| ||||||||||||||||||||
Supplementary Table 1. NAR Molecular Biology Database Collection: 2008 updatea
| Nob | Database name | Full name and/or description | URL | |
| 1. Nucleotide Sequence Databases | ||||
| 1.1. International Nucleotide Sequence Database Collaboration | ||||
| 1 | DDBJ - DNA Data Bank of Japan | All known nucleotide and protein sequences | http://www.ddbj.nig.ac.jp | |
| 2 | EMBL Nucleotide Sequence Database | All known nucleotide and protein sequences | http://www.ebi.ac.uk/embl.html | |
| 3 | GenBank® | All known nucleotide and protein sequences | http://www.ncbi.nlm.nih.gov/Entrez | |
| 1.2. Coding and coding DNA: genes, motifs and regulatory sites | ||||
| 403 | ACLAME | A classification of genetic mobile elements | http://aclame.ulb.ac.be/ | |
| 337 | CORG | Comparative Regulatory Genomics: conserved non-coding blocks in vertebrate species | http://corg.molgen.mpg.de | |
| 30 | CUTG | Codon Usage Tabulated from GenBank | http://www.kazusa.or.jp/codon/ | |
| 1157 | ECRbase | Database of Evolutionary Conserved Regions, promoters, and transcription factor binding sites | http://ecrbase.dcode.org/ | |
| 668 | Entrez Gene | Gene-centered information at NCBI | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene | |
| 669 | FESD | Functional Element SNPs Database: SNPs located within promoters, UTRs, etc., of human genes | http://sysbio.kribb.re.kr/FESD/ | |
| 468 | FREP | Functional Repeats in mouse cDNAs | http://facts.gsc.riken.go.jp/FREP/ | |
| 480 | Genetic Codes | Genetic codes in various organisms and organelles | http://www.ncbi.nlm.nih.gov/Taxonomy/Utils/wprintgc.cgi?mode=c | |
| 1079 | GISSD | Group I Intron Sequence and Structure Database | http://www.rna.whu.edu.cn/gissd | |
| 1083 | GyDB | Gypsy database of mobile genetic elements | http://gydb.uv.es/gydb/intro.htm | |
| 825 | HumHot | Human meiotic recombination hot spots | http://www.jncasr.ac.in/humhot/ | |
| 932 | InSatDb | Sequences and properties of insect microsatellites | http://www.cdfd.org.in/insatdb | |
| 832 | ISfinder | Insertion sequences from bacteria and archaea | http://www-is.biotoul.fr | |
| 512 | Islander | Pathogenicity islands and prophages in bacterial genomes | http://www.indiana.edu/~islander | |
| 697 | L1Base | Functional annotation and prediction of LINE-1 elements | http://line1.molgen.mpg.de | |
| 19 | MethDB | DNA methylation data, patterns and profiles | http://www.methdb.de | |
| 343 | MICdb | Prokaryotic microsatellites | http://210.212.212.7/MIC/index.html | |
| 707 | NPRD | Nucleosome Positioning Region Database | http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?page+ LibInfo+-id+2Xnp11RCiPU+-lib+NUCLEOSOME | |
| 931 | OriDB | DNA Replication Origin Database: Confirmed and predicted sites | http://www.oridb.org/ | |
| 551 | PACRAT | Archaeal and bacterial intergenic sequence features | No longer maintained | |
| 608 | PANDIT | Protein and associated nucleotide domains with inferred trees | http://www.ebi.ac.uk/goldman-srv/pandit/ | |
| 933 | Patome | Annotated sequences from patents and patent applications | http://www.patome.org | |
| 958 | PolymiRTS | Polymorphism in microRNA Target Site | http://compbio.utmem.edu/miRSNP/ | |
| 1007 | PseudoGene.org | Pseudogenes in eukaryotic and prokaryotic genomes | http://www.pseudogene.org/ | |
| 21 | RECODE | Genes using programmed translational recoding in their expression | http://recode.genetics.utah.edu | |
| 391 | RefSeq | Reference Sequence database: an integrated, non-redundant set of genomic DNA, RNA, and protein sequences | http://www.ncbi.nlm.nih.gov/RefSeq/ | |
| 1019 | RetrOryza | LTR-retrotransposons in rice | http://www.retroryza.org | |
| 309 | S/MARt DB | Nuclear scaffold/matrix attached regions | http://smartdb.bioinf.med.uni-goettingen.de/ | |
| 1013 | SNPSTR | Microsatellite compound markers in 5 vertebrate genomes | http://www3.imperial.ac.uk/theoreticalgenomics/data-software | |
| 47 | STRBase | Short tandem DNA repeats database | http://www.cstl.nist.gov/div831/strbase/ | |
| 929 | Synthetic Gene DB | Synthetic genes described in peer-reviewed literature | http://www.evolvingcode.net/codon/sgdb/index.php | |
| 588 | TIGR plant repeat DB | Classification of repetitive sequences in plant genomes | http://www.tigr.org/tdb/e2k1/plant.repeats | |
| 1141 | TranspoGene | Transposed elements influence on the transcriptome of seven vertebrates and invertebrates | http://transpogene.tau.ac.il/ | |
| 1035 | TRDB | Tandem repeats in genomic DNA | http://tandem.bu.edu/cgi-bin/trdb/trdb.exe | |
| 1143 | UgMicroSatdb | UniGene MicroSatellite database: short tandem repeats from various eukaryotic genomes | http://ipu.ac.in/usbt/UgMicroSatdb.htm | |
| 320 | UniVec | Vector sequences, adapters, linkers and primers used in DNA cloning, used to check for vector contamination | http://www.ncbi.nlm.nih.gov/VecScreen/UniVec.html | |
| 252 | UTRdb/UTRsite | 5'- and 3'-UTRs of eukaryotic mRNAs | http://bighost.area.ba.cnr.it/BIG/UTRHome/ | |
| 1146 | UTRome | 3'UTRs and their functional elements in C. elegans | http://www.utrome.org | |
| 302 | Vectordb | Characterization and classification of nucleic acid vectors | http://seq.yeastgenome.org/vectordb/ | |
| 968 | VISTA Enhancer Browser | Enhancer elements in the human genome | http://enhancer.lbl.gov/ | |
| 1.3. Gene structure, introns and exons, splice sites | ||||
| 414 | ASAP II | Comparative analysis of alternative splicing in animal species | http://bioinfo.mbi.ucla.edu/ASAP2/ | |
| 10 | ASDB | Alternative Splicing Database: protein products and expression patterns of alternatively-spliced genes | http://hazelton.lbl.gov/~teplitski/alt/ | |
| 639 | ASHESdb | Alternatively Spliced Human genes by Exon Skipping | http://sege.ntu.edu.sg/wester/ashes/ | |
| 28 | ASTD | Alternative Splicing and Transcript Diversity database | http://www.ebi.ac.uk/astd/ | |
| 920 | ATD | Alternate transcript diversity database | Superseded by ASTD, no. 28 | |
| 803 | ChimerDB | Chimeric (fusion) sequences in human, rat and mouse | http://genome.ewha.ac.kr/ChimerDB/ | |
| 450 | EASED | Extended Alternatively Spliced EST Database | http://eased.bioinf.mdc-berlin.de/ | |
| 667 | ECgene | Genome annotation for alternative splicing | http://genome.ewha.ac.kr/ECgene/ | |
| 631 | EDAS | EST-derived alternative splicing database | http://www.ig-msk.ru:8005/EDAS/ | |
| 32 | EID | Exon-intron database | http://www.meduohio.edu/bioinfo/eid/ | |
| 34 | ExInt | Exon–intron structure of eukaryotic genes | http://sege.ntu.edu.sg/wester/exint/ | |
| 913 | ExtraTRAIN | Extragenic regions and transcriptional regulators in bacteria and archaea | http://www.era7.com/ExtraTrain/ | |
| 782 | FUGOID | Functional genomics of organelle introns database | http://web.austin.utexas.edu/fugoid/introndata/main.htm | |
| 970 | H-DBAS | Human database of alternative splicing | http://jbirc.jbic.or.jp/h-dbas/ | |
| 821 | Hollywood | Exon annotation database | http://hollywood.mit.edu | |
| 36 | HS3D | Homo Sapiens Splice Sites Dataset | http://www.sci.unisannio.it/docenti/rampone/ | |
| 238 | Intronerator | Alternative splicing in C. elegans and C. briggsae | http://hgwdev-hiram.cse.ucsc.edu/IntronWS120/ | |
| 1122 | ProSAS | Protein Structure and Alternative Splicing: effects of alternative splicing events on protein structure | http://services.bio.ifi.lmu.de/ProSAS | |
| 46 | SpliceDB | Canonical and non-canonical mammalian splice sites | http://www.softberry.com/berry.phtml?topic=splicedb&group=data&subgroup=spldb | |
| 746 | SpliceInfo | Modes of alternative splicing in human genome | http://spliceinfo.mbc.nctu.edu.tw/ | |
| 580 | SpliceNest | Visualizing Splicing of Genes from EST Data | http://splicenest.molgen.mpg.de/ | |
| 927 | TassDB | TAndem Splice Site Database | http://helios.informatik.uni-freiburg.de/TassDB/ | |
| 937 | U12DB | Database of orthologous U12-type spliceosomal introns | http://genome.imim.es/cgi-bin/u12db/u12db.cgi | |
| 305 | Xpro | Eukaryotic protein-encoding DNA sequences, both intron-containing and intron-less genes | http://origin.bic.nus.edu.sg/xpro/ | |
| 342 | Yeast Intron Database | Ares lab database of splicesomal introns in S. cerevisiae | http://www.cse.ucsc.edu/research/compbio/yeast_introns.html | |
| 1.4. Transcriptional regulator sites and transcription factors | ||||
| 795 | ABS | Annotated regulatory binding sites from orthologous promoters | http://genome.imim.es/datasets/abs2005/ | |
| 231 | ACTIVITY | Functional DNA/RNA site activity | http://wwwmgs.bionet.nsc.ru/mgs/systems/activity/ | |
| 308 | ASPD | Artificial selected proteins/peptides database | http://wwwmgs.bionet.nsc.ru/mgs/gnw/aspd/ | |
| 805 | CisRed | Human regulatory DNA sequence motifs | http://www.cisred.org/ | |
| 1058 | CMGSDB | Computational models for gene silencing in C. elegans | https://bioinformatics.cs.vt.edu/cmgs/CMGSDB/ | |
| 1062 | COXPRESdb | Coexpressed genes and networks in human and mouse | http://coxpresdb.hgc.jp/ | |
| 1063 | CTCF Binding Site DB | Experimentally identified and predicted CTCF binding sties | http://insulatordb.utmem.edu/ | |
| 807 | DBD | Transcription factor prediction database | http://www.transcriptionfactor.org/ | |
| 31 | DBTBS | Bacillus subtilis promoters and transcription factors | http://dbtbs.hgc.jp/ | |
| 591 | DBTSS | Database of transcriptional start sites | http://dbtss.hgc.jp/ | |
| 663 | DoOP | Databases of Orthologous Promoters: chordates and plants | http://doop.abc.hu/ | |
| 106 | DPInteract | Binding sites for E. coli DNA-binding proteins | http://arep.med.harvard.edu/dpinteract/ | |
| 33 | EPD | Eukaryotic promoter database | http://www.epd.isb-sib.ch/ | |
| 329 | GeneNet | Database on gene network components | http://wwwmgs.bionet.nsc.ru/mgs/gnw/genenet/ | |
| 1036 | GenomeTraFaC | Conserved regulatory elements of human and mouse genes | http://genometrafac.cchmc.org | |
| 823 | HTPSELEX | Transcription factor binding site sequences obtained using high-throughput SELEX method | http://www.isrec.isb-sib.ch/htpselex/ | |
| 516 | JASPAR | PSSMs for transcription factor DNA-binding sites | http://jaspar.cgb.ki.se | |
| 700 | MAPPER | Putative transcription factor binding sites in various genomes | http://bio.chip.org/mapper | |
| 842 | MPromDB | Mammalian promoter database | http://bioinformatics.med.ohio-state.edu/MPromDb | |
| 846 | ODB | Operon database | http://odb.kuicr.kyoto-u.ac.jp/ | |
| 185 | ooTFD | Object-oriented transcription factors database | http://www.ifti.org/ootfd | |
| 1107 | ORegAnno | Open REGulatory ANNOtation database | http://www.oreganno.org/ | |
| 711 | Osteo-Promoter DB | Genes in osteogenic proliferation and differentiation | http://www.opd.tau.ac.il | |
| 40 | PLACE | Plant cis-acting regulatory DNA elements | http://www.dna.affrc.go.jp/PLACE/ | |
| 41 | PlantCARE | Plant promoters and cis-acting regulatory elements | http://bioinformatics.psb.ugent.be/webtools/plantcare/html/ | |
| 563 | PlantProm | Plant promoter sequences for RNA polymerase II | http://mendel.cs.rhul.ac.uk/mendel.php?topic=plantprom | |
| 1117 | PlantTFDB | Plant Transcription Factor Database | http://planttfdb.cbi.pku.edu.cn | |
| 1005 | PReMod | Predicted transcriptional regulatory modules in the human genome | http://genomequebec.mcgill.ca/PReMod | |
| 566 | PRODORIC | Prokaryotic database of gene regulation networks | http://prodoric.tu-bs.de/ | |
| 42 | PromEC | E. coli promoters with experimentally-identified transcriptional start sites | http://margalit.huji.ac.il/promec/ | |
| 1123 | ProTISA | Translation Initiation Site Annotation in prokaryotic genomes | http://mech.ctb.pku.edu.cn/protisa/ | |
| 116 | RegulonDB | Transcriptional regulation and operon organization in E.coli | http://regulondb.ccg.unam.mx/ | |
| 45 | rSNP Guide | SNPs in regulatory gene regions | http://wwwmgs.bionet.nsc.ru/mgs/systems/rsnp/ | |
| 577 | SCPD | Saccharomyces cerevisiae promoter database | http://rulai.cshl.edu/SCPD/ | |
| 246 | SELEXdb | Selected DNA/RNA functional site sequences | http://wwwmgs.bionet.nsc.ru/mgs/systems/selex/ | |
| 1015 | SwissRegulon database | Genome-wide annotations of regulatory sites in the intergenic regions | http://www.swissregulon.unibas.ch | |
| 227 | TESS | Transcription element search system | http://www.cbil.upenn.edu/tess | |
| 904 | TiProD | Tissue-specific promoter database | http://tiprod.cbi.pku.edu.cn:8080/index.html | |
| 756 | Tractor_DB | Transcription factors in gamma-proteobacteria database | http://www.tractor.lncc.br | |
| 345 | TRANSCompel® | Transcriptional regulation, composite regulatory elements | http://www.gene-regulation.com/pub/ databases.html#transcompel | |
| 340 | TRANSFAC® | Transcription factors, gene regulation, positional weight matrices | http://www.gene-regulation.com | |
| 1141 | TransfactomeDB | Nucleotide sequence specificity and condition-specific regulatory activity of trans-acting factors | http://bussemakerlab.org/YeastTransfactomeDB/ | |
| 341 | TRANSPATH | Signal transduction pathways, vizualization and expression data analysis | http://www.biobase.de/pages/products/databases.html | |
| 48 | Transterm | Codon usage, start and stop signals | http://guinevere.otago.ac.nz/transterm.html | |
| 757 | TRED | Transcriptional regulatory element database | http://rulai.cshl.edu/tred | |
| 49 | TRRD | Transcription regulatory regions of eukaryotic genes | http://www.bionet.nsc.ru/trrd/ | |
| 314 | TrSDB | Transcription factor database | http://bioinf.uab.es/cgi-bin/trsdb/trsdb.pl | |
| 792 | YEASTRACT | Yeast transcriptional regulation | http://www.yeastract.com | |
| 2. RNA Sequence, Structure and Functions | ||||
| 229 | 16S and 23S rRNA Mutation Database | 16S and 23S ribosomal RNA mutations | http://ribosome.fandm.edu | |
| 1041 | 3D rRNA modification maps | Locations of modified rRNA nucleotides within the 3D structure of the ribosome | http://people.biochem.umass.edu/fournierlab/3dmodmap/ | |
| 230 | 5S rRNA Database | 5S rRNA sequences | http://biobases.ibch.poznan.pl/5SData/ | |
| 411 | Aptamer Database | Small RNA/DNA molecules binding nucleic acids, proteins | http://aptamer.icmb.utexas.edu | |
| 232 | ARED | AU-rich element-containing mRNAs | http://brp.kfshrc.edu.sa/ARED | |
| 797 | Argonaute | Gene regulation by mammalian microRNAs | http://argonaute.uni-hd.de | |
| 984 | dbRES | Database of known RNA editing sites | http://bioinfo.au.tsinghua.edu.cn/dbRES/ | |
| 463 | European rRNA DB | All complete or nearly complete rRNA sequences | http://www.psb.ugent.be/rRNA/ | |
| 1027 | fRNAdb | Functional RNA Database: noncoding transcripts that affect gene expression | http://www.ncrna.org/ | |
| 878 | Greengenes | Multiple sequence alignment of prokaryotic 16S rDNA | http://greengenes.llnl.gov/16S/ | |
| 820 | GRSDB | G-rich sequences database | http://bioinformatics.ramapo.edu/GRSDB2/ | |
| 490 | G-tRNA-db | Genomic tRNA Database | http://lowelab.ucsc.edu/GtRNAdb/ | |
| 236 | Guide RNA Database | No longer maintained | ||
| 76 | HIV Sequence DB | HIV RNA sequences | http://hiv-web.lanl.gov/ | |
| 689 | HuSiDa | Human siRNA database | http://itb.biologie.hu-berlin.de/~nebulus/sirna/index.htm | |
| 237 | HyPaLib | Hybrid pattern library: structural elements in classes of RNA | Not actively maintained | |
| 379 | IRESdb - | the Internal Ribosome Entry Site database | http://ifr31w3.toulouse.inserm.fr/IRESdatabase/ | |
| 831 | IRESite | Experimentally studied internal ribosome entry sites | http://www.iresite.org | |
| 838 | MeRNA | Metal ion binding sites in RNA | http://merna.lbl.gov | |
| 1097 | microRNA.org | microRNA target predictions and expression profiles | http://www.microrna.org | |
| 529 | miRBase | MicroRNA sequences, names, and predicted targets in animals | http://microrna.sanger.ac.uk/sequences/ | |
| 1098 | miRGator | microRNA target prediction, functional analysis, and gene expression data | http://genome.ewha.ac.kr/miRGator/miRGator.html | |
