resources Munich Information Center for Protein Sequences databases http://mips.gsf.de/
542 NCBI Protein database All protein sequences: translated from GenBank and imported from other protein databases http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Protein
714 PA-GOSUB Protein sequences from model organisms, GO assignment and subcellular localization http://www.cs.ualberta.ca/~bioinfo/PA/
194 PIR Protein Information Resource http://pir.georgetown.edu
565 PRF Protein research foundation database of peptides http://www.prf.or.jp/en/index.shtml
790 TCDB Transporter protein classification database http://www.tcdb.org/
775 UniParc UniProt archive, a repository of all protein sequences http://www.uniprot.org/database/archive.shtml
318 UniProt Universal Protein knowledgebase, combined information from Swiss-Prot, TrEMBL, and PIR http://www.uniprot.org
197 UniProtKB\Swiss-Prot Formerly SwissProt, part of the UniProt knowledgebase http://www.expasy.org/sprot
198 UniProtKB\TrEMBL Now UniProt/TrEMBL, part of the UniProt knowledgebase http://www.uniprot.org/database/knowledgebase.shtml
776 UniRef Clustered sets of related sequences from UniProt http://www.uniprot.org/database/nref.shtml
1165 UniSave UniProtKB Sequence/Annotation Version Archive http://www.ebi.ac.uk/uniprot/unisave/
3.2. Protein properties
221 AAindex Physicochemical properties of amino acids http://www.genome.ad.jp/aaindex/
979 BindingDB Binding affinities of protein-ligand and other complexes http://www.bindingdb.org/bind/index.jsp
806 CyBase Proteins with cyclic backbones http://research1t.imb.uq.edu.au/cybase
885 dbPTM Information on post-translational modification of proteins http://dbptm.mbc.nctu.edu.tw/
914 iProLINK Annotated literature sources for protein features and names http://pir.georgetown.edu/iprolink
1093 MALISAM Manual alignments for structurally analogous motifs in proteins http://prodata.swmed.edu/malisam
1094 MegaMotifbase Structural motifs in protein families and superfamilies http://caps.ncbs.res.in/MegaMotifbase/index.html
954 PIDD Protein inter-atomic distances database http://pidd.math.iastate.edu
854 PINT Protein-protein interactions thermodynamic database http://pintdb.dyndns.org/index.html
856 PPD Experimentally-determined protein pKa values http://www.jenner.ac.uk/ppd/
1120 PPT-DB Protein Property Prediction and Testing Database http://redpoll.pharmacy.ualberta.ca/PPT_DB/public_html/PPT_main.html
280 ProTherm Thermodynamic data for wild-type and mutant proteins http://gibk26.bse.kyutech.ac.jp/jouhou/protherm/protherm.html
1176 PRTAD Protein residue torsion angle database http://www.math.iastate.edu/prtad
783 REFOLD Experimental data on protein refolding and purification http://refold.med.monash.edu.au
3.3. Protein localization and targeting
444 DBSubLoc - Database of protein Subcellular Localization http://www.bioinfo.tsinghua.edu.cn/dbsubloc.html
930 eSLDB eukaryotic proteins Subcellular Localization Database http://gpcr.biocomp.unibo.it/esldb
1021 InterFil Human Intermediate Filament database http://www.interfil.org
836 LOCATE Subcellular localization of mouse proteins http://locate.imb.uq.edu.au/
1022 MiCroKit Midbody, Centrosome and Kinetochore proteins http://bioinformatics.lcd-ustc.org/microkit/
226 MitoDrome Nuclear-encoded mitochondrial proteins of Drosophila http://www2.ba.itb.cnr.it/MitoDrome/
85 MitoRes Nuclear genes coding for mitochondrial proteins http://www2.ba.itb.cnr.it/MitoNuc/
375 NESbase Nuclear export signals database http://www.cbs.dtu.dk/databases/NESbase
376 NLSdb Nuclear localization signals http://cubic.bioc.columbia.edu/db/NLSdb/
704 NMPdb Nuclear matrix associated proteins database http://www.rostlab.org/db/NMPdb/
706 NOPdb: Nucleolar proteome database http://www.lamondlab.com/NOPdb/
369 NPD Nuclear Protein Database http://npd.hgu.mrc.ac.uk
182 Nuclear Receptor Resource Nuclear receptor superfamily http://nrr.georgetown.edu/NRR/nrrhome.htm
183 NUREBASE Nuclear hormone receptors database http://www.ens-lyon.fr/LBMC/laudet/nurebase/nurebase.html
789 NURSA Nuclear receptor signaling atlas http://www.nursa.org
734 PSORTdb Protein subcellular localization in bacteria http://db.psort.org/
745 Secreted Protein DB Secreted proteins from human, mouse and rat http://spd.cbi.pku.edu.cn
1014 SUBA Subcellular localisation of Arabidopsis proteins http://www.suba.bcs.uwa.edu.au/
587 THGS Transmembrane Helices in Genome Sequences http://pranag.physics.iisc.ernet.in/thgs/
1140 TopDB Topology Data Bank of transmembrane proteins http://topdb.enzim.hu
589 Transmembrane Protein Database Transmembrane proteins with experimentally-characterized transmembrane topologies http://bioinfo.si.hirosaki-u.ac.jp/~TMPDB/