| 994 | miRGen | Animal microRNAs located in introns, exons, UTRs, pseudogenes and CpG islands | http://www.diana.pcbi.upenn.edu/miRGen | |
| 895 | miRNAMap | microRNA precursors and their mapping to targets in vertebrate genomes | http://mirnamap.mbc.nctu.edu.tw | |
| 378 | Mobile group II introns | Database for mobile group II introns | http://www.fp.ucalgary.ca/group2introns/ | |
| 840 | MODOMICS | Database of RNA modification pathways | http://genesilico.pl/modomics/ | |
| 997 | NATsDB | Natural Antisense Transcripts database | http://nats.cbi.pku.edu.cn | |
| 380 | NCIR | Non-Canonical Interactions in RNA | http://prion.bchs.uh.edu/bp_type/ | |
| 381 | ncRNAs database | Non-coding RNAs with regulatory functions | http://biobases.ibch.poznan.pl/ncRNA/ | |
| 705 | NONCODE | Database of noncoding RNAs | http://bioinfo.ibp.ac.cn/NONCODE/index.htm | |
| 845 | NPInter | Noncoding RNA-protein interactions | http://bioinfo.ibp.ac.cn/NPInter/index.php | |
| 1114 | piRNABank | Sequences and properties of Piwi-interacting RNAs (piRNAs) in human, mouse and rat | http://pirnabank.ibab.ac.in/ | |
| 564 | Plant snoRNA DB | snoRNA genes in plant species | http://bioinf.scri.sari.ac.uk/cgi-bin/plant_snorna/home | |
| 240 | PLANTncRNAs | No longer maintained | ||
| 241 | PLMItRNA | Mitochondrial tRNA genes in photosynthetic eukaryotes | http://bighost.area.ba.cnr.it/PLMItRNA/ | |
| 723 | PolyA_DB | Database of mammalian mRNA polyadenylation | http://polya.umdnj.edu/ | |
| 242 | PseudoBase | Database of RNA pseudoknots | http://wwwbio.leidenuniv.nl/~Batenburg/PKB.html | |
| 1009 | REDIdb | An RNA editing database | http://biologia.unical.it/py_script/search.html | |
| 382 | Rfam | Non-coding RNA families | http://www.sanger.ac.uk/Software/Rfam/ | |
| 243 | RDP-II | Ribosomal Database Project | http://rdp.cme.msu.edu | |
| 244 | RISSC | Ribosomal Internal Spacer Sequence Collection | http://egg.umh.es/rissc | |
| 245 | RNA Modification DB | Naturally modified nucleosides in RNA | http://medlib.med.utah.edu/RNAmods/ | |
| 900 | RNA SSTRAND | RNA secondary structure data and structural motifs | http://www.rnasoft.ca/sstrand | |
| 630 | RNAdb | Mammalian noncoding RNA database | http://ncrna.bioinformatics.com.au | |
| 862 | RNAi codex | Clones from mouse, human and rat shRNA libraries | http://codex.cshl.org | |
| 1162 | siRecords | Experimentally tested mammalian siRNAs | http://sirecords.umn.edu/siRecords/ | |
| 629 | siRNAdb | Functional human siRNA sequences | http://sirna.cgb.ki.se | |
| 247 | Small RNA Database | No longer maintained | ||
| 869 | snoRNA-LBME-db | Human snoRNAs and Cajal body-specific RNAs (scaRNAs) | http://www-snorna.biotoul.fr/ | |
| 962 | Sno/scaRNAbase | Small nucleolar RNAs and cajal body-specific RNAs | http://gene.fudan.sh.cn/snoRNAbase.nsf | |
| 248 | SRPDB | Signal recognition particle database | http://rnp.uthct.edu/rnp/SRPDB/SRPDB.html | |
| 383 | Subviral RNA DB | Database of viroids and viroid-like RNAs | http://subviral.med.uottawa.ca/ | |
| 754 | The Small Subunit rRNA Modification DB | Modified nucleosides in small subunit rRNA | http://library.med.utah.edu/SSUmods/ | |
| 250 | tmRDB | tmRNA database | http://rnp.uthct.edu/rnp/tmRDB/tmRDB.html | |
| 249 | tmRNA Website | tmRNA sequences and alignments | http://www.indiana.edu/~tmrna | |
| 251 | tRNA Sequences | Has not been updated | ||
| 1148 | Vir-Mir db | Prediction of viral microRNA candidate hairpins | http://alk.ibms.sinica.edu.tw | |
| 254 | Yeast snoRNA Database | Yeast small nucleolar RNAs | http://www.bio.umass.edu/biochem/rna-sequence/Yeast_snoRNA_Database/snoRNA_DataBase.html | |
| 3. Protein Sequence Databases | ||||
| 3.1. General sequence databases | ||||
| 163 | EXProt | Sequences of proteins with experimentally verified function | http://www.cmbi.kun.nl/EXProt/ | |
| 88 | MIPS resources | Munich Information Center for Protein Sequences databases | http://mips.gsf.de/ | |
| 542 | NCBI Protein database | All protein sequences: translated from GenBank and imported from other protein databases | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Protein | |
| 714 | PA-GOSUB | Protein sequences from model organisms, GO assignment and subcellular localization | http://www.cs.ualberta.ca/~bioinfo/PA/ | |
| 194 | PIR | Protein Information Resource | http://pir.georgetown.edu | |
| 565 | PRF | Protein research foundation database of peptides | http://www.prf.or.jp/en/index.shtml | |
| 790 | TCDB | Transporter protein classification database | http://www.tcdb.org/ | |
| 775 | UniParc | UniProt archive, a repository of all protein sequences | http://www.uniprot.org/database/archive.shtml | |
| 318 | UniProt | Universal Protein knowledgebase, combined information from Swiss-Prot, TrEMBL, and PIR | http://www.uniprot.org | |
| 197 | UniProtKB\Swiss-Prot | Formerly SwissProt, part of the UniProt knowledgebase | http://www.expasy.org/sprot | |
| 198 | UniProtKB\TrEMBL | Now UniProt/TrEMBL, part of the UniProt knowledgebase | http://www.uniprot.org/database/knowledgebase.shtml | |
| 776 | UniRef | Clustered sets of related sequences from UniProt | http://www.uniprot.org/database/nref.shtml | |
| 1165 | UniSave | UniProtKB Sequence/Annotation Version Archive | http://www.ebi.ac.uk/uniprot/unisave/ | |
| 3.2. Protein properties | ||||
| 221 | AAindex | Physicochemical properties of amino acids | http://www.genome.ad.jp/aaindex/ | |
| 979 | BindingDB | Binding affinities of protein-ligand and other complexes | http://www.bindingdb.org/bind/index.jsp | |
| 806 | CyBase | Proteins with cyclic backbones | http://research1t.imb.uq.edu.au/cybase | |
| 885 | dbPTM | Information on post-translational modification of proteins | http://dbptm.mbc.nctu.edu.tw/ | |
| 914 | iProLINK | Annotated literature sources for protein features and names | http://pir.georgetown.edu/iprolink | |
| 1093 | MALISAM | Manual alignments for structurally analogous motifs in proteins | http://prodata.swmed.edu/malisam | |
| 1094 | MegaMotifbase | Structural motifs in protein families and superfamilies | http://caps.ncbs.res.in/MegaMotifbase/index.html | |
| 954 | PIDD | Protein inter-atomic distances database | http://pidd.math.iastate.edu | |
| 854 | PINT | Protein-protein interactions thermodynamic database | http://pintdb.dyndns.org/index.html | |
| 856 | PPD | Experimentally-determined protein pKa values | http://www.jenner.ac.uk/ppd/ | |
| 1120 | PPT-DB | Protein Property Prediction and Testing Database | http://redpoll.pharmacy.ualberta.ca/PPT_DB/public_html/PPT_main.html | |
| 280 | ProTherm | Thermodynamic data for wild-type and mutant proteins | http://gibk26.bse.kyutech.ac.jp/jouhou/protherm/protherm.html | |
| 1176 | PRTAD | Protein residue torsion angle database | http://www.math.iastate.edu/prtad | |
| 783 | REFOLD | Experimental data on protein refolding and purification | http://refold.med.monash.edu.au | |
| 3.3. Protein localization and targeting | ||||
| 444 | DBSubLoc - | Database of protein Subcellular Localization | http://www.bioinfo.tsinghua.edu.cn/dbsubloc.html | |
| 930 | eSLDB | eukaryotic proteins Subcellular Localization Database | http://gpcr.biocomp.unibo.it/esldb | |
| 1021 | InterFil | Human Intermediate Filament database | http://www.interfil.org | |
| 836 | LOCATE | Subcellular localization of mouse proteins | http://locate.imb.uq.edu.au/ | |
| 1022 | MiCroKit | Midbody, Centrosome and Kinetochore proteins | http://bioinformatics.lcd-ustc.org/microkit/ | |
| 226 | MitoDrome | Nuclear-encoded mitochondrial proteins of Drosophila | http://www2.ba.itb.cnr.it/MitoDrome/ | |
| 85 | MitoRes | Nuclear genes coding for mitochondrial proteins | http://www2.ba.itb.cnr.it/MitoNuc/ | |
| 375 | NESbase | Nuclear export signals database | http://www.cbs.dtu.dk/databases/NESbase | |
| 376 | NLSdb | Nuclear localization signals | http://cubic.bioc.columbia.edu/db/NLSdb/ | |
| 704 | NMPdb | Nuclear matrix associated proteins database | http://www.rostlab.org/db/NMPdb/ | |
| 706 | NOPdb: | Nucleolar proteome database | http://www.lamondlab.com/NOPdb/ | |
| 369 | NPD | Nuclear Protein Database | http://npd.hgu.mrc.ac.uk | |
| 182 | Nuclear Receptor Resource | Nuclear receptor superfamily | http://nrr.georgetown.edu/NRR/nrrhome.htm | |
| 183 | NUREBASE | Nuclear hormone receptors database | http://www.ens-lyon.fr/LBMC/laudet/nurebase/nurebase.html | |
| 789 | NURSA | Nuclear receptor signaling atlas | http://www.nursa.org | |
| 734 | PSORTdb | Protein subcellular localization in bacteria | http://db.psort.org/ | |
| 745 | Secreted Protein DB | Secreted proteins from human, mouse and rat | http://spd.cbi.pku.edu.cn | |
| 1014 | SUBA | Subcellular localisation of Arabidopsis proteins | http://www.suba.bcs.uwa.edu.au/ | |
| 587 | THGS | Transmembrane Helices in Genome Sequences | http://pranag.physics.iisc.ernet.in/thgs/ | |
| 1140 | TopDB | Topology Data Bank of transmembrane proteins | http://topdb.enzim.hu | |
| 589 | Transmembrane Protein Database | Transmembrane proteins with experimentally-characterized transmembrane topologies | http://bioinfo.si.hirosaki-u.ac.jp/~TMPDB/ | |
| 3.4. Protein sequence motifs and active sites | ||||
| 374 | ASC | Active Sequence Collection | http://bioinformatica.isa.cnr.it/ASC/ | |
| 203 | Blocks | Alignments of conserved regions in protein families | http://blocks.fhcrc.org | |
| 438 | COMe | Co-Ordination of Metals etc. | http://www.ebi.ac.uk/come/ | |
| 771 | CoPS | Comprehensive peptide signature database | http://cops.igib.res.in/copsv2/index.html | |
| 440 | CSA | Catalytic Site Atlas | http://www.ebi.ac.uk/thornton-srv/databases/CSA/ | |
| 666 | eBLOCKS | Highly conserved protein sequence blocks | http://fold.stanford.edu/eblocks/acsearch.html | |
| 452 | eF-site | Electrostatic surface of Functional site | http://ef-site.protein.osaka-u.ac.jp/eF-site | |
| 206 | eMOTIF | Protein sequence motif determination and searches | http://motif.stanford.edu/emotif | |
| 986 | FireDB | Functionally important residues in protein structures | http://firedb.bioinfo.cnio.es/ | |
| 207 | InterPro | Integrated resource of protein families, domains and functional sites | http://www.ebi.ac.uk/interpro | |
| 179 | Metalloprotein Site DB | Metal-binding sites in metalloproteins | http://metallo.scripps.edu/ | |
| 209 | O-GLYCBASE | O- and C-linked glycosylation sites in proteins | http://www.cbs.dtu.dk/databases/OGLYCBASE/ | |
| 717 | PDBSite | 3D structure of protein functional sites | http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-page+LibInfo+-newId+-lib+PDBSite | |
| 187 | Phospho.ELM | S/T/Y protein phosphorylation sites (former PhosphoBase) | http://phospho.elm.eu.org/ | |
| 1003 | Phospho3D | 3D structures of protein phosphorylation sites | http://cbm.bio.uniroma2.it/p3d/ | |
| 212 | PRINTS | Hierarchical gene family fingerprints | http://umber.sbs.man.ac.uk/dbbrowser/PRINTS/ | |
| 193 | PROMISE | Prosthetic centers and metal ions in protein active sites | http://metallo.scripps.edu/PROMISE/ | |
| 899 | ProRule | Functional and structural information on PROSITE profiles | http://www.expasy.org/prosite/prorule.html | |
| 215 | PROSITE | Biologically-significant protein patterns and profiles | http://www.expasy.org/prosite | |
| 732 | ProTeus | Signature sequences at the protein N- and C-termini | http://www.proteus.cs.huji.ac.il | |
| 868 | SitesBase | Known ligand binding sites in the PDB | http://www.modelling.leeds.ac.uk/sb/ | |
| 3.5. Protein domain databases; protein classification | ||||
| 622 | ADDA | Database of protein domain classification | http://ekhidna.biocenter.helsinki.fi/sqgraph/pairsdb | |
| 288 | BAliBASE | Benchmark database for comparison of multiple sequence alignments | http://www-igbmc.u-strasbg.fr/BioInfo/BAliBASE2/index.html | |
| 978 | Benchmark | Protein classification benchmark collection: training/test sets for machine learning | http://net.icgeb.org/benchmark/ | |
| 786 | BIOZON | Database of gene and protein familiy classification | http://biozon.org | |
| 204 | CDD | Conserved domain database, includes protein domains from Pfam, SMART, COG and KOG databases | http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml | |
| 205 | CluSTr | Clusters of UniProt Knowledgebase and IPI proteins | http://www.ebi.ac.uk/clustr/ | |
| 7 | COG | Clusters of orthologous groups of proteins | http://www.ncbi.nlm.nih.gov/COG | |
| 448 | DomIns | Database of Domain Insertions | http://www.domins.org/ | |
| 1068 | eggNOG | Evolutionary genealogy of genes: Non-supervised Orthologous Groups | http://eggnog.embl.de | |
| 1069 | EPGD | Eukaryotic Paralog Group Database | http://epgd.biosino.org:8080/EPGD/ | |
| 963 | EVEREST | Automatically generated protein domain families | http://www.everest.cs.huji.ac.il | |
| 671 | FunShift | Functional divergence between the subfamilies of a protein domain family | http://FunShift.cgb.ki.se | |
| 470 | FusionDB | Database of bacterial and archaeal gene fusion events | http://www.igs.cnrs-mrs.fr/FusionDB/ | |
| 200 | Hits | Database of protein domains and motifs | http://hits.isb-sib.ch | |
| 266 | HSSP | Homology-derived structures of proteins | http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-page+LibInfo+-lib+HSSP | |
| 510 | InterDom | Putative protein domain interactions | http://interdom.i2r.a-star.edu.sg/ | |
| 208 | iProClass | Integrated protein classification database | http://pir.georgetown.edu/iproclass/ | |
| 844 | MulPSSM | Multiple PSSMs of structural and sequence families | http://hodgkin.mbu.iisc.ernet.in/~mulpssm | |
| 1109 | PairsDB | Pairwise alignments of all sequences in UniProt | http://pairsdb.csc.fi | |
| 274 | PALI | Phylogeny and alignment of homologous protein structures | http://pauling.mbu.iisc.ernet.in/~pali | |
| 552 | PANTHER | Protein sequence evolution mapped to functions and pathways | http://www.pantherdb.org | |
| 210 | Pfam | Protein families: Multiple sequence alignments and profile hidden Markov models of protein domains | http://pfam.sanger.ac.uk/ | |
| 981 | PhyloFacts | Phylogenomic analysis of protein families | http://phylogenomics.berkeley.edu/phylofacts/ | |
| 561 | PIRSF | Family/superfamily classification of whole proteins | http://pir.georgetown.edu/pirsf/ | |
| 214 | ProDom | Protein domain families | http://prodom.prabi.fr/ | |
| 216 | ProtoMap | Hierarchical classification of Swiss-Prot proteins | http://protomap.cornell.edu | |
| 567 | ProtoNet | Hierarchical clustering of Swiss-Prot proteins | http://www.protonet.cs.huji.ac.il/ | |
| 217 | SBASE | Protein domain sequences and tools | http://www.icgeb.org/sbase | |
| 867 | SIMAP | Similarity matrix of proteins: precomputed similarity data | http://mips.gsf.de/simap/ | |
| 1010 | SISYPHUS | Structural alignments for proteins with non-trivial relationships | http://sisyphus.mrc-cpe.cam.ac.uk | |
| 218 | SMART | Simple modular architecture research tool: signalling, extracellular and chromatin-associated protein domains | http://smart.embl-heidelberg.de | |
| 219 | SUPFAM | Grouping of sequence families into superfamilies | http://pauling.mbu.iisc.ernet.in/~supfam | |
| 199 | TIGRFAMs | TIGR protein families adapted for functional annotation | http://www.tigr.org/TIGRFAMs | |
| 3.6. Databases of individual protein families | ||||
| 157 | ABCdb | Archaeal and bacterial ABC transporter database | http://www-abcdb.biotoul.fr | |
| 156 | Aminoacyl-tRNA synthetases database | Aminoacyl-tRNA synthetase database | http://rose.man.poznan.pl/aars/index.html | |
| 1045 | Animal Toxin DB | Database of animal toxins | http://protchem.hunnu.edu.cn/toxin | |
| 412 | ARAMEMNON | Arabidopsis thaliana membrane proteins and transporters | http://aramemnon.botanik.uni-koeln.de | |
| 1166 | BACTIBASE | Database of bacteriocin natural antimicrobial peptides | http://www.pfba-lab.org/bactibase | |
| 158 | BacTregulators | Transcriptional regulators of AraC and TetR families | No longer maintained | |
| 976 | BANMOKI | Database of bacterial nucleoside monophosphate kinases | http://www.ces.clemson.edu/compbio/databases/kinases | |