3.4. Protein sequence motifs and active sites
374 ASC Active Sequence Collection http://bioinformatica.isa.cnr.it/ASC/
203 Blocks Alignments of conserved regions in protein families http://blocks.fhcrc.org
438 COMe Co-Ordination of Metals etc. http://www.ebi.ac.uk/come/
771 CoPS Comprehensive peptide signature database http://cops.igib.res.in/copsv2/index.html
440 CSA Catalytic Site Atlas http://www.ebi.ac.uk/thornton-srv/databases/CSA/
666 eBLOCKS Highly conserved protein sequence blocks http://fold.stanford.edu/eblocks/acsearch.html
452 eF-site Electrostatic surface of Functional site http://ef-site.protein.osaka-u.ac.jp/eF-site
206 eMOTIF Protein sequence motif determination and searches http://motif.stanford.edu/emotif
986 FireDB Functionally important residues in protein structures http://firedb.bioinfo.cnio.es/
207 InterPro Integrated resource of protein families, domains and functional sites http://www.ebi.ac.uk/interpro
179 Metalloprotein Site DB Metal-binding sites in metalloproteins http://metallo.scripps.edu/
209 O-GLYCBASE O- and C-linked glycosylation sites in proteins http://www.cbs.dtu.dk/databases/OGLYCBASE/
717 PDBSite 3D structure of protein functional sites http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-page+LibInfo+-newId+-lib+PDBSite
187 Phospho.ELM S/T/Y protein phosphorylation sites (former PhosphoBase) http://phospho.elm.eu.org/
1003 Phospho3D 3D structures of protein phosphorylation sites http://cbm.bio.uniroma2.it/p3d/
212 PRINTS Hierarchical gene family fingerprints http://umber.sbs.man.ac.uk/dbbrowser/PRINTS/
193 PROMISE Prosthetic centers and metal ions in protein active sites http://metallo.scripps.edu/PROMISE/
899 ProRule Functional and structural information on PROSITE profiles http://www.expasy.org/prosite/prorule.html
215 PROSITE Biologically-significant protein patterns and profiles http://www.expasy.org/prosite
732 ProTeus Signature sequences at the protein N- and C-termini http://www.proteus.cs.huji.ac.il
868 SitesBase Known ligand binding sites in the PDB http://www.modelling.leeds.ac.uk/sb/
3.5. Protein domain databases; protein classification
622 ADDA Database of protein domain classification http://ekhidna.biocenter.helsinki.fi/sqgraph/pairsdb
288 BAliBASE Benchmark database for comparison of multiple sequence alignments http://www-igbmc.u-strasbg.fr/BioInfo/BAliBASE2/index.html
978 Benchmark Protein classification benchmark collection: training/test sets for machine learning http://net.icgeb.org/benchmark/
786 BIOZON Database of gene and protein familiy classification http://biozon.org
204 CDD Conserved domain database, includes protein domains from Pfam, SMART, COG and KOG databases http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml
205 CluSTr Clusters of UniProt Knowledgebase and IPI proteins http://www.ebi.ac.uk/clustr/
7 COG Clusters of orthologous groups of proteins http://www.ncbi.nlm.nih.gov/COG
448 DomIns Database of Domain Insertions http://www.domins.org/
1068 eggNOG Evolutionary genealogy of genes: Non-supervised Orthologous Groups http://eggnog.embl.de
1069 EPGD Eukaryotic Paralog Group Database http://epgd.biosino.org:8080/EPGD/
963 EVEREST Automatically generated protein domain families http://www.everest.cs.huji.ac.il
671 FunShift Functional divergence between the subfamilies of a protein domain family http://FunShift.cgb.ki.se
470 FusionDB Database of bacterial and archaeal gene fusion events http://www.igs.cnrs-mrs.fr/FusionDB/
200 Hits Database of protein domains and motifs http://hits.isb-sib.ch
266 HSSP Homology-derived structures of proteins http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-page+LibInfo+-lib+HSSP
510 InterDom Putative protein domain interactions http://interdom.i2r.a-star.edu.sg/
208 iProClass Integrated protein classification database http://pir.georgetown.edu/iproclass/
844 MulPSSM Multiple PSSMs of structural and sequence families http://hodgkin.mbu.iisc.ernet.in/~mulpssm
1109 PairsDB Pairwise alignments of all sequences in UniProt http://pairsdb.csc.fi
274 PALI Phylogeny and alignment of homologous protein structures http://pauling.mbu.iisc.ernet.in/~pali
552 PANTHER Protein sequence evolution mapped to functions and pathways http://www.pantherdb.org
210 Pfam Protein families: Multiple sequence alignments and profile hidden Markov models of protein domains http://pfam.sanger.ac.uk/
981 PhyloFacts Phylogenomic analysis of protein families http://phylogenomics.berkeley.edu/phylofacts/
561 PIRSF Family/superfamily classification of whole proteins http://pir.georgetown.edu/pirsf/
214 ProDom Protein domain families http://prodom.prabi.fr/
216 ProtoMap Hierarchical classification of Swiss-Prot proteins http://protomap.cornell.edu
567 ProtoNet Hierarchical clustering of Swiss-Prot proteins http://www.protonet.cs.huji.ac.il/
217 SBASE Protein domain sequences and tools http://www.icgeb.org/sbase
867 SIMAP Similarity matrix of proteins: precomputed similarity data http://mips.gsf.de/simap/
1010 SISYPHUS Structural alignments for proteins with non-trivial relationships http://sisyphus.mrc-cpe.cam.ac.uk
218 SMART Simple modular architecture research tool: signalling, extracellular and chromatin-associated protein domains http://smart.embl-heidelberg.de
219 SUPFAM Grouping of sequence families into superfamilies http://pauling.mbu.iisc.ernet.in/~supfam
199 TIGRFAMs TIGR protein families adapted for functional annotation http://www.tigr.org/TIGRFAMs
3.6. Databases of individual protein families
157 ABCdb Archaeal and bacterial ABC transporter database http://www-abcdb.biotoul.fr
156 Aminoacyl-tRNA synthetases database Aminoacyl-tRNA synthetase database http://rose.man.poznan.pl/aars/index.html
1045 Animal Toxin DB Database of animal toxins http://protchem.hunnu.edu.cn/toxin
412 ARAMEMNON Arabidopsis thaliana membrane proteins and transporters http://aramemnon.botanik.uni-koeln.de
1166 BACTIBASE Database of bacteriocin natural antimicrobial peptides http://www.pfba-lab.org/bactibase
158 BacTregulators Transcriptional regulators of AraC and TetR families No longer maintained
976 BANMOKI Database of bacterial nucleoside monophosphate kinases http://www.ces.clemson.edu/compbio/databases/kinases
1057 ChromDB Chromatin-associated proteins in a broad range of organisms http://www.chromdb.org
923 cpnDB Chaperonin database http://cpndb.cbr.nrc.ca/
1154 CREMOFAC Database of chromatin remodeling factors http://www.jncasr.ac.in/cremofac/
364 CSDBase Cold Shock Domain database http://www.chemie.uni-marburg.de/~csdbase/
1168 CyMoBase Cytoskeletal and motor proteins database http://www.motorprotein.de/cymobase
1065 DB-PABP Experimentally characterized polyanion-binding proteins http://ppa.bcf.ku.edu/DB_PABP/
658 DCCP Database of Copper-Chelating Proteins http://sdbi.sdut.edu.cn/DCCP/en/index.php
945 Defensins Knowledgebase Antimicrobial peptides of the defensin family http://defensins.bii.a-star.edu.sg/
160 DExH/D Family DB DEAD-box, DEAH-box and DExH-box proteins http://www.helicase.net/dexhd/dbhome.htm
892 DSD Database of dehydrogenase stereospecificities http://www.jenner.ac.uk/DSD
161 Endogenous GPCR List G protein-coupled receptors; expression in cell lines http://www.tumor-gene.org/GPCR/gpcr.html
814 EROP-Moscow Database of Endogenous Regulatory OligoPeptides http://erop.inbi.ras.ru
162 ESTHER Esterases and other alpha/beta hydrolase enzymes http://bioweb.ensam.inra.fr/ESTHER/general?what=index
164 FUNPEP Low-complexity peptides capable of forming amyloid plaque http://www.cmbi.kun.nl/swift/FUNPEP/gergo/
166 GPCRDB G protein-coupled receptors database http://www.gpcr.org/7tm/
679 gpDB G-protein database: G-proteins and their interaction with GPCRs http://bioinformatics.biol.uoa.gr/gpDB
1085 Heme Protein DB Heme protein structure, heme type, axial ligands, and heme protein reduction potential (Em) values http://heme.chem.columbia.edu/heme.php
167 Histone Database Histone fold sequences and structures http://research.nhgri.nih.gov/histones/
365 HIV RT and Protease Sequence Database HIV reverse transcriptase and protease sequences http://hivdb.stanford.edu
169 Homeobox Page Homeobox proteins, classification, and evolution http://www.biosci.ki.se/groups/tbu/homeo.html
170 Homeodomain Resource Homeodomain sequences, structures, and related genetic and genomic information http://research.nhgri.nih.gov/homeodomain/
174 InBase Inteins (protein splicing elements) database: properties, sequences, bibliography http://www.neb.com/neb/inteins.html
518 KinG Kinases in Genomes: Ser/Thr/Tyr kinases encoded in the completely sequenced genomes http://hodgkin.mbu.iisc.ernet.in/~king
519 Knottin database Database of knottins, small proteins with an unusual "disulfide through disulfide" knot http://knottin.cbs.cnrs.fr/
176 LGICdb Ligand-gated ion channel subunit sequences database http://www.pasteur.fr/recherche/banques/LGIC/LGIC.html
368 Lipase Engineering DB Sequence, structure and function of lipases and esterases http://www.led.uni-stuttgart.de/
524 LOX-DB Mammalian, invertebrate, plant and fungal lipoxygenases http://www.dkfz-heidelberg.de/spec/lox-db/
177 MEROPS Database of proteolytic enzymes (peptidases) http://merops.sanger.ac.uk/
1105 NORINE Database of nonribosomal peptides http://bioinfo.lifl.fr/norine/