| 1057 | ChromDB | Chromatin-associated proteins in a broad range of organisms | http://www.chromdb.org | |
| 923 | cpnDB | Chaperonin database | http://cpndb.cbr.nrc.ca/ | |
| 1154 | CREMOFAC | Database of chromatin remodeling factors | http://www.jncasr.ac.in/cremofac/ | |
| 364 | CSDBase | Cold Shock Domain database | http://www.chemie.uni-marburg.de/~csdbase/ | |
| 1168 | CyMoBase | Cytoskeletal and motor proteins database | http://www.motorprotein.de/cymobase | |
| 1065 | DB-PABP | Experimentally characterized polyanion-binding proteins | http://ppa.bcf.ku.edu/DB_PABP/ | |
| 658 | DCCP | Database of Copper-Chelating Proteins | http://sdbi.sdut.edu.cn/DCCP/en/index.php | |
| 945 | Defensins Knowledgebase | Antimicrobial peptides of the defensin family | http://defensins.bii.a-star.edu.sg/ | |
| 160 | DExH/D Family DB | DEAD-box, DEAH-box and DExH-box proteins | http://www.helicase.net/dexhd/dbhome.htm | |
| 892 | DSD | Database of dehydrogenase stereospecificities | http://www.jenner.ac.uk/DSD | |
| 161 | Endogenous GPCR List | G protein-coupled receptors; expression in cell lines | http://www.tumor-gene.org/GPCR/gpcr.html | |
| 814 | EROP-Moscow | Database of Endogenous Regulatory OligoPeptides | http://erop.inbi.ras.ru | |
| 162 | ESTHER | Esterases and other alpha/beta hydrolase enzymes | http://bioweb.ensam.inra.fr/ESTHER/general?what=index | |
| 164 | FUNPEP | Low-complexity peptides capable of forming amyloid plaque | http://www.cmbi.kun.nl/swift/FUNPEP/gergo/ | |
| 166 | GPCRDB | G protein-coupled receptors database | http://www.gpcr.org/7tm/ | |
| 679 | gpDB | G-protein database: G-proteins and their interaction with GPCRs | http://bioinformatics.biol.uoa.gr/gpDB | |
| 1085 | Heme Protein DB | Heme protein structure, heme type, axial ligands, and heme protein reduction potential (Em) values | http://heme.chem.columbia.edu/heme.php | |
| 167 | Histone Database | Histone fold sequences and structures | http://research.nhgri.nih.gov/histones/ | |
| 365 | HIV RT and Protease Sequence Database | HIV reverse transcriptase and protease sequences | http://hivdb.stanford.edu | |
| 169 | Homeobox Page | Homeobox proteins, classification, and evolution | http://www.biosci.ki.se/groups/tbu/homeo.html | |
| 170 | Homeodomain Resource | Homeodomain sequences, structures, and related genetic and genomic information | http://research.nhgri.nih.gov/homeodomain/ | |
| 174 | InBase | Inteins (protein splicing elements) database: properties, sequences, bibliography | http://www.neb.com/neb/inteins.html | |
| 518 | KinG | Kinases in Genomes: Ser/Thr/Tyr kinases encoded in the completely sequenced genomes | http://hodgkin.mbu.iisc.ernet.in/~king | |
| 519 | Knottin database | Database of knottins, small proteins with an unusual "disulfide through disulfide" knot | http://knottin.cbs.cnrs.fr/ | |
| 176 | LGICdb | Ligand-gated ion channel subunit sequences database | http://www.pasteur.fr/recherche/banques/LGIC/LGIC.html | |
| 368 | Lipase Engineering DB | Sequence, structure and function of lipases and esterases | http://www.led.uni-stuttgart.de/ | |
| 524 | LOX-DB | Mammalian, invertebrate, plant and fungal lipoxygenases | http://www.dkfz-heidelberg.de/spec/lox-db/ | |
| 177 | MEROPS | Database of proteolytic enzymes (peptidases) | http://merops.sanger.ac.uk/ | |
| 1105 | NORINE | Database of nonribosomal peptides | http://bioinfo.lifl.fr/norine/ | |
| 546 | NucleaRDB | Nuclear receptor superfamily | http://www.receptors.org/NR/ | |
| 184 | Olfactory Receptor DB | Sequences for olfactory receptor-like molecules | http://senselab.med.yale.edu/senselab/ordb/ | |
| 186 | Peptaibol | Peptaibol (antibiotic peptide) sequences | http://www.cryst.bbk.ac.uk/peptaibol/ | |
| 560 | PhytoProt | Clusters of (predicted) plant proteins | http://urgi.versailles.inra.fr/phytoprot/ | |
| 189 | PLANT-PIs | Plant protease inhibitors | http://bighost.area.ba.cnr.it/PLANT-Pis | |
| 371 | PlantsP/PlantsT | Plant proteins involved in phosphorylation and transport | http://plantsp.sdsc.edu | |
| 759 | PLPMDB | Pyridoxal-5'-phosphate dependent enzymes mutations | http://www.studiofmp.com/plpmdb/ | |
| 609 | ProLysED | Database of bacterial protease systems | http://genome.ukm.my/prolyses/ | |
| 192 | Prolysis | Proteases and natural and synthetic protease inhibitors | http://delphi.phys.univ-tours.fr/Prolysis/ | |
| 188 | Protein kinase resource | Protein kinase resource: sequences, enzymology, genetics and molecular and structural properties | http://www.kinasenet.org/pkr/ | |
| 224 | REBASE | Restriction enzymes and associated methylases | http://rebase.neb.com/rebase/rebase.html | |
| 195 | RNAse P Database | Ribonuclease P sequences, alignments and structures | http://www.mbio.ncsu.edu/RNaseP/home.html | |
| 901 | RNRdb | Ribonucleotide reductase database | http://rnrdb.molbio.su.se/ | |
| 573 | RPG | Ribosomal Protein Gene database | http://ribosome.miyazaki-med.ac.jp/ | |
| 575 | RTKdb | Receptor Tyrosine Kinase database | http://pbil.univ-lyon1.fr/RTKdb/ | |
| 372 | SDAP | Structural database of allergenic proteins and food allergens | http://fermi.utmb.edu/SDAP | |
| 1131 | SelenoDB | Database of selenoprotein genes, proteins and SECIS elements | http://www.selenodb.org/ | |
| 196 | SENTRA | Sensory signal transduction proteins | http://compbio.mcs.anl.gov/sentra/ | |
| 373 | SEVENS | 7-transmembrane helix receptors (G-protein-coupled) | http://sevens.cbrc.jp/1.20/ | |
| 1137 | Telomerase database | Sequences and structures of the RNA and protein subunits of telomerase, mutations of telomerase components | http://telomerase.asu.edu | |
| 311 | TransportDB | Predicted membrane transporters in complete genomes, classified according to the TC classification system | http://www.membranetransport.org | |
| 399 | VKCDB | Voltage-gated K+ Channel Database | http://vkcdb.biology.ualberta.ca/ | |
| 202 | Wnt Database | Wnt proteins and phenotypes | http://www.stanford.edu/~rnusse/wntwindow.html | |
| 4. Structure Databases | ||||
| 4.1. Small molecules | ||||
| 402 | AANT | Amino Acid - Nucleotide interaction database | http://aant.icmb.utexas.edu/ | |
| 646 | ChEBI | Chemical entities of biological interest | http://www.ebi.ac.uk/chebi/ | |
| 1024 | ChemBank | Structures and biological activities of small organic molecules | http://chembank.broad.harvard.edu/ | |
| 1023 | ChemDB | 3D structures and properties of small molecules | http://cdb.ics.uci.edu | |
| 261 | CSD | Cambridge Structural Database | http://www.ccdc.cam.ac.uk/prods/csd/csd.html | |
| 360 | Het-PDB Navi | Hetero-atoms in protein structures | http://daisy.bio.nagoya-u.ac.jp/golab/hetpdbnavi.html | |
| 265 | HIC-Up | Hetero-compound Information Centre - Uppsala | http://xray.bmc.uu.se/hicup/ | |
| 111 | Klotho | Collection and categorization of biological compounds | http://www.biocheminfo.org/klotho/ | |
| 113 | LIGAND | Chemical compounds and reactions in biological pathways | http://www.genome.ad.jp/ligand/ | |
| 615 | PDB-Ligand | 3D structures of small molecules bound to proteins and nucleic acids | http://www.idrtech.com/PDB-Ligand/ | |
| 735 | PubChem | Structures and biological activities of small organic molecules | http://pubchem.ncbi.nlm.nih.gov/ | |
| 1127 | R.E.DD.B. | RESP and ESP atomic charges and force field libraries for small molecules and molecular fragments | http://q4md-forcefieldtools.org/REDDB | |
| 4.2. Carbohydrates | ||||
| 977 | BCSDB/Glycoscience | Bacterial Carbohydrate Structure DataBase | http://www.glyco.ac.ru/bcsdb/start.shtml | |
| 429 | CarbBank | CCSD - Complex Carbohydrate Structure Database | http://bssv01.lancs.ac.uk/gig/pages/gag/carbbank.htm | |
| 652 | CSS | Carbohydrate Structure Suite: carbohydrate 3D structures | http://www.dkfz.de/spec/css/ | |
| 486 | Glycan | Carbohydrate database, part of the KEGG system | http://glycan.genome.ad.jp/ | |
| 1080 | Glycoconjugate Data Bank | Annotated structures of glycan molecules | http://daisy2.nagahama-i-bio.ac.jp/structures/ | |
| 988 | GlycoMaps DB | Conformational maps of disaccharides | http://www.glycosciences.de/modeling/glycomapsdb/ | |
| 292 | GlycoSuiteDB | N- and O-linked glycan structures and biological sources | http://www.glycosuite.com | |
| 535 | Monosaccharide Browser | Space filling Fischer projections of monosaccharides | http://www.terravivida.com/vivida/monosaccharide/ | |
| 300 | SWEET-DB | Annotated carbohydrate structure and substance information | http://www.dkfz-heidelberg.de/spec2/sweetdb/ | |
| 4.3. Nucleic acid structure | ||||
| 1082 | Greglist | G-quadruplex motifs and potentially G-quadruplex regulated genes | http://tubic.tju.edu.cn/greglist/ | |
| 1090 | ITS2 | Predicted structures of internal transcribed spacer 2 (ITS2) molecules | http://its2.bioapps.biozentrum.uni-wuerzburg.de/ITS2_db.html | |
| 272 | NDB | Nucleic acid-containing structures | http://ndbserver.rutgers.edu/ | |
| 273 | NTDB | Thermodynamic data for nucleic acids | http://ntdb.chem.cuhk.edu.hk | |
| 1126 | QuadBase | G-quadruplex motifs in the promoters of human, chimpanzee, rat, mouse and bacterial genes | http://quadbase.igib.res.in/ | |
| 1129 | RNA FRABASE | Database of 3D RNA fragments within known RNA structures | http://rnafrabase.ibch.poznan.pl/ | |
| 387 | RNABase | RNA-containing structures from PDB and NDB | http://www.rnabase.org | |
| 1130 | RNAJunction | RNA structural elements: helical junctions, internal loops, bulges and loop-loop interactions | http://rnajunction.abcc.ncifcrf.gov | |
| 908 | SARS-CoV RNA SSS | Predicted secondary structures of SARS coronavirus RNA | http://www.liuweibo.com/sarsdb/ | |
| 283 | SCOR | Structural classification of RNA: RNA motifs by structure, function and tertiary interactions | http://scor.lbl.gov | |
| 4.4. Protein structure | ||||
| 401 | 3D-Genomics | Structural annotations for complete proteomes | http://www.sbg.bio.ic.ac.uk/3dgenomics | |
| 633 | 3DID | 3D interacting domains | http://gatealoy.pcb.ub.es/3did/ | |
| 413 | ArchDB | Automated classification of protein loop structures | http://gurion.imim.es/archdb | |
| 255 | ASTRAL | Sequences of domains of known structure, selected subsets and sequence-structure correspondences | http://astral.berkeley.edu/ | |
| 1047 | AutoPSI | Automated structural classification of protein sequences | http://www.bio.ifi.lmu.de/AutoPSIDB | |
| 257 | BioMagResBank | NMR spectroscopic data from proteins, peptides, and nucleic acids | http://www.bmrb.wisc.edu/ | |
| 384 | CADB | Conformational Angles DataBase of Proteins | http://cluster.physics.iisc.ernet.in/cadb/ | |
| 258 | CATH | Protein domain structures database | http://www.cathdb.info/ | |
| 259 | CE | Combinatorial Extension method to compute and review 3D protein structure alignments | http://cl.sdsc.edu/ce.html | |
| 260 | CKAAPs DB | Conserved Key Amino Acid Positions Database | No longer maintained | |
| 882 | CoC Central | Universally conserved residues in protein folds | http://kulibin.mit.edu/coc/ | |
| 1059 | ColiSNP | Mapping non-synonymous SNPs on protein structures | http://yayoi.kansai.jaea.go.jp/colisnp | |
| 883 | Columba | Annotation of protein structures from the PDB | http://www.columba-db.de | |
| 442 | Dali database | Fold classification based on structural alignment of proteins | http://ekhidna.biocenter.helsinki.fi/dali/start | |
| 1169 | DBAli | Database of structure alignments | http://salilab.org/DBAli/ | |
| 385 | Decoys-R-Us | Computer-generated protein conformations based on sequence data | http://dd.compbio.washington.edu/ | |
| 447 | DisProt | Database of Protein Disorder | http://divac.ist.temple.edu/disprot | |
| 809 | DMAPS | Database of multiple alignments for protein structures | http://bioinformatics.albany.edu/~dmaps | |
| 264 | DSDBASE | Disulfide Database | http://www.ncbs.res.in/~faculty/mini/dsdbase/dsdbase.html | |
| 386 | DSMM | A Database of Simulated Molecular Motions | http://projects.villa-bosch.de/dbase/dsmm/ | |
| 456 | E-MSD | EBI-Macromolecular Structure Database | http://www.ebi.ac.uk/msd | |
| 818 | FSN | Flexible structural neighborhood, structural neighbors of proteins identified by FATCAT tool | http://fatcat.ljcrf.edu/fatcat-cgi/cgi/struct_neibor/fatcatStructNeibor.pl | |
| 469 | FSSP | Superseded by the Dali database, no. 442 | ||
| 472 | Gene3D | Precalculated structural assignments for whole genomes | http://cathwww.biochem.ucl.ac.uk:8080/Gene3D/ | |
| 489 | Genomic Threading DB | Structural annotations of complete genomes | http://bioinf.cs.ucl.ac.uk/GTD | |
| 322 | GTOP | Protein fold predictions from genome sequences | http://spock.genes.nig.ac.jp/~genome/gtop.html | |
| 498 | HOMSTRAD | Homologous structure alignment database: curated structure-based alignments for protein families | http://www-cryst.bioc.cam.ac.uk/homstrad | |
| 267 | IMB Jena Image Library | Visualization and analysis of 3D biopolymer structures | http://www.imb-jena.de/IMAGE.html | |
| 502 | IMGT/3Dstructure-DB | 3D structures of Immunoglobulins, T cell receptors, and MHC proteins | http://imgt3d.igh.cnrs.fr/ | |
| 829 | IMOTdb | Spatially interacting motifs in proteins | http://caps.ncbs.res.in/imotdb/ | |
| 269 | LPFC | Library of protein family core structures | http://helix-web.stanford.edu/LPFC/ | |
| 270 | MMDB | All experimentally-determined 3D structures, linked to NCBI Entrez | http://www.ncbi.nlm.nih.gov/Structure/ | |
| 331 | ModBase | Annotated comparative protein structure models | http://salilab.org/modbase | |
| 262 | MolMovDB | Database of Macromolecular Movements | http://bioinfo.mbb.yale.edu/MolMovDB/ | |
| 107 | MPID | MHC-Peptide Interaction Database | http://surya.bic.nus.edu.sg/mpidt | |
| 275 | PASS2 | Structural motifs of protein superfamilies | http://www.ncbs.res.in/~faculty/mini/campass/pass2.html | |
| 276 | PDB | Protein Data Bank: all known protein structures | http://www.pdb.org/ | |
| 619 | PDB_TM | Transmembrane proteins with known 3D structure | http://pdbtm.enzim.hu/ | |
| 277 | PDB-REPRDB | Representative protein chains, based on PDB entries | http://mbs.cbrc.jp/pdbreprdb-cgi/reprdb_menu.pl | |
| 278 | PDBsum | Summaries and analyses of PDB structures | http://www.ebi.ac.uk/thornton-srv/databases/pdbsum/ | |
| 557 | PepConfDB | Database of peptide conformations | http://www.peptidome.org/products/list.htm | |
| 719 | PFD | Protein Folding Database : Experimental data on protein folding | http://www.foldeomics.org/pfd/public_html/index.php | |
| 855 | PMDB | 3D protein models obtained from structure predictions | http://www.caspur.it/PMDB/ | |
| 281 | RESID | Post-translational modifications of proteins | http://www.ebi.ac.uk/RESID/ | |
| 740 | S4 | Structure-based Sequence Alignments of SCOP Superfamilies | http://compbio.mds.qmw.ac.uk/~james/S4.shtml | |
| 282 | SCOP | Structural classification of proteins | http://scop.mrc-lmb.cam.ac.uk/scop | |
| 863 | SCOPPI | Structural classification of protein-protein interfaces | http://www.scoppi.org | |
| 284 | SLoop | Classification of protein loops | http://www-cryst.bioc.cam.ac.uk/~sloop/ | |
| 530 | SSToSS | Sequence-Structural Templates of Single-member Superfamilies | http://caps.ncbs.res.in/SSTOSS/index.htm | |
| 785 | STING Report | Amino acid properties in proteins of known structure | http://sms.cbi.cnptia.embrapa.br/SMS/STINGm/SMSReport/ | |
| 583 | Structure Superposition Database | Pairwise superpositions of 115 TIM-barrel structures | http://ssd.rbvi.ucsf.edu/ | |
| 285 | SUPERFAMILY | Assignments of proteins to structural superfamilies | http://supfam.org/SUPERFAMILY/ | |
| 584 | SURFACE | Surface residues and functions annotated, compared and evaluated: a database of protein surface patches | http://cbm.bio.uniroma2.it/surface | |
| 585 | SWISS-MODEL Repository | 3D protein structure models generated by automated homology modeling using SWISS-MODEL | http://swissmodel.expasy.org/repository | |
| 764 | TargetDB | Target data from worldwide structural genomics projects | http://targetdb.pdb.org/ | |