546 NucleaRDB Nuclear receptor superfamily http://www.receptors.org/NR/
184 Olfactory Receptor DB Sequences for olfactory receptor-like molecules http://senselab.med.yale.edu/senselab/ordb/
186 Peptaibol Peptaibol (antibiotic peptide) sequences http://www.cryst.bbk.ac.uk/peptaibol/
560 PhytoProt Clusters of (predicted) plant proteins http://urgi.versailles.inra.fr/phytoprot/
189 PLANT-PIs Plant protease inhibitors http://bighost.area.ba.cnr.it/PLANT-Pis
371 PlantsP/PlantsT Plant proteins involved in phosphorylation and transport http://plantsp.sdsc.edu
759 PLPMDB Pyridoxal-5'-phosphate dependent enzymes mutations http://www.studiofmp.com/plpmdb/
609 ProLysED Database of bacterial protease systems http://genome.ukm.my/prolyses/
192 Prolysis Proteases and natural and synthetic protease inhibitors http://delphi.phys.univ-tours.fr/Prolysis/
188 Protein kinase resource Protein kinase resource: sequences, enzymology, genetics and molecular and structural properties http://www.kinasenet.org/pkr/
224 REBASE Restriction enzymes and associated methylases http://rebase.neb.com/rebase/rebase.html
195 RNAse P Database Ribonuclease P sequences, alignments and structures http://www.mbio.ncsu.edu/RNaseP/home.html
901 RNRdb Ribonucleotide reductase database http://rnrdb.molbio.su.se/
573 RPG Ribosomal Protein Gene database http://ribosome.miyazaki-med.ac.jp/
575 RTKdb Receptor Tyrosine Kinase database http://pbil.univ-lyon1.fr/RTKdb/
372 SDAP Structural database of allergenic proteins and food allergens http://fermi.utmb.edu/SDAP
1131 SelenoDB Database of selenoprotein genes, proteins and SECIS elements http://www.selenodb.org/
196 SENTRA Sensory signal transduction proteins http://compbio.mcs.anl.gov/sentra/
373 SEVENS 7-transmembrane helix receptors (G-protein-coupled) http://sevens.cbrc.jp/1.20/
1137 Telomerase database Sequences and structures of the RNA and protein subunits of telomerase, mutations of telomerase components http://telomerase.asu.edu
311 TransportDB Predicted membrane transporters in complete genomes, classified according to the TC classification system http://www.membranetransport.org
399 VKCDB Voltage-gated K+ Channel Database http://vkcdb.biology.ualberta.ca/
202 Wnt Database Wnt proteins and phenotypes http://www.stanford.edu/~rnusse/wntwindow.html
4. Structure Databases
4.1. Small molecules
402 AANT Amino Acid - Nucleotide interaction database http://aant.icmb.utexas.edu/
646 ChEBI Chemical entities of biological interest http://www.ebi.ac.uk/chebi/
1024 ChemBank Structures and biological activities of small organic molecules http://chembank.broad.harvard.edu/
1023 ChemDB 3D structures and properties of small molecules http://cdb.ics.uci.edu
261 CSD Cambridge Structural Database http://www.ccdc.cam.ac.uk/prods/csd/csd.html
360 Het-PDB Navi Hetero-atoms in protein structures http://daisy.bio.nagoya-u.ac.jp/golab/hetpdbnavi.html
265 HIC-Up Hetero-compound Information Centre - Uppsala http://xray.bmc.uu.se/hicup/
111 Klotho Collection and categorization of biological compounds http://www.biocheminfo.org/klotho/
113 LIGAND Chemical compounds and reactions in biological pathways http://www.genome.ad.jp/ligand/
615 PDB-Ligand 3D structures of small molecules bound to proteins and nucleic acids http://www.idrtech.com/PDB-Ligand/
735 PubChem Structures and biological activities of small organic molecules http://pubchem.ncbi.nlm.nih.gov/
1127 R.E.DD.B. RESP and ESP atomic charges and force field libraries for small molecules and molecular fragments http://q4md-forcefieldtools.org/REDDB
4.2. Carbohydrates
977 BCSDB/Glycoscience Bacterial Carbohydrate Structure DataBase http://www.glyco.ac.ru/bcsdb/start.shtml
429 CarbBank CCSD - Complex Carbohydrate Structure Database http://bssv01.lancs.ac.uk/gig/pages/gag/carbbank.htm
652 CSS Carbohydrate Structure Suite: carbohydrate 3D structures http://www.dkfz.de/spec/css/
486 Glycan Carbohydrate database, part of the KEGG system http://glycan.genome.ad.jp/
1080 Glycoconjugate Data Bank Annotated structures of glycan molecules http://daisy2.nagahama-i-bio.ac.jp/structures/
988 GlycoMaps DB Conformational maps of disaccharides http://www.glycosciences.de/modeling/glycomapsdb/
292 GlycoSuiteDB N- and O-linked glycan structures and biological sources http://www.glycosuite.com
535 Monosaccharide Browser Space filling Fischer projections of monosaccharides http://www.terravivida.com/vivida/monosaccharide/
300 SWEET-DB Annotated carbohydrate structure and substance information http://www.dkfz-heidelberg.de/spec2/sweetdb/
4.3. Nucleic acid structure
1082 Greglist G-quadruplex motifs and potentially G-quadruplex regulated genes http://tubic.tju.edu.cn/greglist/