| 938 | TMBETA-GENOME | Beta-barrel membrane proteins encoded in various genomes | http://tmbeta-genome.cbrc.jp/annotation/ | |
| 941 | TOPOFIT-DB | Protein structural alignments based on the TOPOFIT method | http://mozart.bio.neu.edu/topofit/ | |
| 310 | TOPS | Topology Of Protein Structures | http://www.tops.leeds.ac.uk | |
| 5. Genomics Databases (non-human) | ||||
| 5.1. Genome annotation terms, ontologies and nomenclature | ||||
| 915 | BioThesaurus | A collection of gene/protein names and associated sequences | http://pir.georgetown.edu/iprolink/biothesaurus | |
| 1075 | FunSimMat | Gene Ontology-based functional similarity values for proteins and protein families | http://gotax.bioinf.mpi-inf.mpg.de/funsimmat/ | |
| 487 | GO | Gene ontology consortium database | http://www.geneontology.org/ | |
| 389 | GOA | Gene Ontology Annotation | http://www.ebi.ac.uk/GOA | |
| 939 | GOPaD | Gene Ontology Partition Database | http://bcl.med.harvard.edu/proj/gopart | |
| 73 | HGNC Database | The HUGO Gene Nomenclature Database (formerly Genew) | http://www.genenames.org/ | |
| 513 | IUBMB Nomenclature database | Nomenclature of enzymes, membrane transporters, electron transport proteins and other proteins | http://www.chem.qmul.ac.uk/iubmb/ | |
| 514 | IUPAC Nomenclature database | Nomenclature of biochemical and organic compounds approved by the IUBMB-IUPAC Joint Commission | http://www.chem.qmul.ac.uk/iupac/ | |
| 515 | IUPHAR-RD | International Union of Pharmacology recommendations on receptor nomenclature and drug classification | http://www.iuphar-db.org/iuphar-rd/ | |
| 926 | Plant Ontology DB | Controlled vocabulary of plant structures and growth stages | http://www.plantontology.org | |
| 358 | SOURCE | Functional genomics resource for human, mouse and rat | http://source.stanford.edu | |
| 906 | TreeBase | Phylogenetic trees and the data matrices used to generate them | http://www.treebase.org/ | |
| 317 | UMLS | Unified medical language system | Requires user registration | |
| 5.2. Taxonomy and identification | ||||
| 1018 | GeneTrees | Pre-compiled alignments and gene phylogenies for a variety of taxonomic groups | http://genetrees.vbi.vt.edu | |
| 78 | ICB | gyrB database for identification of bacteria | http://seasquirt.mbio.co.jp/icb/ | |
| 1088 | IDBD | Infectious Disease Biomarker Database | http://biomarker.korea.ac.kr | |
| 297 | NCBI Taxonomy Browser | Names of all organisms that are represented in GenBank | http://www.ncbi.nlm.nih.gov/Taxonomy/taxonomyhome.html | |
| 299 | RIDOM | Ribosomal Differentiation of Medical Microorganisms | http://www.ridom.de/ | |
| 1135 | SuperCAT | Database for multilocus sequence typing analysis of the Bacillus cereus group of bacteria | http://mlstoslo.uio.no/ | |
| 301 | Tree of Life | Information on phylogeny and biodiversity | http://phylogeny.arizona.edu/tree/phylogeny.html | |
| 965 | VNTR Locus DB | Bacterial Variable Number Tandem Repeat locus database | http://vntr.csie.ntu.edu.tw/ | |
| 5.3. General genomics databases | ||||
| 641 | BacMap | Picture atlas of annotated bacterial genomes | http://wishart.biology.ualberta.ca/BacMap/ | |
| 650 | CoGenT++ | Complete genome tracking: Predicted peptides from fully sequenced genomes | http://cgg.ebi.ac.uk/cgg/cpp_sitemap.html | |
| 445 | DEG | Database of Essential Genes | http://tubic.tju.edu.cn/deg | |
| 1172 | diArk | Database of eukaryotic sequencing projects | http://www.diark.org/diark/ | |
| 451 | EBI Genomes | EBI’s collection of databases for the analysis of complete and unfinished viral, pro- and eukaryotic genomes | http://www.ebi.ac.uk/genomes | |
| 458 | Entrez Genomes | NCBI’s collection of databases for the analysis of complete and unfinished viral, pro- and eukaryotic genomes | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Genome | |
| 461 | ERGO-Light | Integrated biochemical data on 10 bacterial genomes: Publicly-available portion of the ERGO database | http://www.ergo-light.com/ | |
| 674 | GenDiS | Genomic distribution of protein structural superfamilies | http://caps.ncbs.res.in/gendis/home.html | |
| 327 | GeneNest | Gene indices of human, mouse, zebrafish, etc. | http://genenest.molgen.mpg.de/ | |
| 1077 | GenoList | An integrated environment for comparative analysis of microbial genomes | http://genolist.pasteur.fr/ | |
| 484 | Genome Information Broker | DDBJ’s collection of genome databases | http://gib.genes.nig.ac.jp | |
| 678 | Genome Reviews | Integrated view of complete genomes | http://www.ebi.ac.uk/GenomeReviews/ | |
| 916 | Genome Project DB | NCBI's database of large-scale genome sequencing projects | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=genomeprj | |
| 75 | GOLD | Genomes online database: a listing of completed and ongoing genome projects | http://www.genomesonline.org/ | |
| 830 | HOINVGEN | Homologous invertebrate genes | http://pbil.univ-lyon1.fr/databases/hoinvgen/HOINVGEN.html | |
| 690 | Inparanoid | Database of eukaryotic orthologs | http://inparanoid.cgb.ki.se/ | |
| 223 | Integr8 | Functional classification of proteins in whole genomes | http://www.ebi.ac.uk/integr8/ | |
| 777 | KaryotypeDB | Karyotype and chromosome data for animal and plant species | http://www.nenno.it/karyotypedb/ | |
| 112 | KEGG | Kyoto Encyclopedia of Genes and Genomes: databases on genes, proteins, and metabolic pathways | http://www.genome.ad.jp/kegg | |
| 528 | MBGD | Microbial genome database for comparative analysis | http://mbgd.genome.ad.jp/ | |
| 114 | MetaCyc | Metabolic pathways and enzymes from various organisms | http://metacyc.org/ | |
| 1103 | Narcisse | Conserved syntenies for various animal, plant and bacterial genomes | http://narcisse.toulouse.inra.fr | |
| 703 | NegProt | Negative Proteome: A tool for comparison of complete proteomes | http://superfly.ucsd.edu/negprot | |
| 1040 | NMPDR | Database for functional annotation and comparative analysis of microbial genomes | http://www.nmpdr.org | |
| 1106 | OPTIC | Orthologous and Paralogous Transcripts in Clades | http://genserv.anat.ox.ac.uk/ | |
| 549 | ORFanage | Orphan ORFs (ORFs with no homologs) in microbial genomes | No longer maintained | |
| 1108 | OrthoDB | An hierarchical catalog of orthologous proteins in metazoa | http://cegg.unige.ch/orthodb/browse | |
| 847 | OrthoMCL | Orthologous protein clusters from multiple genomes | http://orthomcl.cbil.upenn.edu | |
| 715 | PartiGeneDB | Assembled partial genomes for ~250 eukaryotic organisms | http://www.partigenedb.org/ | |
| 354 | PEDANT | Results of an automated analysis of genomic sequences | http://pedant.gsf.de | |
| 377 | PEP | Predictions for Entire Proteomes | http://cubic.bioc.columbia.edu/pep/ | |
| 1113 | PhylomeDB | Experimentally validated and predicted serine phosphorylation sites in Arabidopsis thaliana | http://phylomedb.bioinfo.cipf.es | |
| 118 | PUMA2 | Metabolic analysis of complete microbial genomes | http://compbio.mcs.anl.gov/puma2/ | |
| 582 | STRING | Predicted functional associations between proteins | http://string.embl.de/ | |
| 66 | TIGR Comprehensive Microbial Resource | Various data on complete microbial genomes: Uniform annotation, properties of DNA and predicted proteins | http://www.tigr.org/tigr-scripts/CMR2/CMRHomePage.spl | |
| 5 | TIGR Gene Indices | Organism-specific databases of EST and gene sequences | http://www.tigr.org/tdb/tgi.shtml | |
| 99 | TIGR Microbial DB | A list of microbial genome sequencing projects | No longer maintained | |
| 877 | VBI Microbial Database | Virginia Bioinformatics Institute microbial database | http://phytophthora.vbi.vt.edu | |
| 5.4. Viral genome databases | ||||
| 1051 | BioHealthBase | Host-pathogen interactions of influenza virus | http://dev.biohealthbase.org/GSearch/PrototypeIndex.jsp | |
| 1061 | CoVDB | Database of coronavirus genes and genomes | http://covdb.microbiology.hku.hk | |
| 810 | DPVweb | Descriptions of plant viruses | http://www.dpvweb.net | |
| 1034 | euHCVdb | European Hepatitis C Virus database | http://euhcvdb.ibcp.fr | |
| 492 | HCV Database | Hepatitis C Virus (HCV) Sequence Database | http://hcv.lanl.gov/ | |
| 473 | HCVdb | Hepatitis C Virus Database | http://hepatitis.ibcp.fr/ | |
| 972 | HepSeq | Epidemiological, clinical, and sequence data on the Hepatitis B virus | http://www.hpa-bioinfodatabases.org.uk/ hepatitis_open/main.php | |
| 495 | HERVd | Human Endogenous Retrovirus database | http://herv.img.cas.cz | |
| 497 | HIV Drug Resistance Database | HIV mutations that confer resistance to anti-HIV drugs | http://resdb.lanl.gov/Resist_DB/default.htm | |
| 168 | HIV Molecular Immunology Database | HIV epitopes | http://hiv-web.lanl.gov/immunology/ | |
| 990 | HIV Positive Selection Mutation Database | Positively selected mutations in HIV-1 protease and reverse transcriptase | http://bioinfo.mbi.ucla.edu/HIV | |
| 909 | Influenza Virus Resource | Protein and nucleotide sequences of the influenza virus | http://www.ncbi.nlm.nih.gov/genomes/FLU/FLU.html | |
| 993 | IVDB | Influenza Virus Database : Annotated sequences and geographic distribution of the influenza virus | http://influenza.genomics.org.cn | |
| 602 | NCBI Viral Genomes | Viral genome resource at NCBI | http://www.ncbi.nlm.nih.gov/genomes/VIRUSES/viruses.html | |
| 725 | Poxvirus.org | Poxvirus genomic sequences and gene annotation | http://www.poxvirus.org | |
| 750 | T4-like genome DB | Sequences of T4-like bacteriophages from various sources | http://phage.bioc.tulane.edu | |
| 201 | VIDA | Homologous viral protein families database | http://www.biochem.ucl.ac.uk/bsm/virus_database/VIDA.html | |
| 761 | VIPERdb | Virus particle explorer: Virus capsid structures | http://viperdb.scripps.edu/ | |
| 798 | Viral Bioinformatics Resource Center | Virus orthologous genes, gene families and genomes | http://www.biovirus.org | |
| 397 | VirGen | Curated database for complete viral genome sequences | http://bioinfo.ernet.in/virgen/virgen.html | |
| 1039 | ViTa | microRNAs targets of the influenza virus | http://vita.mbc.nctu.edu.tw | |
| 5.5. Prokaryotic genome databases | ||||
| 5.5.1. General | ||||
| 1044 | AlterORF | Database of alternate open reading frames | http://www.cienciavida.cl/alterorf/ | |
| 641 | BacMap | Picture atlas of annotated bacterial genomes | http://wishart.biology.ualberta.ca/BacMap | |
| 884 | Comparative Genometrics | DNA walks, nucleotide skews and other biometric measures of prokaryotic genomes | http://www.unil.ch/comparativegenometrics/ | |
| 70 | EMGlib | Enhanced microbial genomes library: Completely sequenced genomes of unicellular organisms | http://pbil.univ-lyon1.fr/emglib/emglib.html | |
| 328 | GeneDB | Curated database for various Sanger-sequenced genomes | http://www.genedb.org/ | |
| 611 | Genome Atlas | DNA structural properties of sequenced genomes | http://www.cbs.dtu.dk/services/GenomeAtlas/ | |
| 1084 | HEG-DB | Predicted highly expressed genes in prokaryotic genomes | http://genomes.urv.cat/HEG-DB | |
| 352 | HGT-DB | Horizontal Gene Transfer-DataBase | http://www.fut.es/~debb/HGT/ | |
| 828 | IMG | Comparative analysis of microbial genomes sequenced at the DOE Joint Genome Institute | http://img.jgi.doe.gov/ | |
| 1089 | IMG/M | A data management and analysis system for metagenomes | http://img.jgi.doe.gov/m | |
| 826 | Interrupted coding sequences DB | Interrupted coding sequences: frameshifts, stop codons, sequencing errors in microbial genomes | http://www-bio3d-igbmc.u-strasbg.fr/ICDS/ | |
| 837 | MeGX | Marine ecological genomix: genomics and metagenomics of marine bacteria | http://www.Megx.net | |
| 614 | MetaGrowth | Growth requirements of bacterial pathogens | http://igs-server.cnrs-mrs.fr/axenic/ | |
| 959 | MiST | Microbial Signal Transduction database | http://genomics.ornl.gov/mist/ | |
| 720 | PGTdb | Prokaryotic growth temperature database | http://pgtdb.csie.ncu.edu.tw/ | |
| 43 | RRNDB | rRNA operon numbers in various prokaryotes | http://rrndb.cme.msu.edu | |
| 1160 | Roundup | Repository of orthologs and corresponding evolutionary distances | http://rodeo.med.harvard.edu/tools/roundup | |
| 866 | SIDDBase | Stress-induced DNA duplex destabilization profiles of complete microbial genomes | http://www.genomecenter.ucdavis.edu/benham/siddbase/ | |
| 426 | xBase | A family of group-specific bacterial genome databases, includes coliBASE, CampyDB, ClostriDB, MycoDB, PseudoDB and others | http://xbase.bham.ac.uk/ | |
| 5.5.2. Escherichia coli | ||||
| 415 | ASAP | A Systematic Annotation Package | https://asap.ahabs.wisc.edu/annotation/php/ASAP1.htm | |
| 428 | CCDB | CyberCell Database | http://redpoll.pharmacy.ualberta.ca/CCDB | |
| 436 | coliBase | Database for E. coli, Salmonella and Shigella | http://colibase.bham.ac.uk/ | |
| 437 | Colibri | http://genolist.pasteur.fr/Colibri/ | ||
| 623 | EchoBASE | Post-genomic studies of Escherichia coli | http://www.ecoli-york.org/ | |
| 108 | EcoCyc | E. coli K12 genes, pathways, transporters, and gene regulation | http://ecocyc.org/ | |
| 69 | EcoGene | Sequence and literature data on E. coli genes and proteins | http://ecogene.org/ | |
| 1070 | ERIC | Enteropathogen Resource Integration Center | http://www.ericbrc.org | |
| 462 | Essential genes in E. coli | A list of genes essential for viability of E. coli | http://www.genome.wisc.edu/resources/essential.htm | |
| 482 | GenoBase | Functional genomic aAnalysis of E. coli in Japan | http://ecoli.aist-nara.ac.jp/ | |
| 165 | GenProtEC | E. coli K12 genome and proteome database | http://genprotec.mbl.edu | |
| 5.5.3. Bacillus subtilis | ||||
| 424 | BSORF | Bacillus subtilis Open Reading Frames | http://bacillus.genome.ad.jp/ | |
| 31 | DBTBS | Bacillus subtilis promoters and transcription factors | http://dbtbs.hgc.jp/ | |
| 89 | NRSub | Non-redundant Bacillus subtilis database at U. Lyon | http://pbil.univ-lyon1.fr/nrsub/nrsub.html | |
| 96 | SubtiList | Bacillus subtilis genome database at Institut Pasteur | http://genolist.pasteur.fr/SubtiList/ | |
| 5.5.4. Other bacteria | ||||
| 1153 | BuchneraBase | Genomic database for the pea aphid symbiont Buchnera sp. APS | http://www.buchnera.org/ | |
| 426 | CampyDB | Campylobacter Database | Incoroporated into xBase, no. 426 | |
| 648 | CIDB | Chlamydia Interactive Database: Gene expression data | http://www.it.deakin.edu.au/CIDB | |
| 433 | ClostriDB | Clostridium Database | Incoroporated into xBase, no. 426 | |
| 1167 | CoryneRegNet | Corynebacterial transcription factors | http://www.coryneregnet.de | |
| 68 | CyanoBase | Cyanobacterial genomes | http://www.kazusa.or.jp/cyano/ | |
| 834 | LEGER | Post-genome research of Listeria | http://leger2.gbf.de/cgi-bin/expLeger.pl | |
| 521 | LeptoList | Leptospira interrogans genome | http://www.bioinfo.hku.hk/LeptoList/. | |
| 534 | MolliGen | Genomic data on mollicutes | http://cbi.labri.fr/outils/molligen/ | |
| 896 | MtbRegList | Mycobacterium tuberculosis gene regulation | http://www.USherbrooke.ca/vers/MtbRegList | |
| 996 | MvirDB | Protein toxins, virulence factors, and antibiotic resistance genes | http://mvirdb.llnl.gov/ | |
| 944 | PAIDB | Pathogenicity islands in bacterial genomes | http://www.gem.re.kr/paidb | |
| 1000 | PATRIC | PathoSystems Resource Integration Center | https://patric.vbi.vt.edu | |
| 555 | PEC | Profiling of E. coli Chromosome | http://shigen.lab.nig.ac.jp/ecoli/pec | |
| 720 | PGTdb | Prokaryotic growth temperature database | http://pgtdb.csie.ncu.edu.tw/ | |
| 733 | PseudoCAP | Pseudomonas aeruginosa community genome annotation project | http://www.pseudomonas.com/ | |
| 947 | RegTransBase | Manually curated database of regulatory interactions in prokaryotes | http://regtransbase.lbl.gov | |
| 94 | RsGDB | Rhodobacter sphaeroides genome | http://www.hgsc.bcm.tmc.edu/projects/microbial/Rsphaeroides/ | |
| 865 | ShiBase | Shigella database | http://www.mgc.ac.cn/ShiBASE/ | |
| 760 | VFDB | Virulence Factors of pathogenic bacteria | http://www.mgc.ac.cn/cgi-bin/VFs/compatho.cgi | |
| 1017 | xanthusBase | Genome of the social bacterium Myxococcus xanthus | http://www.xanthusbase.org/ | |