1090 ITS2 Predicted structures of internal transcribed spacer 2 (ITS2) molecules http://its2.bioapps.biozentrum.uni-wuerzburg.de/ITS2_db.html
272 NDB Nucleic acid-containing structures http://ndbserver.rutgers.edu/
273 NTDB Thermodynamic data for nucleic acids http://ntdb.chem.cuhk.edu.hk
1126 QuadBase G-quadruplex motifs in the promoters of human, chimpanzee, rat, mouse and bacterial genes http://quadbase.igib.res.in/
1129 RNA FRABASE Database of 3D RNA fragments within known RNA structures http://rnafrabase.ibch.poznan.pl/
387 RNABase RNA-containing structures from PDB and NDB http://www.rnabase.org
1130 RNAJunction RNA structural elements: helical junctions, internal loops, bulges and loop-loop interactions http://rnajunction.abcc.ncifcrf.gov
908 SARS-CoV RNA SSS Predicted secondary structures of SARS coronavirus RNA http://www.liuweibo.com/sarsdb/
283 SCOR Structural classification of RNA: RNA motifs by structure, function and tertiary interactions http://scor.lbl.gov
4.4. Protein structure
401 3D-Genomics Structural annotations for complete proteomes http://www.sbg.bio.ic.ac.uk/3dgenomics
633 3DID 3D interacting domains http://gatealoy.pcb.ub.es/3did/
413 ArchDB Automated classification of protein loop structures http://gurion.imim.es/archdb
255 ASTRAL Sequences of domains of known structure, selected subsets and sequence-structure correspondences http://astral.berkeley.edu/
1047 AutoPSI Automated structural classification of protein sequences http://www.bio.ifi.lmu.de/AutoPSIDB
257 BioMagResBank NMR spectroscopic data from proteins, peptides, and nucleic acids http://www.bmrb.wisc.edu/
384 CADB Conformational Angles DataBase of Proteins http://cluster.physics.iisc.ernet.in/cadb/
258 CATH Protein domain structures database http://www.cathdb.info/
259 CE Combinatorial Extension method to compute and review 3D protein structure alignments http://cl.sdsc.edu/ce.html
260 CKAAPs DB Conserved Key Amino Acid Positions Database No longer maintained
882 CoC Central Universally conserved residues in protein folds http://kulibin.mit.edu/coc/
1059 ColiSNP Mapping non-synonymous SNPs on protein structures http://yayoi.kansai.jaea.go.jp/colisnp
883 Columba Annotation of protein structures from the PDB http://www.columba-db.de
442 Dali database Fold classification based on structural alignment of proteins http://ekhidna.biocenter.helsinki.fi/dali/start
1169 DBAli Database of structure alignments http://salilab.org/DBAli/
385 Decoys-R-Us Computer-generated protein conformations based on sequence data http://dd.compbio.washington.edu/
447 DisProt Database of Protein Disorder http://divac.ist.temple.edu/disprot
809 DMAPS Database of multiple alignments for protein structures http://bioinformatics.albany.edu/~dmaps
264 DSDBASE Disulfide Database http://www.ncbs.res.in/~faculty/mini/dsdbase/dsdbase.html
386 DSMM A Database of Simulated Molecular Motions http://projects.villa-bosch.de/dbase/dsmm/
456 E-MSD EBI-Macromolecular Structure Database http://www.ebi.ac.uk/msd
818 FSN Flexible structural neighborhood, structural neighbors of proteins identified by FATCAT tool http://fatcat.ljcrf.edu/fatcat-cgi/cgi/struct_neibor/fatcatStructNeibor.pl
469 FSSP Superseded by the Dali database, no. 442
472 Gene3D Precalculated structural assignments for whole genomes http://cathwww.biochem.ucl.ac.uk:8080/Gene3D/
489 Genomic Threading DB Structural annotations of complete genomes http://bioinf.cs.ucl.ac.uk/GTD
322 GTOP Protein fold predictions from genome sequences http://spock.genes.nig.ac.jp/~genome/gtop.html
498 HOMSTRAD Homologous structure alignment database: curated structure-based alignments for protein families http://www-cryst.bioc.cam.ac.uk/homstrad
267 IMB Jena Image Library Visualization and analysis of 3D biopolymer structures http://www.imb-jena.de/IMAGE.html
502 IMGT/3Dstructure-DB 3D structures of Immunoglobulins, T cell receptors, and MHC proteins http://imgt3d.igh.cnrs.fr/
829 IMOTdb Spatially interacting motifs in proteins http://caps.ncbs.res.in/imotdb/
269 LPFC Library of protein family core structures http://helix-web.stanford.edu/LPFC/
270 MMDB All experimentally-determined 3D structures, linked to NCBI Entrez http://www.ncbi.nlm.nih.gov/Structure/
331 ModBase Annotated comparative protein structure models http://salilab.org/modbase
262 MolMovDB Database of Macromolecular Movements http://bioinfo.mbb.yale.edu/MolMovDB/
107 MPID MHC-Peptide Interaction Database http://surya.bic.nus.edu.sg/mpidt
275 PASS2 Structural motifs of protein superfamilies http://www.ncbs.res.in/~faculty/mini/campass/pass2.html
276 PDB Protein Data Bank: all known protein structures http://www.pdb.org/