| 5.5.5. Archaea | ||||
| 964 | Sulfolobus Database | Comparative genomics of Sulfolobus species | http://www.sulfolobus.org | |
| 876 | UCSC Archaeal Genome Browser | Pyrococcus furiosus genome browser | http://archaea.ucsc.edu/ | |
| 5.6. Unicellular eukaryotes genome databases | ||||
| 969 | ApiDB | Unified resource for various apicomplexan species | http://ApiDB.org | |
| 409 | ApiDots | EST sequences from various Apicomplexan parasites | http://www.cbil.upenn.edu/apidots/ | |
| 983 | Comparasite | Database for comparative study of parasite cDNAs | http://comparasite.hgc.jp/ | |
| 439 | CryptoDB | Cryptosporidium database | http://cryptodb.org/ | |
| 662 | Diatom EST DB | ESTs from diatom algae Thalassiosira and Phaeodactylum | http://www.biologie.ens.fr/diatomics/EST/ | |
| 446 | DictyBase | Universal resource for Dictyostelium discoideum | http://dictybase.org/ | |
| 72 | Full-Malaria | Full-length cDNA library from erythrocytic-stage Plasmodium | http://fullmal.ims.u-tokyo.ac.jp | |
| 917 | ParameciumDB | Paramecium genome sequencing project | http://paramecium.cgm.cnrs-gif.fr/db/index | |
| 91 | PlasmoDB | Plasmodium genome database | http://PlasmoDB.org | |
| 1124 | ProtozoaDB | Comparative analysis of protozoan genomes | http://protozoa.biowebdb.org/ | |
| 912 | TBestDB | Taxonomically broad EST database: protist ESTs | http://tbestdb.bcm.umontreal.ca/ | |
| 586 | TcruziDB | Trypanosoma cruzi genome database | http://tcruzidb.org/ | |
| 359 | ToxoDB | Toxoplasma gondii genome database | http://ToxoDB.org | |
| 910 | U-genome | Genome organization in unicellular eukaryotes | http://sege.ntu.edu.sg/wester/ugenome/ | |
| 5.7. Fungi | ||||
| 1056 | CFGP | Comparative Fungal Genomics Platform | http://cfgp.snu.ac.kr | |
| 955 | Fungal Genome Size Database | Genome sizes of various fungi | http://www.zbi.ee/fungal-genomesize/ | |
| 5.7.1. Yeasts | ||||
| 635 | AGD | Ashbya gossypii genome database | http://agd.unibas.ch | |
| 617 | CandidaDB | Candida albicans genome database | http://genolist.pasteur.fr/CandidaDB | |
| 645 | Candida Genome | Candida albicans genome database | http://www.candidagenome.org/ | |
| 441 | CYGD | MIPS Comprehensive yeast genome database | http://mips.gsf.de/proj/yeast | |
| 483 | Génolevures | A comparison of S. cerevisiae and 14 other yeast species | http://cbi.labri.fr/Genolevures | |
| 841 | Mpact | Yeast protein-protein interaction data | http://mips.gsf.de/genre/proj/mpact | |
| 730 | PROPHECY | Profiling of phenotypic characteristics in yeast | http://prophecy.lundberg.gu.se/ | |
| 576 | SCMD | Saccharomyces cerevisiae morphological database: micrographs of budding yeast mutants | http://yeast.gi.k.u-tokyo.ac.jp/ | |
| 577 | SCPD | Saccharomyces cerevisiae promoter database | http://rulai.cshl.edu/SCPD/ | |
| 357 | SGD | Saccharomyces genome database | http://www.yeastgenome.org/ | |
| 25 | TRIPLES | Transposon-insertion phenotypes, localization, and expression in Saccharomyces | http://ygac.med.yale.edu/triples/ | |
| 306 | YDPM | Yeast deletion project and mitochondria database | http://www-deletion.stanford.edu/YDPM/YDPM_index.html | |
| 342 | Yeast Intron Database | Ares lab database of splicesomal introns in S. cerevisiae | http://www.cse.ucsc.edu/research/compbio/yeast_ introns.html | |
| 792 | YEASTRACT | Yeast search for transcriptional regulators and consensus tracking | http://www.yeastract.com | |
| 254 | Yeast snoRNA DB | Yeast small nucleolar RNAs | http://www.bio.umass.edu/biochem/rna-sequence/ Yeast_snoRNA_Database/snoRNA_DataBase.html | |
| 791 | YGOB | Yeast gene order browser | http://wolfe.gen.tcd.ie/ygob | |
| 307 | yMGV | Yeast microarray global viewer | http://www.transcriptome.ens.fr/ymgv/ | |
| 531 | YMPD | Yeast mitochondrial protein database | http://bmerc-www.bu.edu/projects/mito/ | |
| 763 | YRC PDR | Yeast resource center public data repository | http://www.yeastrc.org/pdr/ | |
| 5.7.2. Other fungi | ||||
| 425 | CADRE | Central Aspergillus data repository | http://www.cadre.man.ac.uk/ | |
| 435 | COGEME | Phytopathogenic fungi and oomycete EST database | http://cogeme.ex.ac.uk | |
| 815 | FGDB | MIPS Fusarium graminearum genome database | http://mips.gsf.de/genre/proj/fusarium/ | |
| 525 | Magnaporthe grisea DB | Magnaporthe grisea Database | http://www.broad.mit.edu/annotation/genome/magnaporthe_grisea/Home.html | |
| 533 | MNCDB | MIPS Neurospora crassa database | http://mips.gsf.de/proj/neurospora/ | |
| 708 | OGD | Oomycete Genomics Database: ESTs and annotation | http://www.oomycete.net/ | |
| 852 | PHI-base | Genes affecting fungal pathogen-host interactions | http://www4.rothamsted.bbsrc.ac.uk/phibase/ | |
| 98 | Phytophthora Functional Genomics DB | ESTs and expression data from P. infestans and P. sojae | http://www.pfgd.org/pfgd/ | |
| 5.8. Invertebrates | ||||
| 5.8.1. Caenorhabditis elegans | ||||
| 430 | C. elegans Project | Genome sequencing data at the Sanger Institute | http://www.sanger.ac.uk/Projects/C_elegans | |
| 238 | Intronerator | Introns and splicing in C. elegans and C. briggsae | http://www.cse.ucsc.edu/~kent/intronerator/ | |
| 570 | RNAiDB | RNAi phenotypic analysis of C. elegans genes | http://www.rnai.org/ | |
| 864 | SGCEdb | Structural genomics of C. elegans | No longer maintained | |
| 304 | WorfDB | C. elegans ORFeome | http://worfdb.dfci.harvard.edu/ | |
| 51 | WormBase | Data repository for C. elegans and C. briggsae: curated genome annotation, genetic and physical maps, pathways | http://www.wormbase.org/ | |
| 961 | WormBook | Peer-reviewed chapters on the biology of C. elegans | http://www.wormbook.org | |
| 5.8.2. Drosophila melanogaster | ||||
| 774 | DPDB | Drosophila polymorphism database | http://dpdb.uab.es/ | |
| 928 | DroID | Drosophila gene and protein interaction data | http://www.droidb.org/ | |
| 449 | Drosophila microarray centre | Canadian Drosophila microarray centre | http://www.flyarrays.com/ | |
| 924 | DroSpeGe | Drosophila Species Genomes | http://insects.eugenes.org/DroSpeGe/ | |
| 816 | FLIGHT | Drosophila phenotypes, gene expression and protein interactions | http://flight.licr.org/ | |
| 71 | FlyBase | Drosophila sequences and genomic information | http://flybase.org/ | |
| 767 | FlyBrain | Database of the Drosophila nervous system | http://flybrain.neurobio.arizona.edu/ | |
| 670 | FlyMine | Integration of insect genomic and proteomic data | http://www.flymine.org | |
| 817 | FlyRNAi DRSC | Genome-wide RNAi analysis data in Drosophila | http://flyRNAi.org/cgi-bin/RNAi_screens.pl | |
| 1073 | FLYSNP | Single nucleotide polymorphism data for Drosophila melanogaster | http://flysnp.imp.univie.ac.at | |
| 1158 | FlyTF | Drosophila Transcription Factors | http://www.mrc-lmb.cam.ac.uk/genomes/FlyTF/ | |
| 467 | FlyTrap | Drosophila mutants created using protein trap strategy | http://flytrap.med.yale.edu/ | |
| 14 | FlyView | Drosophila development and genetics | http://flyview.uni-muenster.de/ | |
| 471 | GadFly | Genome annotation database of Drosophila | http://www.fruitfly.org | |
| 677 | GeniSys | Enhancer- and promoter-inserted mutants of Drosophila | http://genisys.kaist.ac.kr:8080 | |
| 989 | GenomeRNAi | Cell-based RNAi phenotypes database | http://www.dkfz.de/signaling/ernai/ernai.html | |
| 8 | Homophila | Drosophila homologs of human disease genes | http://superfly.ucsd.edu/homophila/ | |
| 509 | InterActive Fly | Drosophila genes and their roles in development | http://www.sdbonline.org/fly/aimain/1aahome.htm | |
| 1128 | REDfly | Regulatory modules and transcription factor binding sites in Drosophila | http://redfly.ccr.buffalo.edu | |
| 5.8.3. Other invertebrates | ||||
| 63 | ACeDB | C. elegans, S. pombe, and human genomic information | http://www.acedb.org/ | |
| 1152 | AphidBase | Genomic database for the pea aphid (Acyrthosiphon pisum) | http://www.aphidbase.com/ | |
| 410 | AppaDB | Database on the nematode Pristionchus pacificus | http://appadb.eb.tuebingen.mpg.de | |
| 643 | BeetleBase | Genome database of the beetle Tribolium castaneum | http://www.bioinformatics.ksu.edu/BeetleBase/ | |
| 1052 | ButterflyBase | Genomics of butterflies (Lepidoptera) | http://www.butterflybase.org | |
| 649 | Ciliate IES-MDS Db | Macro- and micronuclear genes in spirotrichous ciliates | http://oxytricha.princeton.edu/dimorphism/database.htm | |
| 434 | CnidBase | Cnidarian evolution and gene expression database | http://cnidbase.bu.edu/ | |
| 653 | CuticleDB | Structural proteins of Arthropod cuticle | http://bioinformatics.biol.uoa.gr/cuticleDB. | |
| 698 | LumbriBASE | ESTs of the earthworm Lumbricus rubellus | http://www.earthworms.org | |
| 543 | Nematode.net | Parasitic nematode sequencing project | http://nematode.net/ | |
| 544 | NEMBASE | Nematode sequence and functional data database | http://www.nematodes.org | |
| 726 | PPNEMA | Plant-parasitic nematode rRNAs | http://www.ppnema.uniba.it/ | |
| 1006 | Pristionchus.org | Genome data of the nematode Pristionchus pacificus | http://www.pristionchus.org | |
| 1161 | Sebida | Sex bias in insect gene expression database | http://www.sebida.de | |
| 743 | SilkDB | Silkworm Bombyx mori ESTs, mutants, photographs | http://www.ab.a.u-tokyo.ac.jp/genome/ | |
| 744 | SilkSatDb | A microsatellite database of the silkworm Bombyx mori | http://210.212.212.7:9999/PHP/SILKSAT/index.php | |
| 1133 | SmedGD | The Schmidtea mediterranea genome database | http://smedgd.neuro.utah.edu | |
| 747 | SpodoBase | Genomics of the butterfly Spodoptera frugiperda | http://bioweb.ensam.inra.fr/spodobase/ | |
| 871 | StellaBase | Nematostella vectensis (sea anemone) genome | http://stellabase.org. | |
| 873 | Tetrahymena Genome DB | Tetrahymena thermophila genome database | http://www.ciliate.org | |
| 1031 | VectorBase | Invertebrate Vectors of Human Pathogens | http://www.vectorbase.org | |
| 925 | wFleaBase | Daphnia Water Flea Genome Database | http://wfleabase.org/ | |
| 6. Metabolic Enzymes and Pathways; Signaling Pathways | ||||
| 898 | Pathguide | A listing of pathway, signal transduction and protein-protein interaction databases | http://pathguide.org | |
| 6.1. Enzymes and enzyme nomenclature | ||||
| 421 | BRENDA | Enzyme names and biochemical properties | http://www.brenda-enzymes.info/ | |
| 109 | ENZYME | Enzyme nomenclature and properties | http://www.expasy.org/enzyme/ | |
| 459 | Enzyme Nomenclature | IUBMB Nomenclature Committee recommendations | http://www.chem.qmul.ac.uk/iubmb/enzyme/ | |
| 613 | EzCatDB | Enzyme Catalytic Mechanism Database | http://mbs.cbrc.jp/EzCatDB/ | |
| 716 | FCP | Functional coverage of the proteome by structures | http://cgl.imim.es/fcp/ | |
| 508 | IntEnz | Integrated enzyme database and enzyme nomenclature | http://www.ebi.ac.uk/intenz | |
| 893 | MACiE | Mechanism, annotation and classification in enzymes: enzyme reaction mechanisms | http://www.ebi.ac.uk/thornton-srv/databases/MACiE/ | |
| 998 | ORENZA | ORphan ENZymes database | http://www.orenza.u-psud.fr/ | |
| 727 | PRECISE | Predicted and Consensus Interaction Sites in Enzymes | http://precise.bu.edu/precisedb/ | |
| 1121 | PROCOGNATE | Protein cognate ligands for the domains in enzyme structures | http://www.ebi.ac.uk/thornton-srv/databases/procognate/index.html | |
| 758 | SCOPEC | Mapping of catalytic function to domain structure | http://www.sbinf.org/~richard/enzome/ | |
| 772 | TECRdb | Thermodynamics of enzyme-catalyzed reactions | http://xpdb.nist.gov/enzyme_thermodynamics | |
| 6.2. Metabolic pathways | ||||
| 419 | BioCarta | Online maps of metabolic and signaling pathways | http://www.biocarta.com/genes/allPathways.asp | |
| 420 | BioCyc | Pathway/genome databases for many bacteria | http://biocyc.org/ | |
| 423 | Biodegradative Strain Database | Microorganisms that can degrade aromatic and other organic compounds | http://bsd.cme.msu.edu/ | |
| 644 | BioSilico | Integrated access to various metabolic databases | http://biosilico.kaist.ac.kr | |
| 991 | HMDB | The Human Metabolome Database: Curated human metabolite and metabolism data | http://www.hmdb.ca | |
| 112 | KEGG Pathway | Metabolic and regulatory pathways in complete genomes | http://www.genome.jp/kegg/pathway.html | |
| 835 | Lipid MAPS | Lipid metabolites and pathways strategy | http://www.lipidmaps.org | |
| 114 | MetaCyc | Metabolic pathways and enzymes from various organisms | http://metacyc.org | |
| 115 | PathDB | Biochemical pathways, compounds and metabolism | No longer maintained | |
| 612 | Reactome | Database of metabolic and signaling pathways | http://www.reactome.org/ | |
| 953 | SYSTOMONAS | SYSTems biology of pseudOMONAS | http://www.systomonas.de/ | |
| 117 | UM-BBD | University of Minnesota biocatalysis and biodegradation database | http://umbbd.msi.umn.edu/ | |
| 6.3. Protein-protein Interactions | ||||
| 633 | 3DID | 3D interacting domains: Domain-domain interactions in proteins with known 3D structures | http://3did.embl.de/ | |
| 1042 | 3D-Interologs | Protein-protein interactions in various evolutionary lineages | http://gemdock.life.nctu.edu.tw/3D-Interologs | |
| 796 | AffinDB | Affinity data for protein-ligand complexes | http://www.agklebe.de/affinity | |
| 405 | aMAZE | A system for the annotation, management, and analysis of biochemical and signalling pathway networks | http://www.scmbb.ulb.ac.be/amaze/ | |
| 1046 | AtPID | Arabidopsis thaliana Protein Interactome Database | http://atpid.biosino.org/ | |
| 1048 | Bacteriome.org | Protein interaction database for E. coli | http://www.bacteriome.org | |
| 103 | BIND | Biomolecular interaction network database | No longer free for all | |
| 1049 | Binding MOAD | Binding Mother of All Databases: protein-ligand crystal structures | http://www.BindingMOAD.org | |
| 800 | BioGRID | Genetic and physical interactions in yeast, worm and fly | http://www.thebiogrid.org | |
| 422 | BRITE | Biomolecular Relations in Information Transmission and Expression | http://www.genome.ad.jp/brite | |
| 980 | CellCircuits | Molecular network models: from pairwise molecular interactions to whole pathways | http://www.cellcircuits.org | |
| 1060 | CORUM | Experimentally verified mammalian protein complexes | http://mips.gsf.de/genre/proj/corum | |
| 946 | CutDB | Community annotation resource for proteases, their substrates and cleavage sites | http://cutdb.burnham.org/ | |
| 659 | DDIB | Database of domain interactions and binding | http://www.ddib.org/ | |
| 1066 | DIMA | Domain interaction map: experimental data and predictions on protein domain interactions | http://mips.gsf.de/genre/proj/dima2 | |
| 104 | DIP | Database of interacting proteins: Experimentally-determined protein-protein interactions | http://dip.doe-mbi.ucla.edu | |
| 1155 | Dockground | Protein-protein interfaces in co-crystallized protein structures | http://dockground.bioinformatics.ku.edu/ | |
| 1067 | DOMINE | Known and predicted protein domain interactions in PDB entries | http://domine.utdallas.edu | |
| 1033 | DOMINO | Domain peptide interactions | http://mint.bio.uniroma2.it/domino/ | |
| 105 | DRC | Database of ribosomal crosslinks | http://www.mpimg-berlin-dahlem.mpg.de/~ag_ribo/ag_brimacombe/drc/ | |
| 1086 | HotSprint | Hot spots (functionally and structurally important residues) in protein interfaces | http://prism.ccbb.ku.edu.tr/hotsprint/ | |
| 664 | hp-DPI | Database of protein interactions in Helicobacter pylori | http://dpi.nhri.org.tw/hp/ | |
| 688 | HPID | Human protein interaction database | http://www.hpid.org | |
| 897 | I2D | Interologous Interaction Database: Predicted protein-protein interactions in humans | http://ophid.utoronto.ca/i2d | |
| 507 | IntAct | Protein-protein interaction data | http://www.ebi.ac.uk/intact/ | |
| 770 | Inter-Chain Beta-Sheets | Protein interactions mediated by interchain beta-sheet formation | http://www.igb.uci.edu/servers/icbs/ | |
| 510 | InterDom | Putative protein domain interactions | http://interdom.i2r.a-star.edu.sg/ | |