619 PDB_TM Transmembrane proteins with known 3D structure http://pdbtm.enzim.hu/
277 PDB-REPRDB Representative protein chains, based on PDB entries http://mbs.cbrc.jp/pdbreprdb-cgi/reprdb_menu.pl
278 PDBsum Summaries and analyses of PDB structures http://www.ebi.ac.uk/thornton-srv/databases/pdbsum/
557 PepConfDB Database of peptide conformations http://www.peptidome.org/products/list.htm
719 PFD Protein Folding Database : Experimental data on protein folding http://www.foldeomics.org/pfd/public_html/index.php
855 PMDB 3D protein models obtained from structure predictions http://www.caspur.it/PMDB/
281 RESID Post-translational modifications of proteins http://www.ebi.ac.uk/RESID/
740 S4 Structure-based Sequence Alignments of SCOP Superfamilies http://compbio.mds.qmw.ac.uk/~james/S4.shtml
282 SCOP Structural classification of proteins http://scop.mrc-lmb.cam.ac.uk/scop
863 SCOPPI Structural classification of protein-protein interfaces http://www.scoppi.org
284 SLoop Classification of protein loops http://www-cryst.bioc.cam.ac.uk/~sloop/
530 SSToSS Sequence-Structural Templates of Single-member Superfamilies http://caps.ncbs.res.in/SSTOSS/index.htm
785 STING Report Amino acid properties in proteins of known structure http://sms.cbi.cnptia.embrapa.br/SMS/STINGm/SMSReport/
583 Structure Superposition Database Pairwise superpositions of 115 TIM-barrel structures http://ssd.rbvi.ucsf.edu/
285 SUPERFAMILY Assignments of proteins to structural superfamilies http://supfam.org/SUPERFAMILY/
584 SURFACE Surface residues and functions annotated, compared and evaluated: a database of protein surface patches http://cbm.bio.uniroma2.it/surface
585 SWISS-MODEL Repository 3D protein structure models generated by automated homology modeling using SWISS-MODEL http://swissmodel.expasy.org/repository
764 TargetDB Target data from worldwide structural genomics projects http://targetdb.pdb.org/
938 TMBETA-GENOME Beta-barrel membrane proteins encoded in various genomes http://tmbeta-genome.cbrc.jp/annotation/
941 TOPOFIT-DB Protein structural alignments based on the TOPOFIT method http://mozart.bio.neu.edu/topofit/
310 TOPS Topology Of Protein Structures http://www.tops.leeds.ac.uk
5. Genomics Databases (non-human)
5.1. Genome annotation terms, ontologies and nomenclature
915 BioThesaurus A collection of gene/protein names and associated sequences http://pir.georgetown.edu/iprolink/biothesaurus
1075 FunSimMat Gene Ontology-based functional similarity values for proteins and protein families http://gotax.bioinf.mpi-inf.mpg.de/funsimmat/
487 GO Gene ontology consortium database http://www.geneontology.org/
389 GOA Gene Ontology Annotation http://www.ebi.ac.uk/GOA
939 GOPaD Gene Ontology Partition Database http://bcl.med.harvard.edu/proj/gopart
73 HGNC Database The HUGO Gene Nomenclature Database (formerly Genew) http://www.genenames.org/
513 IUBMB Nomenclature database Nomenclature of enzymes, membrane transporters, electron transport proteins and other proteins http://www.chem.qmul.ac.uk/iubmb/
514 IUPAC Nomenclature database Nomenclature of biochemical and organic compounds approved by the IUBMB-IUPAC Joint Commission http://www.chem.qmul.ac.uk/iupac/
515 IUPHAR-RD International Union of Pharmacology recommendations on receptor nomenclature and drug classification http://www.iuphar-db.org/iuphar-rd/
926 Plant Ontology DB Controlled vocabulary of plant structures and growth stages http://www.plantontology.org
358 SOURCE Functional genomics resource for human, mouse and rat http://source.stanford.edu
906 TreeBase Phylogenetic trees and the data matrices used to generate them http://www.treebase.org/
317 UMLS Unified medical language system Requires user registration
5.2. Taxonomy and identification
1018 GeneTrees Pre-compiled alignments and gene phylogenies for a variety of taxonomic groups http://genetrees.vbi.vt.edu
78 ICB gyrB database for identification of bacteria http://seasquirt.mbio.co.jp/icb/
1088 IDBD Infectious Disease Biomarker Database http://biomarker.korea.ac.kr
297 NCBI Taxonomy Browser Names of all organisms that are represented in GenBank http://www.ncbi.nlm.nih.gov/Taxonomy/taxonomyhome.html
299 RIDOM Ribosomal Differentiation of Medical Microorganisms http://www.ridom.de/
1135 SuperCAT Database for multilocus sequence typing analysis of the Bacillus cereus group of bacteria http://mlstoslo.uio.no/
301 Tree of Life Information on phylogeny and biodiversity http://phylogeny.arizona.edu/tree/phylogeny.html
965 VNTR Locus DB Bacterial Variable Number Tandem Repeat locus database http://vntr.csie.ntu.edu.tw/
5.3. General genomics databases
641 BacMap Picture atlas of annotated bacterial genomes http://wishart.biology.ualberta.ca/BacMap/