| 138 | KDBI | Kinetic data of bio-molecular interactions | http://bioinf.xmu.edu.cn/databases/kdbi/kdbi.php | |
| 1091 | LigAsite | Biologically relevant binding sites in proteins with known structures | http://www.scmbb.ulb.ac.be/Users/benoit/LigASite | |
| 942 | MiMI | Michigan Molecular Interactions: Protein-protein interactions | http://mimi.ncibi.org/MiMI/home.jsp | |
| 1032 | MINT | Molecular INTeraction | http://mint.bio.uniroma2.it/mint/ | |
| 897 | OPHID | Online predicted human interaction database | Superseded by I2D (no. 897) | |
| 718 | PDZBase | Protein-protein interactions involving PDZ domains | http://icb.med.cornell.edu/services/pdz/start | |
| 1111 | PepCyber:P~Pep | Human protein interactions mediated by phosphoprotein-binding domains | http://PepCyber.umn.edu/PepCyber | |
| 773 | PINdb | Proteins interacting in nucleus (human and yeast) | http://pin.mskcc.org | |
| 748 | POINT | Prediction of human protein-protein interactome | http://point.bioinformatics.tw | |
| 729 | ProNIT | Protein-nucleic acid interactions | http://gibk26.bse.kyutech.ac.jp/jouhou/pronit/pronit.html | |
| 943 | PROTCOM | 3D structures of two-chain protein complexes | http://www.ces.clemson.edu/compbio/protcom | |
| 616 | PSIbase | Interaction of proteins with known 3D structures | http://psimap.org/index.php/PSIMAP | |
| 1012 | SNAPPI | Structures, iNterfaces and Alignments for Protein-Protein Interactions | http://www.compbio.dundee.ac.uk/SNAPPI/downloads.jsp | |
| 1134 | STITCH | Search Tool for Interactions of Chemicals | http://stitch.embl.de | |
| 749 | Structurally conserved interfaces | Interacting residues in protein-protein interfaces in PDB | http://home.ku.edu.tr/~okeskin/INTERFACE/INTERFACES.html | |
| 1138 | The Cell Cycle DB | Genes and proteins involved in human and yeast cell cycle | http://www.itb.cnr.it/cellcycle | |
| 960 | UniHI | Unified Human Interactome: human protein-protein interactions | http://www.mdc-berlin.de/unihi | |
| 6.4. Signaling pathways | ||||
| 419 | BioCarta | Online maps of metabolic and signaling pathways | http://www.biocarta.com/genes/allPathways.asp | |
| 794 | Cyclonet | Database on cell cycle regulation | http://cyclonet.biouml.org/index.html | |
| 890 | EndoNet | Information on endocrine networks | http://endonet.bioinf.med.uni-goettingen.de/ | |
| 1038 | Hedgehog signalling | Resources and annotations of the Hedgehog signaling pathway | http://hedgehog.sfsu.edu/ | |
| 1104 | NetworKIN | Network approach to human protein kinases and their substrates | http://networkin.info/ | |
| 1112 | PhosPhAt | Arabidopsis Protein Phosphorylation Site Database | http://www.plantenergy.uwa.edu.au/applications/phosphat/index.html | |
| 1175 | PRRDB | Pattern recognition receptors and their ligands | http://www.imtech.res.in/raghava/prrdb/ | |
| 858 | pSTIING | Protein signalling, transcriptional interactions and inflammation networks gateway | http://pstiing.licr.org/ | |
| 571 | ROSPath | Reactive oxygen species (ROS) signaling pathway | http://rospath.ewha.ac.kr | |
| 395 | STCDB | Signal Transduction Classification Database | http://bibiserv.techfak.uni-bielefeld.de/stcdb/ | |
| 1142 | UCSD-Nature Signaling Gateway | Expert-authored and peer-reviewed information on mammalian proteins involved in cellular signaling | http://www.signaling-gateway.org/molecule/ | |
| 7. Human and other Vertebrate Genomes | ||||
| 7.1. Model organisms, comparative genomics | ||||
| 879 | ABA | Ascidian body atlas: digital 3D model of ascidian development | http://ciona.lab.nig.ac.jp/ascidian/top.html | |
| 974 | AgBase | GO annotations for agriculturally important plants and animals | http://www.agbase.msstate.edu/ | |
| 26 | AllGenes | Human and mouse gene, transcript and protein annotation | http://www.allgenes.org | |
| 957 | Animal Genome Size Database | Genome sizes of vertebrates and invertebrates | http://www.genomesize.com | |
| 975 | AnimalQTLdb | Quantitative trait loci in livestock animals | http://www.animalgenome.org/QTLdb/ | |
| 65 | ArkDB | Genome databases for farm and other animals | http://www.thearkdb.org/ | |
| 12 | BodyMap | Human and mouse gene expression data | http://bodymap.ims.u-tokyo.ac.jp/ | |
| 881 | BodyMap-Xs | Cross-species comparison of vertebrate gene expression | http://bodymap.jp/ | |
| 647 | ChickVD | Sequence variation in the chicken genome | http://chicken.genomics.org.cn | |
| 286 | Cre Transgenic DB | Cre transgenic mouse lines with links to publications | http://www.mshri.on.ca/nagy/ | |
| 337 | CORG | COmparative Regulatory Genomics: conserved non-coding blocks | http://corg.molgen.mpg.de | |
| 808 | DBTGR | Database of tunicate Ciona gene regulation | http://dbtgr.hgc.jp/ | |
| 660 | DED | Database of evolutionary distances | No longer maintained | |
| 20 | Edinburgh Mouse Atlas | Digital atlas of mouse embryonic development | http://genex.hgu.mrc.ac.uk | |
| 453 | EGO | Eukaryotic Gene Orthologs | http://compbio.dfci.harvard.edu/tgi/ego/ | |
| 27 | Ensembl | Annotated information on eukaryotic genomes | http://www.ensembl.org/ | |
| 396 | euGenes | Genomic Information for Eukaryotic Organisms | http://eugenes.org/ | |
| 1071 | EuroPhenome | Large-scale phenotyping of knockout mouse lines | http://www.europhenome.eu | |
| 673 | GALA | Genomic alignment, annotation and experimental results | http://gala.cse.psu.edu/ | |
| 1076 | Gallus Gbrowse | Genomic information on chicken and other avian species | http://birdbase.net/ | |
| 1173 | GEISHA | Gallus expression in situ hybridization analysis | http://geisha.arizona.edu | |
| 15 | GXD | Mouse Gene Expression Database | http://www.informatics.jax.org/menus/expression_menu.shtml | |
| 605 | HomoloGene | Automatically detected homologous genes in complete eukaryotic genomes | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=homologene | |
| 8 | Homophila | Drosophila homologs of human disease genes | http://superfly.ucsd.edu/homophila/ | |
| 400 | KOG | Eukaryotic Orthologous Groups of proteins | http://www.ncbi.nlm.nih.gov/COG/ | |
| 952 | MamPol | Mammalia Polymorphism Database | http://mampol.uab.es | |
| 839 | MFunGD | MIPS mouse functional genomics database | http://mips.gsf.de/genre/proj/mfungd | |
| 87 | Mouse Genome DB | Formerly mouse genome database | http://www.informatics.jax.org | |
| 995 | Mouse Phenome DB | phenotypic and genotypic data from inbred strains of mice | http://www.jax.org/phenome | |
| 537 | Mouse SAGE | SAGE libraries from various mouse tissues and cell lines | http://mouse.biomed.cas.cz/sage | |
| 540 | Mouse Transposon Insertion Database | Mouse Transposon Insertion Database | http://mouse.ccgb.umn.edu/transposon/ | |
| 152 | Mouse Tumor Biology | Tumor types, genes, classification, incidence, pathology | http://tumor.informatics.jax.org | |
| 598 | Non-Human Genome Segmental Duplication DB | Segmental duplications in mouse, dog and chicken genomes | http://projects.tcag.ca/xenodup | |
| 548 | OMIA | Online Mendelian Inheritance in Animals | http://omia.angis.org.au/ | |
| 553 | ParaDB | Paralogy mapping in human genomes | http://abi.marseille.inserm.fr/paradb/ | |
| 554 | PathBase | European mutant mice histopathology database: images | http://www.pathbase.net/ | |
| 1110 | PBmice | piggyBac transposon insertions in the mouse genome. | http://www.scbit.org/PBmice/ | |
| 556 | PEDE | Pig Expression Data Explorer: Pig cDNA libraries and ESTs | http://pede.dna.affrc.go.jp | |
| 936 | PigGIS | Pig genome mapping, genes and ESTs | http://pig.genomics.org.cn/ | |
| 93 | Rat Genome Database | Rat genetic and genomic data | http://rgd.mcw.edu | |
| 625 | RatMap | Rat genome tools and data | http://ratmap.org | |
| 574 | RTCGD | Retroviral Tagged Cancer Gene Database | http://rtcgd.ncifcrf.gov/ | |
| 1164 | SPEED | Searchable prototype experimental evolutionary database | http://bioinfobase.umkc.edu/speed/speed_main.htm | |
| 751 | TAED | The Adaptive Evolution Database: plant and chordate gene families | http://www.bioinfo.no/tools/TAED | |
| 875 | TreeFam | Tree families database: phylogenetic trees of animal genes | http://www.treefam.org | |
| 1144 | UniTrap | Unambiguous insertions in the same subgenic regions of annotated mouse genes | http://unitrap.cbm.fvg.it/ | |
| 1145 | UTGB/medaka | University of Tokyo Genome Browser of medaka fish (Oryzias latipes) genomic data | http://medaka.utgenome.org/ | |
| 784 | VEGA | Vertebrate genome annotation: a repository for manual annotation of finished vertebrate genome sequences | http://vega.sanger.ac.uk/ | |
| 1150 | XenBase | Xenopus genomics resource | http://www.xenbase.org | |
| 101 | ZFIN | Zebrafish information network | http://zfin.org/ | |
| 7.2. Human genome databases, maps and viewers | ||||
| 985 | ENCODE Project | Encyclopedia of DNA Elements, all functional elements in the human genome | http://genome.ucsc.edu/ENCODE | |
| 56 | GDB | Human genes and genomic maps | http://www.gdb.org | |
| 35 | Gene Resource Locator | Alignment of ESTs with finished human sequence | No longer maintained | |
| 326 | GeneAnnot | Revised annotation of Affymetrix human gene probe sets | http://genecards.weizmann.ac.il/geneannot/ | |
| 350 | GeneCards | Integrated database of human genes, maps, proteins and diseases | http://bioinfo.weizmann.ac.il/genecards/ | |
| 348 | GeneLoc | Gene location database | http://genecards.weizmann.ac.il/geneloc/ | |
| 59 | GenMapDB | Mapped human BAC clones | http://genomics.med.upenn.edu/genmapdb | |
| 324 | HOWDY | Human organized whole genome database | http://www-alis.tokyo.jst.go.jp/HOWDY/ | |
| 77 | Human BAC Ends DB | Non-redundant human BAC end sequences | http://www.tigr.org/tdb/humgen/bac_end_search/bac_end_intro.html | |
| 597 | Human Genome Seg-mental Duplication DB | Segmental duplications in the human genome | http://projects.tcag.ca/humandup | |
| 61 | IXDB | Physical maps of human chromosome X | http://ixdb.mpimg-berlin-dahlem.mpg.de | |
| 54 | Map Viewer | Display of genomic information by chromosomal position | http://www.ncbi.nlm.nih.gov/mapview/ | |
| 859 | QTL Matchmaker | Quantitative trait loci mapping in human, mouse and rat | http://pmrc.med.mssm.edu:9090/QTL/jsp/qtlhome.jsp | |
| 62 | RHdb | Radiation hybrid map data | http://www.ebi.ac.uk/RHdb | |
| 592 | SKY/M-FISH and CGH | Fluorescent images of chromosomes and cytogenetic data | http://www.ncbi.nlm.nih.gov/sky/ | |
| 596 | The Chromosome 7 Annotation Project | Human chromosome 7 sequence and annotation | http://www.chr7.org | |
| 684 | TRBase | Tandem repeats in the human genome | http://trbase.ex.ac.uk/ | |
| 316 | UCSC Genome Browser | Genome assemblies and annotation | http://genome.ucsc.edu/ | |
| 319 | UniSTS | Unified view of sequence tagged sites with mapping data | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=unists | |
| 1149 | X:MAP | Annotation and visualization of genome structure for Affymetrix exon array analysis | http://xmap.picr.man.ac.uk | |
| 7.3. Human proteins | ||||
| 911 | Consensus CDS | Collaborative effort to identify a core set of human proteins | http://www.ncbi.nlm.nih.gov/projects/CCDS/ | |
| 1072 | Evola | Human genes and their vertebrate orthologs | http://jbirc.jbic.or.jp/hinv/evola/ | |
| 465 | FANTOM | Functional annotation of mouse full-length cDNA clones | http://fantom2.gsc.riken.go.jp | |
| 37 | FLJ-DB | Annotated full-length human cDNAs (formerly HUNT database) | http://fldb.hgc.jp/cgi-bin/cDNA3/public/publication/index.cgi | |
| 1037 | GeneSpeed | Protein domains in the expressed human, mouse, fly and worm genes | http://genespeed.ccf.org | |
| 685 | H-InvDB | Full-length human cDNA clones | http://www.h-invitational.jp/ | |
| 687 | Hoppsigen | Human and mouse homologous processed pseudogenes | http://pbil.univ-lyon1.fr/databases/hoppsigen.html | |
| 500 | HPRD | Human protein reference database: domain architecture, post-translational modifications, and disease association | http://www.hprd.org | |
| 171 | HUGE | Human unidentified gene-encoded large (>50 kDa) protein and cDNA sequences | http://www.kazusa.or.jp/huge/ | |
| 696 | IPI | International Protein Index | http://www.ebi.ac.uk/IPI | |
| 522 | LIFEdb | Localization, interaction and functions of human proteins | http://www.dkfz.de/LIFEdb | |
| 600 | Mammalian Gene Collection | Full-length open reading frame clones for human, mouse, and rat genes | http://mgc.nci.nih.gov/ | |
| 545 | NetAffx | Public Affymetrix probesets and annotations | http://www.affymetrix.com/ | |
| 550 | ORFDB | Collection of ORFs that are sold by Invitrogen | http://orf.invitrogen.com/ | |
| 1028 | PlasmID | A repository for collection and distribution of plasmid clones | http://plasmid.hms.harvard.edu/ | |
| 4 | STACK | Sequence tag alignment and consensus knowledgebase | http://www.sanbi.ac.za/Dbases.html | |
| 220 | SYSTERS | Systematic re-searching and clustering of proteins | http://systers.molgen.mpg.de/ | |
| 312 | trome, trEST, trGEN | Databases of predicted human protein sequences | ftp://ftp.isrec.isb-sib.ch/pub/databases/ | |
| 6 | UniGene | Unified clusters of ESTs and full-length mRNA sequences | http://www.ncbi.nlm.nih.gov/UniGene/ | |
| 8. Human Genes and Diseases | ||||
| 8.1. General human genetics databases | ||||
| 661 | DG-CST | Disease gene conserved sequence tags | http://143.225.208.11/cst3/ | |
| 57 | GenAtlas | Human genes, markers and phenotypes | http://www.genatlas.org/ | |
| 479 | Genetics Home Reference | A general guide on human hereditary diseases | http://ghr.nlm.nih.gov/ | |
| 680 | HAGR | Human ageing genomic resources: Genes related to ageing in humans and model organisms | http://genomics.senescence.info/ | |
| 683 | HCAD | Human chromosome aberration database: Chromosomal breakpoints and affected genes | http://www.pdg.cnb.uam.es/UniPub/HCAD/ | |
| 133 | HGMD | Human gene mutation database | Requires user registration | |
| 1087 | Human PAML Browser | Positive selection in human genes detected through genome comparison | http://mendel.gene.cwru.edu/adamslab/pbrowser.py | |
| 1100 | MSY Breakpoint Mapper | Sequence-tagged sites in the human Y chromosome | http://breakpointmapper.wi.mit.edu | |
| 1102 | MutDB | Predicted biochemical effects of human genetic variation: maping of SNPs on protein sequence and structure | http://mutdb.org/ | |
| 143 | OMIM | Online Mendelian inheritance in man: A catalog of human genetic and genomic disorders | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM | |
| 1163 | SNP2NMD | Human SNPs causing nonsense-mediated mRNA decay | http://variome.kobic.re.kr/SNP2NMD/ | |
| 8.2. General polymorphism databases | ||||
| 119 | ALFRED | Allele frequencies and DNA polymorphisms | http://alfred.med.yale.edu | |
| 793 | CTGA | Database for genetic disorders in Arabs | http://www.cags.org.ae | |
| 654 | Cypriot national mutation database | Disease mutations in the Cypriot population | http://www.goldenhelix.org/cypriot/ | |
| 125 | Cytokine Gene Poly-morphism Database | Cytokine gene polymorphism literature database | http://www.nanea.dk/cytokinesnps/ | |
| 655 | Database of Genomic Variants | Human genomic variants: frequency, segmental duplications and genome assembly gaps | http://projects.tcag.ca/variation/ | |
| 595 | dbQSNP | Quantification of SNP allele frequencies database | http://qsnp.gen.kyushu-u.ac.jp/ | |
| 886 | dbRIP | Human retrotransposon insertion polymorphism | http://falcon.roswellpark.org:9090/ | |
| 127 | dbSNP | Database of single nucleotide polymorphisms | http://www.ncbi.nlm.nih.gov/SNP/ | |
| 966 | D-HaploDB | Definitive haplotype database | http://orca.gen.kyushu-u.ac.jp | |
| 669 | FESD | Functional Element SNPs Database: SNPs located within promoters, UTRs, etc., of human genes | http://sysbio.kribb.re.kr/FESD/ | |
| 1020 | FINDBase | Frequencies of INherited Disorders | http://www.findbase.org | |
| 1074 | F-SNP | Functional effects of various human SNPs | http://compbio.cs.queensu.ca/F-SNP/ | |
| 344 | HapMap Project | A haplotype map of the human genome with patterns of DNA sequence variation | http://snp.cshl.org | |