650 CoGenT++ Complete genome tracking: Predicted peptides from fully sequenced genomes http://cgg.ebi.ac.uk/cgg/cpp_sitemap.html
445 DEG Database of Essential Genes http://tubic.tju.edu.cn/deg
1172 diArk Database of eukaryotic sequencing projects http://www.diark.org/diark/
451 EBI Genomes EBI’s collection of databases for the analysis of complete and unfinished viral, pro- and eukaryotic genomes http://www.ebi.ac.uk/genomes
458 Entrez Genomes NCBI’s collection of databases for the analysis of complete and unfinished viral, pro- and eukaryotic genomes http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Genome
461 ERGO-Light Integrated biochemical data on 10 bacterial genomes: Publicly-available portion of the ERGO database http://www.ergo-light.com/
674 GenDiS Genomic distribution of protein structural superfamilies http://caps.ncbs.res.in/gendis/home.html
327 GeneNest Gene indices of human, mouse, zebrafish, etc. http://genenest.molgen.mpg.de/
1077 GenoList An integrated environment for comparative analysis of microbial genomes http://genolist.pasteur.fr/
484 Genome Information Broker DDBJ’s collection of genome databases http://gib.genes.nig.ac.jp
678 Genome Reviews Integrated view of complete genomes http://www.ebi.ac.uk/GenomeReviews/
916 Genome Project DB NCBI's database of large-scale genome sequencing projects http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=genomeprj
75 GOLD Genomes online database: a listing of completed and ongoing genome projects http://www.genomesonline.org/
830 HOINVGEN Homologous invertebrate genes http://pbil.univ-lyon1.fr/databases/hoinvgen/HOINVGEN.html
690 Inparanoid Database of eukaryotic orthologs http://inparanoid.cgb.ki.se/
223 Integr8 Functional classification of proteins in whole genomes http://www.ebi.ac.uk/integr8/
777 KaryotypeDB Karyotype and chromosome data for animal and plant species http://www.nenno.it/karyotypedb/
112 KEGG Kyoto Encyclopedia of Genes and Genomes: databases on genes, proteins, and metabolic pathways http://www.genome.ad.jp/kegg
528 MBGD Microbial genome database for comparative analysis http://mbgd.genome.ad.jp/
114 MetaCyc Metabolic pathways and enzymes from various organisms http://metacyc.org/
1103 Narcisse Conserved syntenies for various animal, plant and bacterial genomes http://narcisse.toulouse.inra.fr
703 NegProt Negative Proteome: A tool for comparison of complete proteomes http://superfly.ucsd.edu/negprot
1040 NMPDR Database for functional annotation and comparative analysis of microbial genomes http://www.nmpdr.org
1106 OPTIC Orthologous and Paralogous Transcripts in Clades http://genserv.anat.ox.ac.uk/
549 ORFanage Orphan ORFs (ORFs with no homologs) in microbial genomes No longer maintained
1108 OrthoDB An hierarchical catalog of orthologous proteins in metazoa http://cegg.unige.ch/orthodb/browse
847 OrthoMCL Orthologous protein clusters from multiple genomes http://orthomcl.cbil.upenn.edu
715 PartiGeneDB Assembled partial genomes for ~250 eukaryotic organisms http://www.partigenedb.org/
354 PEDANT Results of an automated analysis of genomic sequences http://pedant.gsf.de
377 PEP Predictions for Entire Proteomes http://cubic.bioc.columbia.edu/pep/
1113 PhylomeDB Experimentally validated and predicted serine phosphorylation sites in Arabidopsis thaliana http://phylomedb.bioinfo.cipf.es
118 PUMA2 Metabolic analysis of complete microbial genomes http://compbio.mcs.anl.gov/puma2/
582 STRING Predicted functional associations between proteins http://string.embl.de/
66 TIGR Comprehensive Microbial Resource Various data on complete microbial genomes: Uniform annotation, properties of DNA and predicted proteins http://www.tigr.org/tigr-scripts/CMR2/CMRHomePage.spl
5 TIGR Gene Indices Organism-specific databases of EST and gene sequences http://www.tigr.org/tdb/tgi.shtml
99 TIGR Microbial DB A list of microbial genome sequencing projects No longer maintained
877 VBI Microbial Database Virginia Bioinformatics Institute microbial database http://phytophthora.vbi.vt.edu
5.4. Viral genome databases
1051 BioHealthBase Host-pathogen interactions of influenza virus http://dev.biohealthbase.org/GSearch/PrototypeIndex.jsp
1061 CoVDB Database of coronavirus genes and genomes http://covdb.microbiology.hku.hk
810 DPVweb Descriptions of plant viruses http://www.dpvweb.net
1034 euHCVdb European Hepatitis C Virus database http://euhcvdb.ibcp.fr
492 HCV Database Hepatitis C Virus (HCV) Sequence Database http://hcv.lanl.gov/
473 HCVdb Hepatitis C Virus Database http://hepatitis.ibcp.fr/
972 HepSeq Epidemiological, clinical, and sequence data on the Hepatitis B virus http://www.hpa-bioinfodatabases.org.uk/ hepatitis_open/main.php
495 HERVd Human Endogenous Retrovirus database http://herv.img.cas.cz
497 HIV Drug Resistance Database HIV mutations that confer resistance to anti-HIV drugs http://resdb.lanl.gov/Resist_DB/default.htm
168 HIV Molecular Immunology Database HIV epitopes http://hiv-web.lanl.gov/immunology/
990 HIV Positive Selection Mutation Database Positively selected mutations in HIV-1 protease and reverse transcriptase http://bioinfo.mbi.ucla.edu/HIV
909 Influenza Virus Resource Protein and nucleotide sequences of the influenza virus http://www.ncbi.nlm.nih.gov/genomes/FLU/FLU.html
993 IVDB Influenza Virus Database : Annotated sequences and geographic distribution of the influenza virus http://influenza.genomics.org.cn
602 NCBI Viral Genomes Viral genome resource at NCBI http://www.ncbi.nlm.nih.gov/genomes/VIRUSES/viruses.html
725 Poxvirus.org Poxvirus genomic sequences and gene annotation http://www.poxvirus.org
750 T4-like genome DB Sequences of T4-like bacteriophages from various sources http://phage.bioc.tulane.edu
201 VIDA Homologous viral protein families database http://www.biochem.ucl.ac.uk/bsm/virus_database/VIDA.html
761 VIPERdb Virus particle explorer: Virus capsid structures http://viperdb.scripps.edu/
798 Viral Bioinformatics Resource Center Virus orthologous genes, gene families and genomes http://www.biovirus.org
397 VirGen Curated database for complete viral genome sequences http://bioinfo.ernet.in/virgen/virgen.html
1039 ViTa microRNAs targets of the influenza virus http://vita.mbc.nctu.edu.tw
5.5. Prokaryotic genome databases
5.5.1. General
1044 AlterORF Database of alternate open reading frames http://www.cienciavida.cl/alterorf/
641 BacMap Picture atlas of annotated bacterial genomes http://wishart.biology.ualberta.ca/BacMap
884 Comparative Genometrics DNA walks, nucleotide skews and other biometric measures of prokaryotic genomes http://www.unil.ch/comparativegenometrics/
70 EMGlib Enhanced microbial genomes library: Completely sequenced genomes of unicellular organisms http://pbil.univ-lyon1.fr/emglib/emglib.html
328 GeneDB Curated database for various Sanger-sequenced genomes http://www.genedb.org/
611 Genome Atlas DNA structural properties of sequenced genomes http://www.cbs.dtu.dk/services/GenomeAtlas/
1084 HEG-DB Predicted highly expressed genes in prokaryotic genomes http://genomes.urv.cat/HEG-DB
352 HGT-DB Horizontal Gene Transfer-DataBase http://www.fut.es/~debb/HGT/
828 IMG Comparative analysis of microbial genomes sequenced at the DOE Joint Genome Institute http://img.jgi.doe.gov/
1089 IMG/M A data management and analysis system for metagenomes http://img.jgi.doe.gov/m
826 Interrupted coding sequences DB Interrupted coding sequences: frameshifts, stop codons, sequencing errors in microbial genomes http://www-bio3d-igbmc.u-strasbg.fr/ICDS/
837 MeGX Marine ecological genomix: genomics and metagenomics of marine bacteria http://www.Megx.net
614 MetaGrowth Growth requirements of bacterial pathogens http://igs-server.cnrs-mrs.fr/axenic/
959 MiST Microbial Signal Transduction database http://genomics.ornl.gov/mist/
720 PGTdb Prokaryotic growth temperature database http://pgtdb.csie.ncu.edu.tw/
43 RRNDB rRNA operon numbers in various prokaryotes http://rrndb.cme.msu.edu
1160 Roundup Repository of orthologs and corresponding evolutionary distances http://rodeo.med.harvard.edu/tools/roundup
866 SIDDBase Stress-induced DNA duplex destabilization profiles of complete microbial genomes http://www.genomecenter.ucdavis.edu/benham/siddbase/
426 xBase A family of group-specific bacterial genome databases, includes coliBASE, CampyDB, ClostriDB, MycoDB, PseudoDB and others http://xbase.bham.ac.uk/
5.5.2. Escherichia coli
415 ASAP A Systematic Annotation Package https://asap.ahabs.wisc.edu/annotation/php/ASAP1.htm
428 CCDB CyberCell Database http://redpoll.pharmacy.ualberta.ca/CCDB
436 coliBase Database for E. coli, Salmonella and Shigella http://colibase.bham.ac.uk/
437 Colibri http://genolist.pasteur.fr/Colibri/
623 EchoBASE Post-genomic studies of Escherichia coli http://www.ecoli-york.org/
108 EcoCyc E. coli K12 genes, pathways, transporters, and gene regulation http://ecocyc.org/
69 EcoGene Sequence and literature data on E. coli genes and proteins http://ecogene.org/
1070 ERIC Enteropathogen Resource Integration Center http://www.ericbrc.org
462 Essential genes in E. coli A list of genes essential for viability of E. coli http://www.genome.wisc.edu/resources/essential.htm
482 GenoBase Functional genomic aAnalysis of E. coli in Japan http://ecoli.aist-nara.ac.jp/
165 GenProtEC E. coli K12 genome and proteome database http://genprotec.mbl.edu