| 131 | HGVbase | Human genome variation database: Curated human polymorphisms | http://hgvbase.cgb.ki.se | |
| 496 | HGVS Databases | A compilation of human mutation databases | http://www.hgvs.org/ | |
| 517 | JSNP | Japanese SNP database | http://snp.ims.u-tokyo.ac.jp/ | |
| 665 | PhenomicDB | Comparison of phenotypes of orthologous genes in human and model organisms | http://www.phenomicdb.de | |
| 973 | PolyDoms | Human coding SNPs mapped onto protein domains | http://polydoms.cchmc.org | |
| 724 | Polymorphix | Database of sequence polymorphisms | http://pbil.univ-lyon1.fr/polymorphix/query.php | |
| 146 | Protein Mutant DB | Compilation of protein mutant data | http://pmd.ddbj.nig.ac.jp/ | |
| 1011 | SNAP | An integrated SNP Annotation Platform | http://platform.humgen.au.dk/ | |
| 1030 | SNP@Ethnos | Human SNPs and genes that contain human ethnic variation | http://bioportal.kobic.re.kr/SNPatETHNIC/ | |
| 626 | SNPeffect & PupaSuite | Phenotypic effects of human coding SNPs | http://snpeffect.vib.be/ | |
| 590 | TopoSNP | Topographic database of non-synonymous SNPs | http://gila.bioengr.uic.edu/snp/toposnp | |
| 755 | TPMD | Taiwan polymorphic microsatellite marker database | http://tpmd.nhri.org.tw | |
| 8.3. Cancer gene databases | ||||
| 122 | Atlas of Genetics and Cytogenetics in Onco-logy and Haematology | Cancer related genes, chromosomal abnormalities in oncology and haematology, and cancer-prone diseases | http://atlasgeneticsoncology.org/ | |
| 593 | Cancer Chromosomes | Cytogenetic, clinical, and reference information on cancer-related aberrations | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=cancerchromosomes | |
| 951 | CancerGenes | Gene selection resource for cancer genome projects | http://cbio.mskcc.org/cancergenes | |
| 1053 | CanGEM | Gene copy number changes in cancer | http://www.cangem.org/ | |
| 431 | CGED | Cancer Gene Expression Database | http://lifesciencedb.jp/cged/ | |
| 651 | COSMIC | Catalogue Of Somatic Mutations In Cancer: Sequence data, samples and publications | http://www.sanger.ac.uk/perl/CGP/cosmic | |
| 126 | Database of Germline p53 Mutations | Mutations in human tumor and cell line p53 gene | http://www.lf2.cuni.cz/projects/germline_mut_p53.htm | |
| 889 | EHCO | Encyclopedia of hepatocellular carcinoma genes online | http://ehco.iis.sinica.edu.tw | |
| 822 | HPTAA | Human potential tumor-associated antigens | http://www.bioinfo.org.cn/hptaa/ | |
| 134 | Human p53, human hprt, rodent lacI and rodent lacZ databases | Mutations at the human p53 and hprt genes; rodent transgenic lacI and lacZ mutations | http://www.ibiblio.org/dnam/mainpage.html | |
| 362 | IARC TP53 Database | Human TP53 somatic and germline mutations | http://www-p53.iarc.fr/index.html | |
| 833 | ITTACA | Integrated tumor transcriptome array and clinical data analysis | http://bioinfo.curie.fr/ittaca | |
| 1096 | MethyCancer | Links between DNA methylation levels and cancer | http://methycancer.genomics.org.cn | |
| 1026 | OncoDB.HCC | Oncogenomic database of hepatocellular carcinoma | http://oncodb.hcc.ibms.sinica.edu.tw | |
| 153 | Oral Cancer Gene DB | Cellular and molecular data for genes involved in oral cancer | Incorporated into TGDBs, no. 155 | |
| 1125 | PubMeth | Links between DNA methylation levels and cancer | http://matrix.ugent.be/pubmeth/ | |
| 579 | SNP500Cancer | Re-sequenced SNPs from 102 reference samples | http://snp500cancer.nci.nih.gov | |
| 149 | SV40 Large T-Antigen Mutant Database | Mutations in SV40 large tumor antigen gene | http://supernova.bio.pitt.edu/pipaslab/ | |
| 922 | Tumor-Associated Genes Database | Tumor-associated genes database | http://www.binfo.ncku.edu.tw/TAG/GeneDoc.php | |
| 155 | Tumor Gene Family Databases (TGDBs) | Cellular, molecular and biological data about genes involved in various cancers | http://www.tumor-gene.org/tgdf.html | |
| 768 | ALPSbase | Autoimmune lymphoproliferative syndrome database | http://research.nhgri.nih.gov/ALPS/ | |
| 8.4. Gene-, system- or disease-specific databases | ||||
| 788 | AlzGene | Candidate genes for Alzheimer disease | http://www.alzgene.org | |
| 120 | Androgen Receptor Gene Mutations DB | Mutations in the androgen receptor gene | http://www.mcgill.ca/androgendb/ | |
| 393 | AngioDB | Database of angiogenesis and angiogenesis-related molecules | http://angiodb.snu.ac.kr/ | |
| 416 | BayGenomics | Publicly available mouse gene trap cell lines | Superseded by Gene Trap database, no. 827 | |
| 417 | BGED | Brain Gene Expression Database | http://genome.mc.pref.osaka.jp/BGED/ | |
| 123 | BTKbase | Mutation registry for X-linked agammaglobulinemia | http://bioinf.uta.fi/BTKbase/ | |
| 594 | CarpeDB | Comprehensive database on the genetics of epilepsy | http://www.carpedb.ua.edu | |
| 124 | CASRDB | Calcium-sensing receptor database: CASR mutations causing hypercalcemia and/or hyperparathyroidism | http://www.casrdb.mcgill.ca/ | |
| 137 | Collagen Mutation DB | Human type I and type III collagen gene mutations | http://www.le.ac.uk/genetics/collagen/ | |
| 887 | DENIZ | Beta-thalassemia allele frequencies in world populations | No longer maintained | |
| 454 | EICO DB | Expression-based Imprint Candidate Organiser | http://fantom2.gsc.riken.jp/EICODB/ | |
| 110 | EpoDB | Genes expressed during human Erythropoiesis database | http://www.cbil.upenn.edu/EpoDB/ | |
| 460 | ERGDB | Estrogen Responsive Genes Database | http://sdmc.lit.org.sg/ergdb/cgi-bin/explore.pl | |
| 464 | EyeSite | Families of proteins functioning in the eye | http://eyesite.cryst.bbk.ac.uk/ | |
| 363 | GOLD.db | Genomics Of Lipid-associated Disorders | http://gold.tugraz.at | |
| 130 | HaemB | Factor IX gene mutations, insertions and deletions | http://www.kcl.ac.uk/ip/petergreen/haemBdatabase.html | |
| 491 | HbVar | Human hemoglobin variants and thalassemias | http://globin.cse.psu.edu/globin/hbvar | |
| 907 | HDBase | A website for Huntington's disease research | http://hdbase.org/ | |
| 493 | HemBase | Genes expressed in differentiating human erythroid cells | http://hembase.niddk.nih.gov/ | |
| 494 | HemoPDB | Hematopoietic Promoter Database | http://bioinformatics.med.ohio-state.edu/HemoPDB | |
| 366 | HORDE | Human Olfactory Receptor Data Exploratorium | http://bioinfo.weizmann.ac.il/HORDE/ | |
| 293 | HOX-PRO | Homeobox genes database | http://www.iephb.nw.ru/labs/lab38/spirov/hox_pro/hox-pro00.html | |
| 499 | HPMR | Human plasma membrane receptome: sequences, literature, and expression data | http://receptome.stanford.edu/ | |
| 135 | Human PAX2 Allelic Variant Database | Mutations in human PAX2 gene | http://pax2.hgu.mrc.ac.uk/ | |
| 136 | Human PAX6 Allelic Variant Database | Mutations in human PAX6 gene | http://pax6.hgu.mrc.ac.uk/ | |
| 501 | IL2Rgbase | X-linked severe combined immunodeficiency mutation database | http://research.nhgri.nih.gov/scid/ | |
| 294 | Imprinted Gene Catalogue | Imprinted genes and parent-of-origin effects in animals | http://igc.otago.ac.nz/home.html | |
| 506 | INFEVERS | Hereditary inflammatory disorder and familial mediterranean fever mutation data | http://fmf.igh.cnrs.fr/infevers | |
| 949 | KBERG | KnowledgeBase for Estrogen Responsive Genes | http://research.i2r.a-star.edu.sg/kberg | |
| 139 | KinMutBase | Disease-causing protein kinase mutations | http://www.uta.fi/imt/bioinfo/KinMutBase/ | |
| 523 | Lowe Syndrome Mutation Database | Mutations causing Lowe oculocerebrorenal syndrome | http://research.nhgri.nih.gov/lowe/ | |
| 142 | NCL Resource | Polymorphisms in neuronal ceroid lipofuscinoses genes | http://www.ucl.ac.uk/ncl/ | |
| 1025 | NEIbank | EyeSAGE, EyeBrowse and Eye Disease Gene databases | http://neibank.nei.nih.gov | |
| 144 | PAHdb | Mutations at the phenylalanine hydroxylase locus | http://www.pahdb.mcgill.ca | |
| 559 | PGDB | Prostate and prostatic diseases gene database | http://www.ucsf.edu/pgdb/ | |
| 145 | PHEXdb | PHEX mutations causing X-linked hypophosphatemia | http://www.phexdb.mcgill.ca | |
| 154 | Prostate Expression DB | Prostate expression database: ESTs from prostate tissue and cell type-specific cDNA libraries | http://www.pedb.org/ | |
| 147 | PTCH1 Mutation DB | Mutations and SNPs found in PTCH1 gene | http://www.cybergene.se/cgi-bin/w3-msql/ptchbase/index.html | |
| 148 | RB1 Gene Mutation DB | Mutations in the human retinoblastoma (RB1) gene | http://www.verandi.de/joomla/ | |
| 769 | SCAdb | Spinocerebellar ataxia candidate gene database | http://ymbc.ym.edu.tw/sca_ensembl/ | |
| 787 | SynDB | Synapse protein database | http://syndb.cbi.pku.edu.cn | |
| 632 | T1Dbase | A resource for type 1 diabetes research | http://t1dbase.org | |
| 752 | The Autism Chromoso-me Rearrangement DB | Curated collection of genomic features related to autism | http://projects.tcag.ca/autism | |
| 753 | The Lafora Database | The Lafora progressive myoclonus epilepsy mutation and polymorphism database | http://projects.tcag.ca/lafora/ | |
| 907 | T-REGs | A list of TGFbeta-responsive genes | No longer maintained | |
| 9. Microarray Data and other Gene Expression Databases | ||||
| 1043 | 4DXpress | Database for cross species expression pattern comparisons | http://ani.embl.de/4DXpress | |
| 634 | 5'SAGE | 5'-end serial analysis of gene expression | http://5sage.gi.k.u-tokyo.ac.jp/ | |
| 338 | ArrayExpress | Public collection of microarray gene expression data | http://www.ebi.ac.uk/arrayexpress | |
| 11 | Axeldb | Gene expression in Xenopus laevis | http://www.dkfz.de/en/mol_embryology/axeldb.html | |
| 802 | CAGE | CAGE tags for cap-analysis of gene expression | http://fantom31p.gsc.riken.jp/cage/mm5/ | |
| 427 | CATMA | Complete Arabidopsis Transcriptome MicroArray | http://www.catma.org | |
| 432 | CleanEx | Expression reference database, linking heterogeneous expression data to facilitate cross-dataset comparisons | http://www.cleanex.isb-sib.ch/ | |
| 1064 | CycleBase | Gene expression profiles from cell-cycle microarray studies | http://www.cyclebase.org | |
| 657 | dbERGEII | Database of experimental results on gene expression: Genomic alignment, annotation and experimental data | http://dberge.cse.psu.edu/menu.html | |
| 1170 | dbLEP | Database of Liver proteome expression profiles | http://lep.hupo.org.cn/main.htm | |
| 812 | EMAGE | Edinburgh mouse atlas gene expression database | http://genex.hgu.mrc.ac.uk/Emage/database | |
| 13 | EPConDB | Gene expression in pancreatic development, beta cell function and diabetes | http://www.cbil.upenn.edu/EPConDB | |
| 987 | Gene Aging Nexus | Aging-related gene expression data | http://gan.usc.edu | |
| 24 | Gene Expression in Tooth Database | Gene expression in dental tissue | http://bite-it.helsinki.fi/ | |
| 325 | GeneNote | Human genes expression profiles in healthy tissues | http://genecards.weizmann.ac.il/genenote/ | |
| 330 | GenePaint | Gene expression patterns in the mouse | http://www.genepaint.org/Frameset.html | |
| 676 | GeneTide | A transcriptome-focused member of the GeneCards suite | http://genecards.weizmann.ac.il/genetide/ | |
| 481 | GeneTrap | Expression patterns in an embryonic stem library of gene trap insertions | http://www.cmhd.ca/genetrap/ | |
| 918 | GENSAT | Gene Expression Nervous System Atlas: a map of gene expression in the central nervous system of the mouse | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gensat | |
| 603 | GEO | Gene Expression Omnibus: Public gene expression repository | http://www.ncbi.nlm.nih.gov/geo/ | |
| 485 | GermOnline | Gene expression in mitotic and meiotic cell cycle | http://www.germonline.org/ | |
| 891 | GPX-Macrophage | Gene expression in macrophages | http://ebola.gti.ed.ac.uk:8090/GPX/htdocs/index.html | |
| 23 | HuGEIndex | Human Gene Expression Index: Expression levels in normal tissues | http://zlab.bu.edu/HugeSearch | |
| 16 | Interferon Stimulated Gene Database | Genes induced by treatment with interferons | http://www.lerner.ccf.org/labs/williams/xchip-html.cgi | |
| 827 | International Gene Trap Consortium DB | Publicly available gene trap cell lines in mouse | http://www.genetrap.org/ | |
| 17 | Kidney Development Database | Kidney development and gene expression | http://golgi.ana.ed.ac.uk/kidhome.html | |
| 778 | LOLA | List of lists annotated: a comparison of gene sets identified in different microarray experiments | http://www.lola.gwu.edu/ | |
| 1092 | M3D | Many Microbe Microarrays Database | http://m3d.bu.edu/ | |
| 18 | MAGEST | Ascidian (Halocynthia roretzi) gene expression patterns | http://magest.hgc.jp/ | |
| 699 | MAMEP | Molecular Anatomy of the Mouse Embryo Project | http://mamep.molgen.mpg.de/ | |
| 339 | MEPD | Gene expression in medaka (freshwater fish Oryzias latipes) | http://www.embl.de/mepd/ | |
| 541 | NASCarrays | Nottingham Arabidopsis Stock Centre microarray database | http://affymetrix.arabidopsis.info | |
| 709 | OncoMine | Cancer microarray data by gene or cancer type | http://www.oncomine.org/ | |
| 558 | PEPR | Public Expression Profiling Resource | http://pepr.cnmcresearch.org | |
| 568 | RefExA | Reference database for human gene expression analysis | http://www.lsbm.org/site_e/database/index.html | |
| 739 | rOGED | Rat ovarian gene expression database | http://app.mc.uky.edu/kolab/rogedendo.aspx | |
| 712 | SAGEmap | NCBI's resource for SAGE data from various organisms | http://www.ncbi.nlm.nih.gov/SAGE | |
| 742 | SIEGE | Smoking Induced Epithelial Gene Expression | http://pulm.bumc.bu.edu/siegeDB | |
| 22 | Stanford Microarray DB | Raw and normalized data from microarray experiments | http://genome-www.stanford.edu/microarray | |
| 1139 | TMAD | The Stanford Tissue Microarray Database | http://tma.stanford.edu | |
| 905 | TmaDB | Tissue microarray database | http://www.bioinformatics.leeds.ac.uk/tmadb/ | |
| 10. Proteomics Resources | ||||
| 606 | 2D-PAGE | Proteome database system for microbial research | http://www.mpiib-berlin.mpg.de/2D-PAGE | |
| 1050 | Biodefense Proteomics Resource Center | Proteomics and host-pathogen interactions for biodefense-related microorganisms | http://www.proteomicsresource.org/default.aspx | |
| 731 | DynaProt 2D | Proteome database of Lactococcus lactis | http://www.wzw.tum.de/proteomik/lactis/ | |
| 222 | GELBANK | 2D gel electrophoresis patterns of proteins from complete microbial genomes | http://gelbank.anl.gov | |
| 950 | MAPU | Max-Planck Unified proteome database | http://www.mapuproteome.com | |
| 710 | Open Proteomics DB | Mass-spectrometry-based proteomics data for human, yeast, E. coli and Mycobacterium | http://bioinformatics.icmb.utexas.edu/OPD/ | |
| 850 | PepSeeker | Peptide identification and ion information from proteome experiments | http://nwsr.bms.umist.ac.uk/cgi-bin/pepseeker/pepseek.pl | |
| 851 | PeptideAtlas | Peptides identified in LC-MS/MS proteomics experiments | http://www.peptideatlas.org | |
| 721 | PlantMarkers | Database of predicted molecular markers from plants | http://markers.btk.fi | |
| 857 | PRIDE | Proteomics peptide identification database | http://www.ebi.ac.uk/pride/ | |
| 225 | SWISS-2DPAGE | Annotated 2D gel electrophoresis database | http://www.expasy.org/ch2d/ | |
| 11. Other Molecular Biology Databases | ||||
| 256 | BioImage | Database of multidimensional biological images | http://www.bioimage.org/ | |
| 801 | BioModels | Published mathematical models of biological interest | http://www.ebi.ac.uk/biomodels/ | |
| 1171 | Déjà vu | Duplicate citations in the scientific literature | http://spore.swmed.edu/dejavu/ | |
| 298 | PubMed | Citations and abstracts of biomedical literature | http://pubmed.gov | |
| 992 | University of Pittsburgh Bioinformatics Resources Collection | A collection of bioinformatic databases and software tools | http://www.hsls.pitt.edu/guides/genetics/obrc/ | |
| 701 | MetaRouter | Compounds and pathways related to bioremediation | http://pdg.cnb.uam.es/MetaRouter | |
| 11.1. Drugs and drug design | ||||
| 407 | ANTIMIC | Database of natural antimicrobial peptides | http://research.i2r.a-star.edu.sg/Templar/DB/ANTIMIC/ | |
| 408 | APD | Antimicrobial Peptide Database | http://aps.unmc.edu/AP/main.php | |
| 1055 | CEBS | Database of toxicogenomics, microarray and proteomics data. | http://cebs.niehs.nih.gov | |
| 443 | DART | Drug Adverse Reaction Targets | http://xin.cz3.nus.edu.sg/group/drt/dart.asp | |
| 811 | DrugBank | Combined information on drugs and drug targets | http://redpoll.pharmacy.ualberta.ca/drugbank/ | |
| 819 | GLIDA | G-protein coupled receptors ligand database | http://pharminfo.pharm.kyoto-u.ac.jp/services/glida/ | |
| 1002 | PharmGED | PharmacoGenetic Effect Database | http://bidd.cz3.nus.edu.sg/phg/ | |
| 392 | PharmGKB | Pharmacogenomics and Pharmacogenetics Knowledge Base | http://www.pharmgkb.org | |
| 741 | Scorpion | Database of scorpion toxins | http://sdmc.i2r.a-star.edu.sg/scorpion/ | |
| 902 | SuperDrug | 2D and 3D chemical structures of various drugs | http://bioinformatics.charite.de/superdrug | |
| 903 | SuperNatural | Natural compounds and their suppliers | http://bioinformatics.charite.de/supernatural | |
| 1136 | SuperTarget | Drug-related information: medical indications, adverse drug effects, drug metabolism and Gene Ontology terms of the target proteins | http://insilico.charite.de/supertarget | |
| 315 | TTD | Therapeutic target database | http://xin.cz3.nus.edu.sg/group/cjttd/ttd.asp | |
| 1147 | VIOLIN | Vaccine Investigation and Online Information Network | http://www.violinet.org | |
| 11.2. Molecular probes and primers | ||||
| 781 | AOBase | Antisense oligonucleotide selection and design | http://www.bioit.org.cn/ao/aobase | |
| 505 | IMGT/PRIMER-DB | Immunogenetics oligonucleotide primer database | http://imgt3d.igh.cnrs.fr/PrimerDB/Query_PrDB.pl | |
| 296 | MPDB | Molecular Probe Database | http://www.biotech.ist.unige.it/interlab/mpdb.html | |
| 728 | Primer Studio | PCR primers for eukaryotic and prokaryotic genes | http://bioinfo.ebc.ee/PrimerStudio/ | |
| 390 | probeBase | rRNA-targeted oligonucleotide probe sequences, DNA microarray layouts, and associated information | http://www.microbial-ecology.net/probebase | |
| 736 | QPPD | Quantitative PCR Primer Database | http://web.ncifcrf.gov/rtp/GEL/primerdb/default.asp | |
| 1008 | qPrimerDepot | Quantitative real time PCR primers for human RefSeq sequences | http://primerdepot.nci.nih.gov/ | |
| 356 | RTPrimerDB | Real-time PCR primer and probe sequences | http://medgen.ugent.be/rtprimerdb/ | |
| 303 | VirOligo | Virus-specific oligonucleotides for PCR and hybridization | http://viroligo.okstate.edu | |
| 12. Organelle Databases | ||||
| 804 | Chloroplast genome DB | Chloroplast genome database | http://chloroplast.cbio.psu.edu/ | |
| 74 | GOBASE | Organelle genome database | http://megasun.bch.umontreal.ca/gobase/gobase.html | |
| 713 | Organelle DB | Organelle proteins and subcellular structures | http://organelledb.lsi.umich.edu/ | |
| 601 | Organelle genomes | NCBI's organelle genome resource | http://www.ncbi.nlm.nih.gov/genomes/ORGANELLES/organelles.html | |
| 1001 | PeroxisomeDB | Peroxisomal proteins, metabolic routes and diagnostic tools | http://www.peroxisomeDB.org | |
| 1115 | Plant Organelles DB | Images and protocols for plant organelle research | http://podb.nibb.ac.jp/Organellome | |
| 722 | PLprot | Plastid protein database | http://www.plprot.ethz.ch/ | |
| 12.1. Mitochondrial Genes and Proteins | ||||
| 637 | AMPDB | Arabidopsis Mitochondrial Protein Database | http://www.plantenergy.uwa.edu.au/applications/ampdb/index.html | |
| 686 | HMPD | Human mitochondrial protein database | http://bioinfo.nist.gov/hmpd/ | |
| 1174 | HmtDB | Human mitochondrial database | http://www.hmtdb.uniba.it/ | |
| 824 | Human MtDB | Human mitochondrial genome database | http://www.genpat.uu.se/mtDB | |
| 38 | HvrBase++ | Primate mitochondrial DNA control region sequences | http://www.hvrbase.org | |
| 894 | MamMiBase | Mammalian mitochondrial genome database | http://xavante.fmrp.usp.br/mammibase/ | |
| 64 | Mitochondriome | Metazoan mitochondrial genes | http://www.ba.itb.cnr.it/mitochondriome/ | |
| 83 | MitoDat | Mitochondrial proteins (predominantly human) | http://www-lecb.ncifcrf.gov/mitoDat/ | |
| 84 | MITOMAP | Human mitochondrial genome | http://www.mitomap.org/ | |
| 1099 | Mitome | Comparative analysis of metazoan mitochondrial genomes | http://www.mitome.info | |
| 86 | MITOP2 | Mitochondrial proteins, genes and diseases | http://www.mitop2.de/ | |
| 532 | MitoProteome | Experimentally described human mitochondrial proteins | http://www.mitoproteome.org | |
| 538 | MPIMP db | Mitochondrial protein import machinery of plants and yeast | http://www.plantenergy.uwa.edu.au/applications/mpimp/ | |
| 547 | OGRe | Organellar Genome Resource | http://ogre.mcmaster.ca | |
| 13. Plant Databases | ||||
| 13.1. General plant databases | ||||
| 599 | BarleyBase | Expression profiling of plant genomes | http://www.barleybase.org/ | |
| 982 | Cereal Small RNA DB | Small RNAs expressed in rice and maize | http://sundarlab.ucdavis.edu/smrnas/ | |
| 624 | CR-EST | Cropp ESTs: Barley, wheat, pea, and potato ESTs | http://pgrc.ipk-gatersleben.de/cr-est/ | |
| 888 | DRASTIC | Database resource for analysis of signal transduction in plant cells | http://www.drastic.org.uk | |
| 128 | FLAGdb++ | Integrative database about plant genomes | http://urgv.evry.inra.fr/projects/FLAGdb++/HTML/index.shtml | |
| 672 | GabiPD | Central database of the German Plant Genome Project | http://gabi.rzpd.de | |
| 675 | GeneFarm | Expert annotation of Arabidopsis gene and protein families | http://urgi.versailles.inra.fr/Genefarm/ | |
| 351 | GénoPlante-Info | Plant genomic data from the Génoplante consortium | http://www.genoplante.com/ | |
| 488 | GrainGenes | Genes and phenotypes of wheat, barley, rye, triticale, oats | http://wheat.pw.usda.gov | |
| 607 | Gramene | A resource for comparative grass genomics | http://www.gramene.org | |
| 1095 | MetaCrop | Biochemical pathways and enzymes in crop plants | http://metacrop.ipk-gatersleben.de | |
| 1029 | MIPSPlantsDB | MIPS Plants Databases | http://mips.gsf.de/proj/plant/jsf/ | |
| 581 | openSputnik | Plant EST clustering and functional annotation | No longer maintained | |
| 999 | PathoPlant | Signal transduction related to plant-pathogen interactions | http://www.pathoplant.de | |
| 853 | Phytome | Comparative genomics of plant species | http://www.phytome.org | |
| 956 | Plant DNA C-values Database | Genome sizes of various plants and algae | http://www.kew.org/genomesize/homepage.html | |
| 562 | Plant Genome Central | NCBI’s portal for various large-scale plant genome and EST sequencing projects | http://www.ncbi.nlm.nih.gov/genomes/PLANTS/PlantList.html | |
| 843 | Plant MPSS | Massively parallel signature sequencing of plant genes | http://mpss.udel.edu | |
| 1116 | Plant Stress-Responsive Gene Catalog | Stress-responsive gene in various plant species | http://dayhoff.generationcp.org | |
| 355 | PlantGDB | Plant genome database: Actively-transcribed plant genes | http://www.plantgdb.org/ | |
| 1118 | PlantTribes | Families of protein-coding genes from five sequenced plant species | http://www.floralgenome.org/tribe.php | |
| 948 | POGs/PlantRBP | Orthologous groups of RNA binding proteins in plants | http://plantrbp.uoregon.edu | |
| 1119 | PPDB | Plant promoter database | http://ppdb.gene.nagoya-u.ac.jp | |
| 578 | SeedGenes | Genes essential for Arabidopsis development | http://www.seedgenes.org/ | |
| 940 | TIGR Plant Transcript Assembly database | Transcript assemblies of plant EST and cDNA sequences | http://plantta.tigr.org | |
| 313 | TropGENE DB | Genes and genomes of sugarcane, banana, cocoa | http://tropgenedb.cirad.fr/ | |
| 67 | UK CropNet | Genome mapping in crop plants | http://ukcrop.net/ | |
| 13.2. Arabidopsis thaliana | ||||
| 636 | AGNS | Arabidopsis GeneNet supplementary | http://wwwmgs.bionet.nsc.ru/agns/ | |
| 618 | AGRIS | Arabidopsis gene regulatory information server | http://arabidopsis.med.ohio-state.edu | |
| 780 | Arabidopsis MPSS | Arabidopsis gene expression detected by massively parallel signature sequencing | http://mpss.udel.edu/at/ | |
| 638 | Arabidopsis Nucleolar Protein Database | Comparative analysis of human and Arabidopsis nucleolar proteomes | http://bioinf.scri.sari.ac.uk/cgi-bin/atnopdb/proteome_comparison | |
| 640 | Arabidopsis Small RNA Project | Arabidopsis Small RNA sequences | http://asrp.cgrb.oregonstate.edu/ | |
| 880 | ARTADEdb | Arabidopsis tiling-array-based detection of exons | http://omicspace.riken.jp/ARTADE/ | |
| 394 | AtGDB | Arabidopsis thaliana genome database | http://www.plantgdb.org/AtGDB | |
| 765 | AthaMap | Genome-wide map of putative transcription factor binding sites in Arabidopsis thaliana | http://www.athamap.de/ | |
| 934 | ATTED-II | Coexpressed gene sets and gene regulators in Arabidopsis | http://www.atted.bio.titech.ac.jp/ | |
| 610 | Brassica BASC | Database for Brassica genomic research | http://hornbill.cspp.latrobe.edu.au/cgi-binpub/brassica/index.pl | |
| 1054 | CATdb | Arabidopsis transcriptome data | http://urgv.evry.inra.fr/CATdb | |
| 656 | DATF | Database of Arabidopsis transcription factors | http://datf.cbi.pku.edu.cn | |
| 935 | GABI-Kat | Flanking sequence tags for T-DNA insertions in Arabidopsis | http://www.GABI-Kat.de | |
| 1081 | GreenPhylDB | Comparative genomics of rice and Arabidopsis thaliana | http://greenphyl.cirad.fr | |
| 527 | MAtDB | MIPS Arabidopsis thaliana database | http://mips.gsf.de/proj/thal/db | |
| 1004 | PlantQTL-GE | Quantitative trait locus analysis in Arabidopsis and rice | http://www.scbit.org/qtl2gene | |
| 738 | RARGE | RIKEN Arabidopsis genome encyclopedia: cDNAs, mutants and microarray data | http://rarge.gsc.riken.jp/ | |
| 97 | TAIR | The Arabidopsis information resource | http://www.arabidopsis.org/ | |
| 627 | WAtDB | Wageningen Arabidopsis thaliana Database | No longer maintained | |
| 13.3. Rice | ||||
| 418 | BGI-RISe | Beijing Genomics Institute Rice Information System | http://rise.genomics.org.cn/ | |
| 1156 | DRTF | Database of Rice Transcription Factors | http://drtf.cbi.pku.edu.cn/ | |
| 79 | INE | Integrated rice genome explorer | http://rgp.dna.affrc.go.jp/giot/INE.html | |
| 353 | IRIS - | International Rice Information System | http://www.iris.irri.org | |
| 536 | MOsDB | MIPS Oryza sativa database | http://mips.gsf.de/proj/plant/jsf/rice/index.jsp | |
| 848 | OryGenesDB | Rice genes, T-DNA and Ds flanking sequence tags | http://orygenesdb.cirad.fr/ | |
| 628 | Oryza Tag Line | T-DNA insertion mutants of rice | http://urgi.versailles.inra.fr/OryzaTagLine/ | |
| 90 | Oryzabase | Rice genetics and genomics | http://www.shigen.nig.ac.jp/rice/oryzabase/ | |
| 860 | RAP-DB | Rice annotation project database | http://rapdb.dna.affrc.go.jp/ | |
| 737 | Rice Annotation DB | Contig data for manual annotation of rice genome | http://golgi.gs.dna.affrc.go.jp/SY-1102/rad/index.html | |
| 861 | Rice Mutant Database | Rice mutant database | http://rmd.ncpgr.cn/ | |
| 569 | Rice Pipeline | Unification tool for rice databases | http://cdna01.dna.affrc.go.jp/PIPE | |
| 572 | Rice Proteome DB | Rice proteome database | http://gene64.dna.affrc.go.jp/RPD/main_en.html | |
| 336 | RiceGAAS | Rice genome automated annotation system | http://ricegaas.dna.affrc.go.jp/ | |
| 13.4. Other plants | ||||
| 971 | ForestTreeDB | Annotated ESTs from diverse organs of conifer and poplar trees | http://foresttree.org/ftdb | |
| 1078 | Genome Database for Rosaceae | Genetics and genomics data on apple, cherry, peach, pear, raspberry, rose and strawberry | http://www.bioinfo.wsu.edu/gdr/ | |
| 80 | Legume Information System | Legume information server (formerly Medicago genome initiative): ESTs, gene expression and proteomic data | http://www.comparative-legumes.org/ | |
| 526 | MaizeGDB | Maize genetics and genomics database | http://www.maizegdb.org | |
| 1159 | MedicCyc | Biochemical pathways in Medicago truncatula | http://www.noble.org/mediccyc/ | |
| 539 | MtDB | Medicago trunculata Database | http://www.medicago.org/MtDB | |
| 921 | NRESTdb | Natural Rubber EST Database | http://genome.ukm.my/nrestdb/ | |
| 849 | Panzea | Maize genome project data | http://www.panzea.org | |
| 620 | PoMaMo | Potato Maps and More | https://gabi.rzpd.de/PoMaMo.html | |
| 766 | SGMD | Soybean genomics and microarray database | http://psi081.ba.ars.usda.gov/SGMD/default.htm | |
| 1132 | Shanghai Rapeseed Database | Seed development and fatty acid metabolism of oilseed crops | http://rapeseed.plantsignal.cn | |
| 919 | SoyBase | Genetic, genomic and phenotypic information about soybean | http://soybase.org | |
| 870 | SoyGD | Soybean genome database | http://soybeangenome.siu.edu | |
| 872 | TED | Tomato expression database | http://ted.bti.cornell.edu | |
| 874 | TIGR Maize database | Maize genome sequencing consortium site | http://maize.tigr.org | |
| 1016 | TomatEST DB | EST collection from multiple tomato species | http://biosrv.cab.unina.it | |
| 14. Immunological Databases | ||||
| 799 | AntiJen | Quantitative binding data for peptides and proteins of immunological interest | http://www.jenner.ac.uk/AntiJen | |
| 642 | BCIpep | Database of B-cell epitopes | http://bioinformatics.uams.edu/mirror/bcipep/ | |
| 604 | dbMHC | Genetic and clinical database of the human MHC | http://www.ncbi.nlm.nih.gov/mhc/ | |
| 813 | Epitome | Antigenic epitopes in proteins and antibodies that bind them | http://predictprotein.org/AifoEpi/ | |
| 150 | FIMM | Functional molecular immunology data | http://research.i2r.a-star.edu.sg/fimm | |
| 682 | Haptendb | Curated database of hapten molecules | http://www.imtech.res.in/raghava/haptendb/ | |
| 172 | IMGT | International immunogenetics information system: Immunoglobulins, T cell receptors, MHC, and RPI | http://imgt.cines.fr | |
| 503 | IMGT/GENE-DB | Vertebrate immunoglobulin and T cell receptor genes | http://imgt.cines.fr/cgi-bin/GENElect.jv | |
| 173 | IMGT/HLA | Polymorphism of human MHC and related genes | http://www.ebi.ac.uk/imgt/hla/ | |
| 504 | IMGT/LIGM-DB | Immunoglobulin, T cell receptor and MHC nucleotide sequences from human and other vertebrates | http://imgt.cines.fr/cgi-bin/IMGTlect.jv | |
| 779 | Immune epitope DB | Antibody and T cell epitopes for primates, rodents, and other animals | http://www.immuneepitope.org/ | |
| 367 | IPD | Immuno Polymorphism Database | http://www.ebi.ac.uk/ipd/ | |
| 692 | IPD-ESTDAB | Immunologically characterised melanoma cell lines | http://www.ebi.ac.uk/ipd/ | |
| 693 | IPD-HPA | Human platelet antigens | http://www.ebi.ac.uk/ipd/ | |
| 694 | IPD-KIR | Killer-cell Immunoglobulin-like Receptors | http://www.ebi.ac.uk/ipd/ | |
| 691 | IPD-MHC | Sequences of the major histocompatibility complex | http://www.ebi.ac.uk/ipd/mhc | |
| 361 | JenPep | Quantitative binding data for peptides and proteins of immunological interest | Superseded by AntiJen, no. 799 | |
| 702 | MHCBN | Database of MHC binding and non-binding peptides | http://www.imtech.res.in/raghava/mhcbn/ | |
| 181 | MHCPEP | MHC-binding peptides | http://bio.dfci.harvard.edu/DFRMLI/ | |
| 1101 | MUGEN Mouse DB | Murine models of immune processes and immunological diseases | http://www.mugen-noe.org/database/ | |
| 967 | SuperHapten | A comprehensive database for small immunogenic compounds | http://bioinformatics.charite.de/superhapten | |
| 621 | VBASE2 | Variable genes from the Ig loci of human and mouse | http://www.vbase2.org/ | |
a- Each database is shown in the list only once. In another version of this list, available at the NAR web site http://www.oxfordjournals.org/nar/database/a/, a database can be listed under two (sub)categories.
b- Accession number of the database in the on-line list; can be used to view the database summary. For example, http://www.oxfordjournals.org/nar/database/summary/1 shows the summary for DDBJ.
c- In some database names, the word "database" is abbreviated as "DB".
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